Crystal Structure of Maturin acetate from <i>Psacalium peltatum</i> (Kunth) (<i>matarique</i>)

Abstract

Psacalium peltatum (Kunth) Cass. is an endemic medicinal plant member of the matarique complex, widely distributed in the central part of Mexico. The roots of P. peltatum have been employed as alcoholic maceration to treat conditions that induce inflammation from such as wounds, skin ulcers and rheumatism. 1 Our research has shown that furanoeremophilanetype sesquiterpene, maturin acetate (I) is the main constituent of this resin. Although maturin acetate has been isolated as the most abundant natural product in of Mexican species, such as P. beamanii, 2 Roldana angulifolia, 3 and Trichilia cuneata, 4 no report on the crystal structure determination of this compound has appeared. Therefore, due to this lack of data and x-ray studies, the crystal structure determination of maturin acetate was undertaken.Roots of Psacalium peltatum (Kunth) Cass., were collected from a pine-oak forest of Mineral del Chico, Hidalgo, Mexico, [20˚09¢55≤ N and 98˚45¢08≤ W]. A voucher specimen was deposited at the National Herbarium (MEXU 1138692) of the Institute of Biology, UNAM, Mexico. Air-dried and powdered roots (4.381 kg) of P. peltatum were sequentially extracted with hexane by exhaustive maceration (3 times ¥ 2 L), at room temperature. Hexane extract of roots from P. peltatum, was separated in a column chromatographic process and elueted with hexane-ethyl acetate in a mixture gradient, from fraction (98:2) elueted of hexane-ethyl acetate was isolated Maturin acetate and their spectroscopic features were compare with the described data. 5,6 A yellow crystal prism was mounted on a glass fibber. The X-ray intensity data were measured at 298 K on a Bruker Smart