Cumulative effects of transcranial direct current stimulation on EEG oscillations and attention/working memory during subacute neurorehabilitation of traumatic brain injury

Assessing cortical synchronization during transcranial direct current stimulation: A graph-theoretical analysis

“…It is well established that tDCS alters the cortical neuronal firing rate, in a polarity-specific manner, specifically in terms of increased activity after anodal stimulation (Bindman et al, 1964;Purpura and McMurtry, 1965). Such an increase was actually coupled with decreased connectivity in the slow rhythms (i.e., theta), which could be related to local and global cortical excitability alterations (Mangia et al, 2014;Ulam et al, 2014). Although it is well established that theta rhythms increase during active movement and that theta-enhanced transmission across brain regions may be important for several different functions, such as facilitating the transfer of information from one brain region to another during different types of information processing (for a review, see Colgin, 2013), the role of theta frequency in the resting state condition is not clear.…”

“…To try to explain these alterations and to gain new insight into these mechanisms, tDCS and electroencephalographic (EEG) recordings have been used in sequential offline (Miniussi et al, 2012), and online tDCS-EEG approaches (e.g., Accornero et al, 2014;Baxter et al, 2014;Mangia et al, 2014), or in combination with other techniques (Hunter et al, NeuroImage xxx (2016) 2013), such as transcranial magnetic stimulation (TMS) (Pellicciari et al, 2013;Romero et al, 2014), magnetoencephalography (e.g., Garcia-Cossio et al, 2015) and electromyography (EMG) (Dutta et al, 2014). Until now, studies using EEG have shown how the tDCS induces polarity-specific on brain activity oscillations in different frequency bands (Kirov et al, 2009;Miller et al, 2015;Notturno et al, 2014;Song et al, 2014;Spitoni et al, 2013;Ulam et al, 2014). However, a network approach could be used to obtain a better understanding of the ongoing effects induced by neuromodulation (Bortoletto et al, 2015;Luft et al, 2014) and to capture brain functions in a multidimensional manner (i.e., from a network prospective).…”

Does transcranial direct current stimulation enhance cognitive and motor functions in the ageing brain? A systematic review and meta- analysis

“…As a consequence, tDCS protocols have been applied to a number of brain sites including the primary motor cortex (M1), dorsolateral prefrontal cortex, parietal cortex, inferior frontal gyrus, as well as the cerebellum while investigating stimulation effects on a variety of cognitive and motor functions (Brunoni and Vanderhasselt, 2014;Ferrucci and Priori, 2014;Shin et al, 2015). Further, tDCS has been applied to a wide range of neurological disorders including stroke (Marquez et al, 2015), Parkinson's disease (Benninger et al, 2010), chronic pain (Fregni et al, 2006), depression (Arul-Anandam and Loo, 2009), and traumatic brain injury (Ulam et al, 2014).…”

Chronic Electrical Stimulation Promotes the Excitability and Plasticity of ESC-derived Neurons following Glutamate-induced InhibitionIn vitro

“…Transcranial DCS (tDCS) has been demonstrated to mediate therapeutic outcomes 1,3,4 in depression [5][6][7] , dementia 8,9 , pain 10,11 and central nervous system injury [12][13][14] . In addition, tDCS applications extend to neuroprosthetics including improving working memory 15 , motor and declarative learning [16][17][18][19] and decision making/addiction [20][21][22][23] .…”