Cu/Zn- and Mn-superoxide dismutase (SOD) from the copepod Tigriopus japonicus: Molecular cloning and expression in response to environmental pollutants

Identification and analysis of icCu/Zn-SOD, Mn-SOD and ecCu/Zn-SOD in superoxide dismutase multigene family of Pseudosciaena crocea

“…On the other hand, for the single gene, LycSOD1, LycSOD2 and LycSOD3 mRNA were all up-regulated after V. alginolyticus injection, which were similar to the expression of Cu/Zn-SOD from carp (C. auratus) after hexavalent chromium exposed [11], icCu/Zn-SOD from Sepiella maindroni after Vibrio harveyi challenge [8], icCu/Zn-SOD from Asian seabass (L. calcarifer) after Vibrio anguillarum infection [32], Mn-SOD from Penaeus monodon postlarvae after V. harveyi challenge [33], and ecCu/Zn-SOD from oriental river prawn (Macrobrachium nipponense) after injection with Aeromonas hydrophila [34]. SODs in ROS response could been induced by many physical, chemical, and biological factors, for example heat shock, heavy metals [35], B[a]P and TBT [36], pathogenic bacteria [37], etc., and Cu/Zn-SODs were considered as general stress responsive factors, whose expression at transcriptional and/or translational levels may be influenced by a variety of intracellular and environmental cues [1]. In this study LycSOD1 and LycSOD2 jumped to the peak at 24 h post-injection (around 9-fold and 8-fold respectively), whereas LycSOD3 got to the highest level at 48 h post-injection with lower RQ value (only about 4.2-fold) than those of LycSOD1 and LycSOD2.…”

Significance of adverse outcome pathways in biomarker-based environmental risk assessment in aquatic organisms

“…One recent study identified several aquatic invertebrates as potential model organisms due to their abundant populations and short life cycles (Dahms et al, 2011). Some invertebrate species that are potentially excellent model organisms in ecotoxicological risk assessment include (but are not limited to): water flea (D. magna), monogonont rotifer (Brachionus koreanus), and intertidal copepod (Tigriopus japonicus) (Choi, 2005;Raisuddin et al, 2007;Colbourne et al, 2011;Dahms et al, 2011;Kim et al, 2011;Rhee et al, 2011Rhee et al, , 2013b. The extensive genomics information available for these species may facilitate the simultaneous understanding of MOA and AO analyses on both the population and molecular levels in response to diverse classes of environmental pollutants.…”

Toxicological effects of benzo(a)pyrene, DDT and their mixture on the green mussel Perna viridis revealed by proteomic and metabolomic approaches

“…SOD is a typical antioxidant enzyme and plays a critical role in ROS (reactive oxygen species) scavenging (Hern andez-Nistal et al, 2002;Kim et al, 2011). In mussel, oxidative stress is a prominent feature of DDT toxicity, seen from the increase of gelsolin and actin, it ultimately generate complex cytoskeletal rearrangements in gill cell (Riva et al, 2011;Thrower et al, 2010).…”