CSF Otorrhea Resulting from Osteoradionecrosis of the Temporal Bone in a Patient with Recurrent Meningioma

Park, Chul Won; Jin, Bong Joon; Jeong, Sang Won; Min, Hyun Jeong; Shin, Ji Hoon; Lee, Seung Hwan

doi:10.3342/ceo.2009.2.2.97

Cited by 14 publications

(7 citation statements)

References 7 publications

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“…The mandible is one of the most frequently affected bones 2,6,11,[17][18][19] . ORN has been reported as the major complication of irradiation in head and neck cancer 2,[5][6][7]11,13,[20][21][22] . However, many etiologic factors of ORN have been reported in the Conservative treatment of osteoradionecrosis literature.…”

Section: Case Reportmentioning

confidence: 99%

Successful in a conservative treatment of osteoradionecrosis of the jaw: a case report and review of literature

Moraes

Thomaz

Silva

et al. 2016

RGO, Rev. Gaúch. Odontol.

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Osteoradionecrosis of jaws is one of the most serious complications of radiation therapy for head and neck malignancies. RESUMOOsteorradionecrose dos maxilares é uma das complicações mais sérias da radioterapia para o tratamento de tumores de cabeça e pescoço. O manejo da osteorradionecrose continua sendo discutido e há poucos relatos de casos descrevendo modalidades de tratamento conservadoras. Este artigo apresenta um caso de osteorradionecrose na mandíbula de um paciente de 58 anos de idade, após a realização de exodontia e explora uma modalidade de tratamento conservador com um follow-up de três anos. Foram combinadas antibioticoterapia e irrigação diária utlizando clorexidina. Após três anos é possível observar a resolução do caso em imagens de tomografia computadorizada de feixe cônico e reconstruções 3D. As imagens evidenciam remodelação óssea após este período de acompanhamento e sem a presença de osso exposto. Pode-se concluir que a terapia proposta resultou em sucesso e o paciente continua em acompanhamento periódico.

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Section: Case Reportmentioning

confidence: 99%

Successful in a conservative treatment of osteoradionecrosis of the jaw: a case report and review of literature

Moraes

Thomaz

Silva

et al. 2016

RGO, Rev. Gaúch. Odontol.

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“…It is important to recognize this entity because the diagnosis may preclude potentially harmful diagnostic intervention and allow more appropriate therapy [38]. The temporal bone has been affected by ORN after irradiation of nasopharyngeal carcinomas [39,40].…”

Section: Clinical Characteristicsmentioning

confidence: 99%

Osteoradionecrosis of the Jaws

Bagán

Scully

Zapater

et al. 2011

Clinic Rev Bone Miner Metab

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Osteoradionecrosis (ORN) is one of the most serious oral complications of head and neck cancer treatment with radiotherapy. There is bone tissue necrosis and failure to heal. The bone becomes devitalized and exposed through the overlying skin or mucosa, without healing for 3 months, without the recurrence of tumor. We review the etiological factors implicated in the ORN and describe the influence of infection, radiation therapy, dental status, and surgery. Finally, we present the currently accepted therapeutics procedures for the management of osteoradionecrosis.Keywords Osteoradionecrosis Á Jaws Á Bone necrosis Osteoradionecrosis (ORN) is one of the most serious oral complications of head and neck cancer treatment. It is characterized by a severe delayed radiation-induced injury, characterized by bone tissue necrosis and failure to heal [1-3], and several definitions have been proposed. One of the most widely accepted is that published by Harris [4]. He describes ORN as an irradiated bone that becomes devitalized and exposed through the overlying skin or mucosa, without healing for 3 months, without the recurrence of tumor. Marx [5] defined ORN as an area greater than 1 cm of exposed bone in a field of irradiation that had failed to show any evidence of healing for at least 6 months.Given the increased use of radiation therapy (RT) and combined chemotherapy-radiation therapy (CRT) regimens in the treatment of head and neck malignancies, it is anticipated that osteoradionecrosis will continue to be an important clinical problem [6], though newer radiotherapy techniques may reduce ORN to a degree, as discussed below.No studies to date have systematically addressed the impact of ORN on either quality of life or cost of care [7]. EpidemiologyIn a retrospective study of 830 patients with head and neck tumors who received radiotherapy between 1969 and 1999, there was an incidence of ORN of 8.2% and a threefold higher incidence in men than in women [8]. In contrast, Cheng et al. [9] in 2006 found the prevalence to be 2.7%.New cancer treatment strategies such as intensity-modulated RT (IMRT) and concomitant CRT have had disappointingly minimal effect on the prevalence of ORN. In a review of 43 articles published between 1990 and 2008, Peterson et al. [7] found that the weighted prevalence for ORN in conventional RT was 7.4%, for IMRT 5.1%, CRT 6.8%, and brachytherapy 5.3%. EtiologyThe cause and pathogenesis of osteoradionecrosis are far more complex than originally believed [6]. Recent theories for the pathogenesis of ORN have proposed that bone

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“…Cholesteatoma may occur as a result of chronic tympanic membrane perforation or fistula formation directly into the mastoid cavity. Labyrinthitis, 9,14 cerebrospinal fluid leak, 12,29,30 cerebellar abscess, 21 temporal lobe necrosis, 15 sigmoid sinus thrombosis, 4,14 and internal carotid artery aneurysm 4,31,32 have also been reported. Finally, in their series of 33 patients, Hao et al reported that tumor recurrence or radiation-associated malignancy was misdiagnosed as ORN in 21% of cases.…”

Section: Diagnosis and Classificationmentioning

confidence: 99%

“…Nearly 400 cases are described in the literature, predominantly through the publication of institutional case reports and retrospective case series. [4][5][6][7][8][9][10][11][12][13][14][15][16][17][18][19][20][21] Despite increasing awareness, ORNTB remains a debilitating and potentially lethal condition that continues to challenge patients and treating physicians.…”

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confidence: 99%

Radiation Necrosis of the Lateral Skull Base and Temporal Bone

et al. 2020

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Radiation therapy plays a critical role in the treatment of malignancies involving the head and neck. Although the therapeutic effects of ionizing radiation are achieved, normal tissues are also susceptible to injury and significant long-term sequelae. Osteoradionecrosis of the temporal bone (ORNTB) is among the many complications that can arise after therapy. ORNTB is a debilitating and potentially lethal condition that continues to challenge patients and treating physicians. Herein, we review the pathophysiology, presentation, work-up, and management of ORNTB.

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CSF Otorrhea Resulting from Osteoradionecrosis of the Temporal Bone in a Patient with Recurrent Meningioma

Cited by 14 publications

References 7 publications

Successful in a conservative treatment of osteoradionecrosis of the jaw: a case report and review of literature

Successful in a conservative treatment of osteoradionecrosis of the jaw: a case report and review of literature

Osteoradionecrosis of the Jaws

Radiation Necrosis of the Lateral Skull Base and Temporal Bone

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