Cross-Sectional and Longitudinal Associations of Systolic Blood Pressure With Quality of Life and Depressive Mood in Older Adults With Cardiovascular Risk Factors: Results From the Observational DIAST-CHF Study

Herrmann‐Lingen, Christoph; Meyer, Thomas; Bosbach, Alexandra; Chavanon, Mira‐Lynn; Hassoun, Lina; Edelmann, Frank; Wachter, Rolf

doi:10.1097/psy.0000000000000591

Cited by 18 publications

(18 citation statements)

References 30 publications

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“…23 The relationship between higher systolic blood pressure and higher depressive symptoms was also seen in previous studies. 27,28 Some pathways are linked to the relationship between depression and cardiometabolic dysregulation. Prior studies have shown that unhealthy lifestyle and the presence of inflammatory cytokines could be involved in this relationship.…”

Section: Depression and Cardiovascular Risk In Older Adultsmentioning

confidence: 99%

Sintomas Depressivos estão Associados a Níveis Séricos Elevados de Colesterol de Lipoproteína de Baixa Densidade em Idosos com Diabetes Mellitus Tipo 2

Fittipaldi

Andrade

Santos

et al. 2020

Arquivos Brasileiros De Cardiologia

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Background: Type 2 Diabetes Mellitus (T2DM) is common in older adults, who also present a high level of risk factors for cardiovascular disease (CVD), such as dyslipidemia. However, the role of depression in T2DM patients and its relationship with CVD risk factors are understudied. Objective: The present study aimed to investigate the relationship between depressive symptoms (DS) and known cardiovascular risk factors in community dwelling older adults with T2DM. Methods: This is a cross sectional study, in which 85 community-dwelling older adults with T2DM were assessed. DS was assessed using the Yesavage Geriatric Depression Scale-short version (GDS-15). The following cardiovascular risk factors were evaluated: systolic (SBP) and diastolic blood pressure (DBP), fasting plasma glucose (FPG), lipid profile (serum triglycerides-TG, serum total cholesterol-TC, serum low-density lipoprotein cholesterol-LDL-C, and serum high-density lipoprotein cholesterol-HDL-C) and body mass index (BMI). Poisson multiple regression was performed to test the association between DS and each cardiovascular risk factor adjusted by sex, age, time spent in moderate physical activity, and functional status. The significance level adopted for the analysis was 5%. Results: Among all the analyzed risk factors, only high levels of LDL-C were related to high DS (PR=1.005, CI 95% 1.002-1.008). A significant association was observed between HDL-C levels (PR=0.99, CI 95% 0.98-0.99) and SBP (PR=1.009, CI 95% 1.004-1.014). Conclusion: In older adults with T2DM, the presence of DS was associated with LDL-C, HDL-C levels and SBP, even after adjusting for sex, age, physical activity level and functional capacity.

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Section: Depression and Cardiovascular Risk In Older Adultsmentioning

confidence: 99%

Sintomas Depressivos estão Associados a Níveis Séricos Elevados de Colesterol de Lipoproteína de Baixa Densidade em Idosos com Diabetes Mellitus Tipo 2

Fittipaldi

Andrade

Santos

et al. 2020

Arquivos Brasileiros De Cardiologia

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“…This can probably evidence about personal predisposition to AN, in patients with AH. In multivariate regression analyses, higher age, male gender, higher sodium intake, lower physical fitness, and alexithymia were independently and highly significantly associated with increased blood pressure, explaining altogether 39.5 % of the cross-sectional variation in mean arterial pressure [1].…”

Section: Discussionmentioning

confidence: 94%

“…Multicenter investigations concluded that depressive persistence influences cardiovascular diseases (CVD) progression as well as obesity and hypercholesterolemia [1]. The frequency of anxiety (AN) and depressive (DEP) disorders in patients with cardiovascular system pathology is ranged between 13-28%.…”

Section: Introductionmentioning

confidence: 99%

Anxiety and Depressive Disorders in Patients With Arterial Hypertension

et al. 2021

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The aim: To study the influence of anxiety and depressive disorders on life quality of patients with arterial hypertension. Materials and methods: 55 patients with arterial hypertension (AH) of 2nd stage were examined to reach the goal. Age diapason was 25-73 years, the middle age was 53.56+10.28. There were 58.2% (32) of women and 41.8% (23) of men among the patients. Results: Results analysis of the investigation of patients with arterial hypertension and anxiety and depressive disorders using the Spielberger-Khanin anxiety inventory showed moderate (30.9%) and high (69.1%) level of trait anxiety. As for the state anxiety the high level of it was confirmed in 74.6% of studied patients and moderate level of state anxiety in 25.5% of patients. During the analysis of gender-based distribution the trait anxiety level was significantly higher in women (p<0.05). Results of PHQ-9 showed subclinical depression level (12.7%), mild (49.1%) and moderate (16.4%). Moderate manifestations of depression were found in 12.7%, severe depression in 9.1% (5 individuals). As for the gender-based distribution, anxiety indicators were significantly higher in women (p<0.01). HADS method did not show significant difference of depression levels of gender-based distribution. Conclusions: The majority of individuals with arterial hypertension and nonpsychotic mental disorders have a high level of trait and state anxiety. Direct correlation was found between the trait anxiety indicator and depression severity, which were defined according to HADS and PHQ-9 questionnaires. The level of anxiety and depressive episode severity were found to be reliably higher in women in gender-based distribution, that/which was accompanied by decrease in most of the life quality indicators.

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“…In China, 6.9% of adults have reported depression [7], and nearly 40% of the population aged more than 60 has suffered from depressive symptoms [8]. Depression may increase stroke risk through several potential pathways, including dysregulation of the immune system and induction of inflammation [9], unhealthy behaviors [10], decreased medication adherence [11] and the development of hypertension and diabetes [12,13].…”

Section: Introductionmentioning

confidence: 99%

Prospective association between depressive symptoms and stroke risk among middle-aged and older Chinese

et al. 2021

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Background This study aimed to assess the association between baseline symptoms and changes in depressive symptoms and stroke incidents. Methods We used data from the Chinese Health and Retirement Longitudinal Study conducted in 2013, 2015, and 2018. In total, 10,100 individuals aged ≥45 years and without a history of stroke in 2013 were included. Depressive symptoms were measured using the 10-item version of the Center for Epidemiological Studied Depression scale (elevated depressive symptoms cutoff ≥10). Changes of depressive symptoms were assessed by two successive surveys (stable low/no, recent onset, recently remitted, and stable high depressive symptoms). We assessed whether baseline depressive symptoms and changes of them were associated with stroke incidents reported through 2018. Logistic regression analyses adjusted for age, gender, education, marital status and other potential confounders were performed. Results For the analysis of baseline depressive symptoms and stroke (n = 10,100), 545 (5.4%) reported stroke incidents in the following 5-year period. Individuals with elevated depressive symptoms in 2013 experienced a markedly higher stroke risk (odds ratio (OR) = 1.53, 95% confidence interval (CI) = 1.28–1.84) compared with those without elevated depressive symptoms. In the analysis of changes in depressive symptoms (n = 8491, 430 (5.1%) stroke events), participants with stable high (OR = 2.01, 95% CI = 1.58–2.56) and recent-onset (OR = 1.39, 95% CI = 1.04–1.85) depressive symptoms presented higher stroke risk compared to those with stable low/no depressive symptoms, while recently remitted symptoms (OR = 1.12, 95% CI = 0.80–1.57) were not associated with stroke risk. Conclusions In conclusion, stable high and newly started depressive symptoms were associated with increased stroke risk, whereas the improvement of depressive symptoms was not related to increase in stroke risk, suggesting that stroke risk may be decreased by effective management of depressive symptoms.

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Cross-Sectional and Longitudinal Associations of Systolic Blood Pressure With Quality of Life and Depressive Mood in Older Adults With Cardiovascular Risk Factors: Results From the Observational DIAST-CHF Study

Abstract: In older adults with cardiovascular risk factors, higher systolic blood pressure readings are independently related to better quality of life and fewer depressive symptoms in both cross-sectional and longitudinal settings, although the magnitude of the effect sizes is typically small.

Cited by 18 publications

References 30 publications

Sintomas Depressivos estão Associados a Níveis Séricos Elevados de Colesterol de Lipoproteína de Baixa Densidade em Idosos com Diabetes Mellitus Tipo 2

Sintomas Depressivos estão Associados a Níveis Séricos Elevados de Colesterol de Lipoproteína de Baixa Densidade em Idosos com Diabetes Mellitus Tipo 2

Anxiety and Depressive Disorders in Patients With Arterial Hypertension

Prospective association between depressive symptoms and stroke risk among middle-aged and older Chinese

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