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In the title compound, C21H21NO5, the dihedral angle between the quinoline ring system (r.m.s. deviation = 0.028 Å) and the tri­meth­oxy­benzene ring is 43.38 (5)°. The C atoms of the meth­oxy groups deviate from their attached benzene ring by −0.396 (2), −0.049 (2) and 0.192 (2) Å for the ortho-, meta- and para-substituents, respectively. The pendant ethyl chain is disordered over two orientations in a 0.527 (5):0.473 (5) ratio. A short intra­molecular C—H⋯O contact closes an S(6) ring. In the crystal, inversion dimers linked by pairs of weak C—H⋯O inter­actions generate R 2 2(6) loops. The dimers are linked by further C—H⋯O inter­actions to generate [1-10] chains.

Choline Chloride/Urea Ionic Liquid Catalyzed a Convenient One-Pot Synthesis of Indole-3-propanamide Derivatives. -A versatile and general method for the synthesis of indole-3-propanamides (V) is development using the three-component reaction of indole (I) with Meldrum's acid and aldehydes and subsequent reaction of the Meldrum's adduct formed with amines. Treatment of the Meldrum's adducts with water affords exclusively the corresponding propanoic acids (VII). -(SIDDALINGAMURTHY, E.; MAHADEVAN*, K. M.; KUMAR, T. O. S.; Synth. Commun. 43 (2013) 23, 3153-3162, http://dx.

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