Cryosurgery of Liver Tumors

Мерзликин, Н. В.; Цхай, В. Ф.; Brazhnikova, N. A.; Комкова, Т. Б.; Сало, В. Н.; Maksimov, M. A.; Навасардян, В. Г.; Нороева, Т. А.

doi:10.21294/1814-4861-2018-17-2-41-48

Cited by 4 publications

(1 citation statement)

References 0 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…В Томском гепатологическом центре при операциях на печени, в том числе при злокачественных опухолях, применяется криовоздействие для обработки культи печени. Приводим клинический случай успешной резекции печени при гепатоцеллюлярном раке больших размеров [3,4] Общий анализ крови: Hb -134 г/л, эритроциты -4,7×10 12 /л, лейкоциты -9,9×10 9 /л, СОЭ -52 мм/час. Анализ мочи без отклонений от years.…”

Section: актуальностьunclassified

Cryosurgery in the Treatment of Liver Cancer: A Case Report

et al. 2019

Self Cite

View full text Add to dashboard Cite

Background. Hepatocellular carcinoma is the most common liver cancer and is a leading cause of cancerrelated death worldwide. Its aggressiveness and extensive dissemination lead to a poor patient prognosis. The 5-year survival rate does not exceed 15 %. Despite advances in imaging techniques, its curable rate remains low, because signs and symptoms of liver cancer do not usually appear until the late stages. There is no standard curative treatment for advanced liver cancer.Description. We present the case of a 56- year-old female patient with stage T3N0M0 hepatocellular carcinoma. The patient had a tumor of 20 cm in diameter and 2400 g in weight. The patient underwent right hemihepatectomy and cryodestruction of the liver stump along the resection margin. No evidence of tumor recurrence was found with a follow-up of 12 years.Conclusion. Cryodestruction of the liver stump along the resection margin increases the potential for a higher cure rate in patients with hepatocellular carcinoma, even in cases of extensive organ damage in the absence of metastasis and tumor ingrowth into surrounding organs.

show abstract

Section: актуальностьunclassified

Cryosurgery in the Treatment of Liver Cancer: A Case Report

et al. 2019

Self Cite

View full text Add to dashboard Cite

show abstract

Analysis of surgical treatment of liver hemangiomas

Мугатаров

Zarivchatsky

Самарцев

et al. 2021

Perm Medical Journal

View full text Add to dashboard Cite

Objective. Development of criteria for optimal tactics of surgical treatment of liver hemangiomas of various sizes and localizations. Materials and methods. A retrospective analysis of 247 patients with hepatic hemangiomas observed on an outpatient basis and in a hospital was carried out; 59 of them (23.89 %) were operated including 12 men and 47 women over the period of 19992019. Liver resection with hemangioma was performed in 30 patients, hemangioma enucleation in 21, X-ray endovascular occlusion in 8 patients. The diagnosis was established on the basis of ultrasound of the abdominal organs, CT and MRI with contrast as well as angiographic research methods. Results. The postoperative complications developed in 4 (6.78 %) cases: reactive pleurisy was detected in 2 patients after the right-sided hemihepatectomy, hematomas in the resection zone of segments of the right lobe of the liver with a tumor were diagnosed in 2 patients. All complications were eliminated by conservative measures. There were no lethal outcomes. Conclusions. Surgical treatment of patients with hemangiomas includes resection of the liver with a tumor, enucleation of the hemangioma, and various types of local destruction. In order to reduce the blood circulation of the tumor and decrease the risk of intraoperative blood loss, the ECA of the branches of the hepatic artery was indicated. A comparative analysis of the results of treatment of patients with liver hemangiomas using various methods of surgical interventions made it possible to develop optimal surgical tactics, a system of intra- and perioperative safety in this category of patients.

show abstract

Cryosurgery and physical medicine n treatment of cancer

2021

View full text Add to dashboard Cite

Background. At the present stage of oncology development, cryosurgery is keeping up with other surgical options of treating malignant tumors. However, especially when using cryoapplication technique, radical low-temperature destruction of large tumors is challenged with uneven freezing of the tissue inside and on the periphery of the cryoablation zone resulting in insufficient complete destruction of all tumor cells. The long-term strategy of increasing the efficiency of cryogenic treatment, which will maximize the potential for exposure of biological tissues to low temperatures, is its combination with other physical methods. On the other hand, the preliminary cryotherapy of the tumor tissue can be used to increase the efficiency of antitumor therapy by other methods, in particular, physical ones. Purpose – to summarize and analyze the literature data on applying low temperatures in combination with other physical medicine techniques in order to assess the efficiency and the potential of those in uptodate oncology. Materials and Methods. The paper deals with analyzing the studies published within the period from 2000 to 2020 outlining the data on the impact of low temperatures on the biological tissues in combination with other physical medicine techniques. After keyword search against international and Ukrainian databases, the papers, focused on this subject area, were sorted out, analyzed and included in the references. Results. The review presents pros and cons of using cryosurgery in medical practice with due regard for pathogenetic mechanisms of low temperature impact on biological structures. Based on experimental and clinical studies data, a positive effect of cryosurgical approaches in combination with other physical medicine techniques when performing surgical interventions for ablation of malignant neoplasms has been shown. The paper included the contributions describing the findings on combining cryosurgery with: preliminary hemodilution; radiofrequency and microwave hyperthermic ablation; laser and photodynamic therapy; electroporation. Additionally, a contemporary view of cryo-ultrasound therapy, cryonanoablation, cryo- radiation treatment and cryoelectrolysis was presented. Conclusions. Cryosurgery is an effective minimally invasive surgical method keeping up with other methods of treating malignant tumors, despite the fact that these days the research on optimizing the method of exposure of biological tissues to low temperatures is still ongoing. Cryosurgery in combination with other physical medicine techniques in case of tumor ablation can enhance the effectiveness of treating cancer patients.

show abstract

Cryosurgery of Liver Tumors

Cited by 4 publications

References 0 publications

Cryosurgery in the Treatment of Liver Cancer: A Case Report

Cryosurgery in the Treatment of Liver Cancer: A Case Report

Analysis of surgical treatment of liver hemangiomas

Cryosurgery and physical medicine n treatment of cancer

Contact Info

Product

Resources

About