Crystal structure of pyrogallol[4]arene complex with phosphocholine: A molecular recognition model for phosphocholine through cation–π interaction

Process Development for Separation of Conformers from Derivatives of Resorcin[4]arenes and Pyrogallol[4]arenes

“…The bowl‐shaped cavity of the RsC and PgC also works as perfect host for guest molecules of different shapes and functionalities . These structural features are useful not only in the construction of various supramolecular frameworks, such as hydrogen‐bonded dimers/hexamers and metal‐seamed dimers/hexamers, but also in the applications of RsC and PgC in the field of, for example, molecular recognition, host–guest complexes, gas sorption and separation …”

Selective recognition of choline phosphate by tripodal hexa-urea receptors with dual binding sites: crystal and solution evidence

“…Moreover, it is worth noting that the current complexes are rare examples of X-ray crystal evidence of a host–guest complex with CP. The only other known example is the complex of a pyrogallol[4]arene receptor, in which the cationic Me 3 N– + head of CP forms cation–π interactions while the phosphate is involved in hydrogen bonding with the hydroxyl groups of the receptor and lattice water molecules 10…”

“…Moreover, contrary to the commonly focused PC (di-ester) derivatives, studies targeted on CP are scarce. To our knowledge, only two examples of artificial receptors for CP have been reported 7,10. Thus, exploration of new strategies for selective binding and sensing of CP is still highly desirable.…”

Metal Organic Nanocapsules as Two-Dimensional Network Building Blocks

“…Recently, the Atwood group reported that coordination polymers can be formed using pyrogallol[4]­arene-based metal organic nanocapsules (MONCs) as secondary building units. Pyrogallol[4]­arenes (PgCs) are calixarene-like macrocyclic molecules that are used primarily as supramolecular building blocks in materials constructed through noncovalent means. − However, with an upper rim consisting of 12 phenolic hydroxyl groups, these macrocycles can also function as coordinative building blocks in the construction of more complex superstructures. Common structural motifs of PgC-based entities include the hexameric (PgC) 6 M 24 and dimeric (PgC) 2 M 8 MONCs formed with transition metal cations − and the infinite-layered networks formed with alkali cations, , among others. , The cage-like coordination complexes formed from transition metal cations are very similar in size and shape to their noncovalently seamed complementary supramolecules , and feature two distinct coordination patterns: eight distinct trimetal clusters in the hexamer and an “octametal belt” in the dimer. ,− , The coordination number of the metal cations is also different in the two motifs, with tetra- or hexacoordinate sites seen in the hexamer and pentacoordinate sites typically seen in the dimer.…”