“…Examples of such compounds bearing 1,2,4-triazole residues are fluconazole, the powerful azole antifungal agent, as well as the potent antiviral N-nucleoside ribavirin. 1,2 The 1,2,4-triazole nucleus is associated with diverse pharmacological activities such as antibacterial, hypoglycemic, antihypertensive, analgesic, and specific magnetic properties. 3,4 In recent years, there has been an increasing interest in the chemistry of thiophenes because of their biological significance.…”