Crystal Structures of Palladium(II) Ternary Complexes of 5-X-2-Aminobenzoic Acid with 1,10-Phenanthroline and Their Interaction with Calf Thymus DNA (Where X=Cl, Br and I)

Investigations on Nuclease Activity of Trans Mixed Ligand- Copper(ii) Complexes With Ortho Substituted Aromatic Oximes and Heterocyclic Bases

“…In this study, we have attempted to unravel the DNA interactions and nuclease activity of mixed ligand copper complexes. The reduction in peak intensity (absorption spectra) is in analogy with similar observation made earlier for other mixed ligand complexes 30,31 . Since the binding constants values are appreciable and less than 10 6 M -1 and since the complexes contain aromatic hydrophobic groups these complexes may be better regarded as partial intercalators of DNA.…”

Structures and Interaction with DNA of Ternary Palladium(II) Complexes: [Pd(Gly)(X)] (Gly=Glycine; X=2,2′-Bipyridine, 1,10-Phenanthroline and 2,2′-Bi-pyridylamine)

“…[2][3][4][5] Palladium(II) complexes have been also investigated for developing the new antitumor agents, [6][7][8][9][10][11][12] because palladium(II) has a similar coordination mode and chemical properties to platinum(II).12) As the result, several novel palladium(II) complexes having antitumor citotoxic activities against MCF-7, TK-10 and UACC-62 human tumor cell lines, 13) and P388 lymphocytic leukemia cells have been found. [14][15][16][17] In these complexes, the ternary palladium(II) complexes with a heterocyclic ligand and L-glycine one, [Pd(Gly)(X)] (where X is a heterocyclic ligand; 2,2Ј-bipyridylamine(bpa), 15) 1,10-phenanthroline (phen) 16) and 2,2Ј-bipyridine(bpy) 17) ) have the antitumor activity against P388 lymphocytic leukemia cells.…”

“…[2][3][4][5] Palladium(II) complexes have been also investigated for developing the new antitumor agents, [6][7][8][9][10][11][12] because palladium(II) has a similar coordination mode and chemical properties to platinum(II).…”

On the energetic stability of halogen bonds involving metals: implications in crystal engineering

“…For Pd( ii ), two structures were selected (see Fig. 2), which form homodimers in the solid state where the C–Br bond is pointing to the middle of the Ni–O coordination bond in RECTEZ 40 and the Ni–Br coordination bond in REYJAH . 41 Therefore, in both structures, bifurcated HaBs are formed.…”

“…1 shows two selected X-ray structures involving Ni(II) as the electron donor and bromine (refcode PUGRIU) 38 or iodine (refcode VAPVAK) 39 For Pd(II), two structures were selected (see Fig. 2), which form homodimers in the solid state where the C-Br bond is pointing to the middle of the Ni-O coordination bond in RECTEZ 40 and the Ni-Br coordination bond in REYJAH. 41 Therefore, in both structures, bifurcated HaBs are formed.…”