Cross‐sensitivity between resorcinol, resorcinol monobenzoate and phenyl salicylate

Nakagawa, Mikio; Kawai, Kehchi; Kawai, K.

doi:10.1111/j.1600-0536.1992.tb05263.x

“…Positive patch test reactions to MP (and to FM I) are very frequently observed in patients who are photoallergic to ketoprofen; the mechanism behind this has not been elucidated. 134,135 Patients sensitized to resorcinol monobenzoate almost 136 invariably react to MP 11,115,116 ;…”

Section: Other Co-reactionsmentioning

confidence: 99%

“…Positive patch test reactions to MP (and to FM I) are very frequently observed in patients who are photoallergic to ketoprofen; the mechanism behind this has not been elucidated . Patients sensitized to resorcinol monobenzoate almost invariably react to MP; conversely, only 0% to 16% of patients sensitized to MP co‐react to resorcinol monobenzoate . Resorcinol monobenzoate has not been identified in MP, and the mechanism behind the co‐reactivity is unknown.…”

Section: Cross‐reactions Pseudo‐cross‐reactions and Co‐reactionsmentioning

confidence: 99%

Myroxylon pereiraeresin (balsam of Peru) – A critical review of the literature and assessment of the significance of positive patch test reactions and the usefulness of restrictive diets

Groot¹

2019

View full text Add to dashboard Cite

In this article, contact allergy to Myroxylon pereirae resin (MP) (balsam of Peru) is reviewed. The topics presented include the uses, the chemical composition, the frequency of sensitization, the relevance of positive reactions, the MP-containing products causing allergic contact dermatitis, co-reactivity with other fragrance and nonfragrance materials, the sensitizers, the usefulness of MP as a "marker" of fragrance allergy, and the effectiveness of, and indications for, "balsam-restrictive" diets. Sensitization to MP occurs in 4% to 8% of patients routinely tested for suspected contact dermatitis. There are few adequate data on relevance. Topical pharmaceuticals were formerly, but are not today, important sources of sensitization. Cosmetics and foods or drinks are hardly ever products responsible for sensitization to MP. Positive patch test reactions in the large majority probably result from previous sensitization to MP constituents because of their presence in fragrances and fragranced products, MP thereby acting as marker (or "indicator") of fragrance allergy. However, fragrance mix I is a more sensitive marker, and the added diagnostic value of testing with MP is unknown. The allergenic ingredients of MP include isoeugenol, eugenol and cinnamyl alcohol, but there are other-largely unknown-chemicals that are responsible for contact allergy. Suggestions are given for further research to address questions thus far unanswered and to improve patient care. K E Y W O R D Sbalsam of Peru, balsam-restrictive diet, chemical composition, eugenol, cinnamyl alcohol, coniferyl benzoate, fragrance, isoeugenol, Myroxylon pereirae resin, perfume, fragrance marker, contact allergy

show abstract

“…Spectacle frames are the most common sources of resorcinol monobenzoate contact allergy cases reported in the literature [1, 4, 5, 6, 7] whereas hearing aids [1], pens [1, 5] or steering wheels [5, 8] are only occasionally mentioned.…”

Section: Discussionmentioning

confidence: 99%

“…A Japanese group reported a cross-sensitivity reaction between resorcinol monobenzoate and phenyl salicylate in a patient with eyeglass frame dermatitis. The spectacles contained both stabilizers and the author could not determine which one was the primary allergen [6]. Three similar cases were described by Sonnex and Rycroft [7], but the eyeglass frames of these patients did not contain resorcinol monobenzoate.…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Contact Allergy to Resorcinol Monobenzoate

Ongenae

¹

,

Matthieu²,

Constandt³

et al. 1998

View full text Add to dashboard Cite

Resorcinol monobenzoate is an ultraviolet light absorber used in cellulose plastics and is known to cause allergic contact dermatitis reactions. It is the most important allergen in spectacle frames but can be a potential allergen in shoes as well. We report 7 cases of allergy to resorcinol monobenzoate with different clinical presentations. Our series further illustrates several possible cross-sensitizers.

show abstract

Resorcin [MAK Value Documentation in German language, 2002]

2012

The MAK‐Collection for Occupational Health and Safety

0

View full text Add to dashboard Cite

Veröffentlicht in der Reihe Gesundheitsschädliche Arbeitsstoffe , 35. Lieferung, Ausgabe 2002 Der Artikel enthält folgende Kapitel: Allgemeiner Wirkungscharakter Wirkungsmechanismus Toxikokinetik und Metabolismus Erfahrungen beim Menschen Einmalige Exposition Wiederholte Exposition Wirkung auf Haut und Schleimhäute Allergene Wirkung Reproduktionstoxizität Genotoxizität Kanzerogenität Tierexperimentelle Befunde und In‐vitro‐Untersuchungen Akute Toxizität Subakute, subchronische und chronische Toxizität Wirkung auf Haut und Schleimhäute Allergene Wirkung Reproduktionstoxizität Genotoxizität Kanzerogenität Sonstige Wirkungen Bewertung

show abstract

Cross‐sensitivity between resorcinol, resorcinol monobenzoate and phenyl salicylate

Cited by 15 publications

References 1 publication

Myroxylon pereiraeresin (balsam of Peru) – A critical review of the literature and assessment of the significance of positive patch test reactions and the usefulness of restrictive diets

Myroxylon pereiraeresin (balsam of Peru) – A critical review of the literature and assessment of the significance of positive patch test reactions and the usefulness of restrictive diets

Contact Allergy to Resorcinol Monobenzoate

Resorcin [MAK Value Documentation in German language, 2002]

Contact Info

Product

Resources

About