Cultivation of the benthic microalga Prorocentrum lima for the production of diarrhetic shellfish poisoning toxins in a vertical flat photobioreactor

Wang, Shuai; Chen, Junhui; Li, Zhaoyong; Wang, Yanlong; Fu, Boqiang; Han, Xiaotian; Zheng, Li

doi:10.1016/j.biortech.2014.12.019

Cited by 43 publications

(54 citation statements)

References 22 publications

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“…Enriched nitrogen caused a continuous growth of algal cells, but the cellular toxin levels remained relatively low (≤8 pg/cell) [17]. This result, however, cannot be compared with that obtained by Varkitzi et al and Wang et al, who also varied the concentrations of phosphates [16,22]. …”

Section: Nutritional Factorsmentioning

confidence: 99%

“…However, the studies of the effect of these physical factors are very limited. Among these factors, only temperature, salinity and light have been studied [17,20,21,22,24,59,60]. …”

Section: Physical Factorsmentioning

confidence: 99%

“…P. Belizeanum exhibit the most favourable growth at 25 °C, but the cells undergo thermal stress at 28 °C [24]. According to the data shown in Table 3, the optimal temperature for the growth of both P. lima and P. belizeanum is 25 °C [20,22,24,60]. P. concavum and P. hoffmannianum grow optimally at relatively high temperatures—27 °C [60] and 29 °C [21], respectively.…”

Section: Physical Factorsmentioning

confidence: 99%

“…It is an alimentary intoxication caused by a suite of DSP toxins produced by the dinoflagellates Dinophysis and Prorocentrum [5,8,9,10]. The expression levels of biotoxins in these dinoflagellates are strongly affected by nutritional and environmental factors [11,12,13,14,15,16,17,18,19,20,21,22,23,24]. People who consume shellfish containing bioaccumulated DSP toxins may present with non-fatal gastrointestinal symptoms, such as nausea, vomiting, abdominal pain, and most commonly, diarrhoea within 12 h of consumption [25], because of a water imbalance caused by the hyperphosphorylation of ion channels in the epithelial cells lining the intestine [26].…”

Section: Introductionmentioning

confidence: 99%

“…Moreover, most DSP toxin studies concern benthic Prorocentrum spp. [13,14,15,16,17,18,19,20,21,22,23,24,58,59,60,61]. Following the development of a 3-step feeding protocol for Dinophysis spp.…”

Section: Introductionmentioning

confidence: 99%

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The Mechanism of Diarrhetic Shellfish Poisoning Toxin Production in Prorocentrum spp.: Physiological and Molecular Perspectives

Lee

Fong

et al. 2016

Toxins

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Diarrhetic shellfish poisoning (DSP) is a gastrointestinal disorder caused by the consumption of seafood contaminated with okadaic acid (OA) and dinophysistoxins (DTXs). OA and DTXs are potent inhibitors of protein phosphatases 2A, 1B, and 2B, which may promote cancer in the human digestive system. Their expression in dinoflagellates is strongly affected by nutritional and environmental factors. Studies have indicated that the level of these biotoxins is inversely associated with the growth of dinoflagellates at low concentrations of nitrogen or phosphorus, or at extreme temperature. However, the presence of leucine or glycerophosphate enhances both growth and cellular toxin level. Moreover, the presence of ammonia and incubation in continuous darkness do not favor the toxin production. Currently, studies on the mechanism of this biotoxin production are scant. Full genome sequencing of dinoflagellates is challenging because of the massive genomic size; however, current advanced molecular and omics technologies may provide valuable insight into the biotoxin production mechanism and novel research perspectives on microalgae. This review presents a comprehensive analysis on the effects of various nutritional and physical factors on the OA and DTX production in the DSP toxin-producing Prorocentrum spp. Moreover, the applications of the current molecular technologies in the study on the mechanism of DSP toxin production are discussed.

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Section: Nutritional Factorsmentioning

confidence: 99%

“…However, the studies of the effect of these physical factors are very limited. Among these factors, only temperature, salinity and light have been studied [17,20,21,22,24,59,60]. …”

Section: Physical Factorsmentioning

confidence: 99%

Section: Physical Factorsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

The Mechanism of Diarrhetic Shellfish Poisoning Toxin Production in Prorocentrum spp.: Physiological and Molecular Perspectives

Lee

Fong

et al. 2016

Toxins

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Developments and challenges in biodiesel production from microalgae: A review

Taparia

Mvss

Mehrotra

et al. 2015

Biotech and App Biochem

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The imminent depletion of fossil fuels and the surging global demand for renewable energy have led to the search for nonconventional energy sources. After a few decades of trial and error, the world is now testing the sources of the third generation of fossil fuels, which contain for most parts microalgae. With more than 80% oil content, being adaptable in growth parameters and highly versatile, microalgae are highly promising sources of biofuels in the present time. The present article makes a sweeping attempt to highlight the various methods employed for cultivation of microalgae, techniques to harvest and extract biomass from huge algal cultures, as well as their downstream production and processing procedures. The advantages, limitations, and challenges faced by each of them have been described to some extent. Major concerns pertaining to biofuels are supposed to be their environmental sustainability and economic viability along with their cost effectiveness. This would require a great deal of empirical data on existing systems and a great deal of optimization to generate a more robust one. We have concluded our article with a SWOT analysis of using algae for biodiesel production in a tabulated form.

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Microalgae as a potential source for biodiesel production: techniques, methods, and other challenges

Arenas

Palacio

Juantorena

et al. 2016

Int. J. Energy Res.

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Summary This paper reviews some of the most important aspects of microalgae as a potential source for biodiesel production. Microalgae are photosynthetic microorganisms that can grow rapidly in a variety of environments because of their unicellular or multicellular structure depending on the species. They have the advantage of self‐reproduction using solar energy and converting it into chemical energy via photosynthesis. This process concludes a full cycle in a few days, obtaining higher lipid yields than terrestrial crops. This review shows several techniques and some methodologies used in the biodiesel production process from microalgae as well as the challenges that must be overcome for large‐scale process and in bio‐refineries. Copyright © 2016 John Wiley & Sons, Ltd.

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Cultivation of the benthic microalga Prorocentrum lima for the production of diarrhetic shellfish poisoning toxins in a vertical flat photobioreactor

Cited by 43 publications

References 22 publications

The Mechanism of Diarrhetic Shellfish Poisoning Toxin Production in Prorocentrum spp.: Physiological and Molecular Perspectives

The Mechanism of Diarrhetic Shellfish Poisoning Toxin Production in Prorocentrum spp.: Physiological and Molecular Perspectives

Developments and challenges in biodiesel production from microalgae: A review

Microalgae as a potential source for biodiesel production: techniques, methods, and other challenges

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