Cryosurgery in E.N.T. practice

Holden, H. B.

doi:10.1017/s0022215100075927

Cited by 18 publications

(8 citation statements)

References 11 publications

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“…There is evidence that cell death by freezing is accompanied by antigen formation, probably through the liberation of lipoprotein complexes from cell membranes (Shulman, Yantorno & Bronson, 1967). Apart from rises in circulating antibody titres following the cryodestruction of tumours, increased lymphocyte activity has been demonstrated (Holden, 1972).…”

Section: A D V a N T A G E S A N D L I M I T A T I O N S O F C R Y O mentioning

confidence: 99%

Practical cryosurgery—an introduction for small‐animal Clinicians*

Lane

1974

J of Small Animal Practice

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Cryosurgical equipment has been produced which is suitable for use in general veterinary practice and which need not be excessively expensive. A knowledge of the underlying principles of cryosurgery is essential if the advantages of this technique are to be gained in full. There is reason to expect an expansion in the list of conditions for which cryosurgical treatment will be preferred to conventional methods.

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Section: A D V a N T A G E S A N D L I M I T A T I O N S O F C R Y O mentioning

confidence: 99%

Practical cryosurgery—an introduction for small‐animal Clinicians*

Lane

1974

J of Small Animal Practice

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“…9Y11,13,14 In the field of otolaryngology, it is used for resection of various benign lesions (laryngeal papilloma, hemangioma, vocal polyp, nodule, and dysplasia), prevention of bleeding during tonsillectomies, symptomatic relief of rhinitis, control of nasal bleeding, hypophysectomy, Ménière disease, and malignant tumors for curative, palliative, and adjunctive treatment. 9,10 Short-term mucosal contact at a temperature of j70-C leads to a denaturation of cellular proteins and intracellular electrolyte displacement. As endothelial cells react in a similar way, microthrombosis forms in the vessels and causes a perfusion disturbance with resultant consecutive tissue ischemia.…”

Section: Discussionmentioning

confidence: 99%

Endoscopic Cryotherapy for the Treatment of Epistaxis Due to Hereditary Hemorrhagic Telangiectasia

Kim¹,

Oh²,

Kim³

et al. 2014

Journal of Craniofacial Surgery

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Hereditary hemorrhagic telangiectasia (HHT), an autosomal dominant vascular disease, involves mainly skin, mucocutaneous membranes, and viscera. Epistaxis is one of the most common symptoms of HHT, and chronic, frequently relapsing epistaxis can cause symptoms such as iron deficiency anemia, severe crusting, and nasal obstruction that can cause lower quality of life. Treatments for HHT range from medication and conservative management to more aggressive surgeries. None of the treatment options, however, have had satisfactory outcomes until now. We introduced cryotherapy for a patient with HHT and at least a 10-year history of frequent, severe epistaxis. This treatment strategy resulted in successful management of symptoms and no associated complications. We present herein a literature review and the clinical course and symptoms of an HHT patient who underwent cryotherapy.

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“…Clinically, endoscopic cryo-surgery has been successfully used to treat infantile laryngeal papillomas [Muler, 1969;Baron et al, 1970;Holden, 1972], apparently without permanent damage to laryngeal function. Our technique for treating post-intubation stenosis is simple: using a modified laryngoscopic microsurgery technique, the stenosis is opened and a cylin drical cryo-probe introduced, cooling the probe for 2-3 min.…”

Section: Clinical Experiencesmentioning

confidence: 99%

Management of Laryngo-Tracheal Stenosis in Children

Kellerhals¹

1974

ORL

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Post-intubation stenosis in children is often not amenable to surgical treatment; nor can it easily improve by endoscopic insertion of endoprostheses, as in some adult cases. Endoscopic cryosurgery appeared to provide a new means for such cases. Experimental studies have shown that cryo-necrosis of cartilage does not necessarily interfere with the growth of the laryngo-tracheal cartilaginous structures, and new formation of cartilage prevents the loss of mechanical stability. Preliminary clinical results are reported on patients who did not seem suited for any other therapeutic procedure and were successfully treated by means of endoscopic cryo-surgery.

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Cryosurgery in E.N.T. practice

Cited by 18 publications

References 11 publications

Practical cryosurgery—an introduction for small‐animal Clinicians*

Practical cryosurgery—an introduction for small‐animal Clinicians*

Endoscopic Cryotherapy for the Treatment of Epistaxis Due to Hereditary Hemorrhagic Telangiectasia

Management of Laryngo-Tracheal Stenosis in Children

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