Crystallography of biological fluid as a method for evaluating its physicochemical characteristics

Abstract

Using an integral qualitative and quantitative approach to the studies of initiation of the biological material crystallogenesis, we showed in experiments with normal human saliva that the external characteristics of biological fluid (pH, osmolality, and environmental temperature) determine the results of crystallization (tesigraphic facies). The main external (macroenvironment) and inner (microenvironment) factors of biological fluid crystal formation, determining specific features of the tesigraphic facies, were distinguished and classified. The informative value of differential analysis of biomaterial properties by means of modulating the environmental conditions is established.

Droplet Drying Patterns on Solid Substrates: From Hydrophilic to Superhydrophobic Contact to Levitating Drops

“…Morphology of the salt crystals is very sensitive to the kind of salt, concentration, and type of colloidal particles, as well as the rate of evaporation [24-26, 29, 142, 144-148]. This sensitiveness allows using the morphology of salt crystals as an indicator, for example, to diagnose different diseases by drying drops of biological fluids [139,149].…”

“…In the 1980s-1990s, doctors of the former Soviet Union began to use the appearance of structures formed by drying droplets of biological fluids for the diagnosis of various diseases [3,4,81,181,267]. Unfortunately, very few of these articles were published in English [62,138,140,149,182,217].…”

Physical and Biochemical Characteristics of Biological Fluids in Rats with Modeled Thermal Injury

“…Crystallogenic characteristics of the serum and urine were studied by the classical crystalloscopic method, the initiator capacity of biological medium was studied using differential tesigraphy [1,4,5]. Saline (0.9% NaCl) served as the basal substance in the tesigraphic test.…”

“…Saline (0.9% NaCl) served as the basal substance in the tesigraphic test. Crystalloscopic and tesigraphic facies were described using a system of quantitative tests [4,5]. Micropreparations were examined in 3 non-overlapping visual fields.…”

Aggregation of Crystalline Copper Sulphate Salt in a Gelatin Medium

“…[1][2][3][4] Drying salt in colloidal gel develops aggregating systems and draws a keen attention for scientific and industrial purposes, 5,6 for e.g. to ensure the sustained growth of evenly dispersed pigments in a solution during drying, it is important to control the distribution of solute, 7 crystallographic deposition of metal salts in biological fluid is important to know its physiochemical properties, 8 study of blood drop evaporation 9,10 is helpful in diagnosis of several diseases. Growth morphology of aggregated patterns is quite complex, it depends on particle shape and size, nature of solvent, solute concentration and temperature, pressure, humidity of the ambient system.…”