In this article, deep neural network (DNN) and chain parameter methods are used to analyze the crosstalk coupling of a star‐quad and a twisted bundle of twisted wire pairs (TBTWP) cables for different excitations, respectively. A DNN is used to extract the per‐unit‐length (p.u.l) resistance, inductance, capacitance, and conductance (RLCG) parameters at any position for the star‐quad and TBTWP cables. The induced common mode (CM) and differential mode (DM) currents due to crosstalk are calculated by combining the obtained RLCG parameters with the chain parameter method. The obtained results show good agreement with that of FEKO software. Moreover, it is found that the star‐quad cable can reduce the external coupling more effectively than that of the TBTWP cable. Finally, measurements are performed to further validate the accuracy of our proposed algorithm.