CT findings of primary non-teratomatous germ cell tumors of the mediastinum—A report of 15 cases

Liu, Tian; Liu, Lizhi; Cui, Chunyan; Zhang, Weidong; Kuang, Ya-Ling

doi:10.1016/j.ejrad.2011.02.005

Cited by 23 publications

(14 citation statements)

References 15 publications

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“…Conversely, the median maximal diameter of mediastinal B-cell lymphoma was 11 cm on pretreatment CT in 51 patients, 22 patients with Hodgkin's lymphoma, 23 and 11 cm in 15 patients with mediastinal malignant germ cell tumour, respectively. 24 Fourth, there was no significant difference in ADC and other parameters between histological types. G € um € uş taş et al 18 recently reported that the mean ADC of malignant lesions was significantly lower than that of the benign masses; however, their study included 26 malignant lesions consisting of non-small cell lung cancers (NSCLCs; n¼11), lymphoma (n¼9), leukaemia (n¼2), oesophageal cancer (n¼2), malignant neurogenic tumour (n¼1), and metastatic lymphadenopathy from breast cancer (n¼1).…”

Section: Discussionmentioning

confidence: 92%

Anterior mediastinal solid tumours in adults: characterisation using dynamic contrast-enhanced MRI, diffusion-weighted MRI, and FDG-PET/CT

et al. 2015

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Section: Discussionmentioning

confidence: 92%

Anterior mediastinal solid tumours in adults: characterisation using dynamic contrast-enhanced MRI, diffusion-weighted MRI, and FDG-PET/CT

et al. 2015

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“…In our study among the 5 cases of mediastinal germ cell tumors, one case was teratoma and remaining were non teratomatous germ cell tumors of the mediastinum. Tian et al in their study concluded that the characteristic CT findings of primary non-teratomatous germ cell tumors of the mediastinum include bulky, ill-circumscribed, lobulated masses, heterogeneous attenuation with low-attenuation foci and calcification on non-enhanced CT images and heterogeneous enhancement after contrast administration [13]. Predictive power of CT diagnosis of mediastinal germ cell tumor against histopathology diagnosis was tried.…”

Section: Discussion and Resultsmentioning

confidence: 99%

Multidetector Computed Tomography Evaluation of Mediastinal Lesions with Histopathological Diagnosis

Arumugam¹,

Nazir²,

Rajasekar³

2015

OJRD

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The evaluation of mediastinal abnormalities is a challenging radiographical problem. Crosssectional imaging of the mediastinum by computed tomography now demonstrates precise anatomic details and is the imaging modality of choice for most mediastinal lesions. The following study was undertaken with the objectives of determining the mediastinal lesions affecting the mediastinum and to correlate the computed tomography findings with the histopathology reports. In this study, 50 patients clinically suspected with mediastinal mass lesions or who had chest radiograph with a suspicious mediastinal lesion were evaluated from October 2013 to September 2014. In our study, we used varying computed tomography features of each mediastinal pathology types to predict a histological diagnosis of mediastinal lesions. Most of the lesions could be predicted with good sensitivity, specificity and diagnostic accuracy.

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“…The choriocarcinoma grows rapidly, causing compression of the mediastinum and adjacent structures. Clinically, the patient may complain of shortness of breath, chest pain, cough, gynecomastia, or superior vena cava syndrome or be asymptomatic [3].…”

Section: Discussionmentioning

confidence: 99%

“…Anterior mediastinal choriocarcinoma is an extremely rare tumor [1,2], with a number of distinct CT characteristics [3,4]. Most importantly, the choriocarcinoma grows rapidly in the mediastinum, with bulky necrosis or degeneration.…”

Section: Introductionmentioning

confidence: 99%

Anterior Mediastinal Mass as the Initial Presentation of a Choriocarcinoma

Lee

Chan²

2016

Int J Radiol Med Imag

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A 43-year-old man presented with shortness of breath for 10 days and loss body weight in the past month. Chest palpation showed gynecomastia. Computed tomography scan of the chest showed a 14-cm necrotic mass at anterior mediastinum with extension to left upper lung and multiple nodules in both lungs. The beta human chorionic gonadotropin (β-HCG) level was elevated. The patient received ultrasound-guided biopsy of the anterior mediastinal mass. Histology revealed choriocarcinoma with trophoblastic differentiation and marked necrosis.

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CT findings of primary non-teratomatous germ cell tumors of the mediastinum—A report of 15 cases

Cited by 23 publications

References 15 publications

Anterior mediastinal solid tumours in adults: characterisation using dynamic contrast-enhanced MRI, diffusion-weighted MRI, and FDG-PET/CT

Anterior mediastinal solid tumours in adults: characterisation using dynamic contrast-enhanced MRI, diffusion-weighted MRI, and FDG-PET/CT

Multidetector Computed Tomography Evaluation of Mediastinal Lesions with Histopathological Diagnosis

Anterior Mediastinal Mass as the Initial Presentation of a Choriocarcinoma

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