“…A clinical implication of the environmental covariation is that some early‐life adversities (You, Albu, Lisenbardt, & Meagher, 2018) could increase liability to both anxiety and pain. Preclinical, genetically‐informed models of co‐occurring anxiety, pain, and early‐life adversities are beginning to provide leads about etiological mechanisms including gene‐environment interplay (Cittaro et al, 2016; Giannese et al, 2018), and new somatic treatments (Battaglia, Rossignol, Bachand, D'Amato, & De Koninck, 2019) that may constitute alternatives to current conceptualizations and treatments.…”