Crystal structure of ethyl 2-(2,4,5-trimethoxyphenyl)quinoline-4-carboxylate

Abstract

In the title compound, C21H21NO5, the dihedral angle between the quinoline ring system (r.m.s. deviation = 0.028 Å) and the tri­meth­oxy­benzene ring is 43.38 (5)°. The C atoms of the meth­oxy groups deviate from their attached benzene ring by −0.396 (2), −0.049 (2) and 0.192 (2) Å for the ortho-, meta- and para-substituents, respectively. The pendant ethyl chain is disordered over two orientations in a 0.527 (5):0.473 (5) ratio. A short intra­molecular C—H⋯O contact closes an S(6) ring. In the crystal, inversion dimers linked by pairs of weak C—H⋯O inter­actions generate R 2 2(6) loops. The dimers are linked by further C—H⋯O inter­actions to generate [1-10] chains.