CuO nanoflakes anchored polythiophene nanocomposite: Voltammetric detection of L-Tryptophan

GunaVathana, S. Dheepthi; Wilson, J.; Prashanthi, R.; Péter, Á.

doi:10.1016/j.inoche.2020.108398

Cited by 21 publications

(10 citation statements)

References 55 publications

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“…Conducting polymers are among the most important materials used to support the metal-oxide nanoparticles (MOÀ NPs). Previous studies revealed that organic-inorganic composites elaborated by the addition of polymers, such as polypyrrol [39,40], polythiophene [41], porphyrin [42] and polyethylene glycol [43] to the metal oxide nanoparticles, are more sensitive to detect biomolecules than MOÀ NPs modified electrodes. Polyaniline is a p-type conducting polymer and one of the best candidates.…”

Section: Introductionmentioning

confidence: 99%

Highly Sensitive Enzyme‐free Sensor Based on a Carbon Paste Electrode Modified with Binary Zinc Oxide/Polyaniline Nanocomposites for Dopamine, Ascorbic Acid and Uric Acid Sensing

Kadri

Bekri-Abbess²,

Herrasti

2022

Electroanalysis

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Hybrid composites ZnO/PANI were facily synthesized by a sonication process at room temperature. This procedure is non-expensive, time/energy saving and environmentally safe. The as-prepared ZnO/PANI were characterized by FTIR, UV-vis spectroscopies and SEM in order to investigate the structure and morphology of the studied composites. The samples were used to modify carbon paste electrode (CPE) in order to develop electrochemical biosensors (ZnO/PANI/CPE). The sensing properties of the nanoparticles were evaluated for dopamine, ascorbic acid and uric acid non-enzymatic detection. The effect of percentage of polyaniline in the composites and the effect of calcination on the biosensor's response were also examined in the present study. It was revealed that the existence of PANI in ZnO/PANI/CPE largely enhanced the electroactive surface area and therefore the sensitivity for electrochemical sensing. A good electrochemical behavior was noted for ZnO/40 wt% PANI-cal/ CPE modified electrode toward DA, AA and UA oxidation. The electroactive surface area of the previously mentioned modified electrode (0.235 cm 2 ) was two times higher than that of the bare electrode (0.117 cm 2 ). The liner relationships between current intensities and concentrations were found to be 0.01-1.4 mM, 0.1-1.3 mM and 0.01-0.12 mM, with detection limit of 0.029 mM, 0.063 mM and 0.007 mM, for DA, AA and UA respectively. In the mixtures of ascorbic acid (AA), dopamine (DA) uric acid (UA) and glucose (Glu) the sensor showed high selectivity of DA with low interference of ascorbic acid by a current change of 14 %. The asprepared ZnO/PANI/CPE biosensor displayed a good reproducibility and stability.

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Section: Introductionmentioning

confidence: 99%

Highly Sensitive Enzyme‐free Sensor Based on a Carbon Paste Electrode Modified with Binary Zinc Oxide/Polyaniline Nanocomposites for Dopamine, Ascorbic Acid and Uric Acid Sensing

Kadri

Bekri-Abbess²,

Herrasti

2022

Electroanalysis

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“…Following the discovery of CPs, Alan J. Heeger, Alan G. MacDiarmid, and Hideki Shirakawa received the Nobel Prize for Chemistry in 2000 [96]. The CPs most frequently encountered in scientific research are PPy [97][98][99][100][101], PANI [102][103][104][105], PEDOT [46,[106][107][108][109], PT [110][111][112][113], and polyacetylene [114][115][116], the chemical structures of which are shown in Figure 3. This type of polymer is usually obtained by electrochemical polymerization, a process that takes place in a solution that includes the solvent, the polymerizable monomer, and the electrolyte.…”

Section: Cps and Mips Used To Determine Phe Tyr And Tryptmentioning

confidence: 99%

A Review of Sensors and Biosensors Modified with Conducting Polymers and Molecularly Imprinted Polymers Used in Electrochemical Detection of Amino Acids: Phenylalanine, Tyrosine, and Tryptophan

Dinu

Apetrei

2022

IJMS

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Recently, the studies on developing sensors and biosensors—with an obvious interdisciplinary character—have drawn the attention of many researchers specializing in various fundamental, but also complex domains such as chemistry, biochemistry, physics, biophysics, biology, bio-pharma-medicine, and bioengineering. Along these lines, the present paper is structured into three parts, and is aimed at synthesizing the most relevant studies on the construction and functioning of versatile devices, of electrochemical sensors and biosensors, respectively. The first part presents examples of the most representative scientific research focusing on the role and the importance of the phenylalanine, tyrosine, and tryptophan amino acids, selected depending on their chemical structure and their impact on the central nervous system. The second part is dedicated to presenting and exemplifying conductor polymers and molecularly imprinted polymers used as sensitive materials in achieving electrochemical sensors and biosensors. The last part of the review analyzes the sensors and biosensors developed so far to detect amino acids with the aid of conductor polymers and molecularly imprinted polymers from the point of view of the performances obtained, with emphasis on the detection methods, on the electrochemical reactions that take place upon detection, and on the electroanalytical performances. The present study was carried out with a view to highlighting, for the benefit of specialists in medicine and pharmacy, the possibility of achieving and purchasing efficient devices that might be used in the quality control of medicines, as well as in studying and monitoring diseases associated with these amino acids.

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“…In 2021, GCE was modified with a nanocomposite of CuO nanoflakes anchored with polythiophene (PT-CuO/ GCE). 118 Despite the aforementioned exciting features of copper oxides in sensing, it has few limitations such as low conductivity and aggregation. To improve these shortcomings, a CuO-PT nanocomposite was prepared.…”

Section: Dovepressmentioning

confidence: 99%

Recent Advances in Electrochemical and Optical Sensors for Detecting Tryptophan and Melatonin

Khan¹,

Hong²,

Lee³

et al. 2021

IJN

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Tryptophan and melatonin are pleiotropic molecules, each capable of influencing several cellular, biochemical, and physiological responses. Therefore, sensitive detection of tryptophan and melatonin in pharmaceutical and human samples is crucial for human wellbeing. Mass spectrometry, high-performance liquid chromatography, and capillary electrophoresis are common methods for both tryptophan and melatonin analysis; however, these methods require copious amounts of time, money, and manpower. Novel electrochemical and optical detection tools have been subjects of intensive research due to their ability to offer a better signal-to-noise ratio, high specificity, ultra-sensitivity, and wide dynamic range. Recently, researchers have designed sensitive and selective electrochemical and optical platforms by using new surface modifications, microfabrication techniques, and the decoration of diverse nanomaterials with unique properties for the detection of tryptophan and melatonin. However, there is a scarcity of review articles addressing the recent developments in the electrochemical and optical detection of tryptophan and melatonin. Here, we provide a critical and objective review of high-sensitivity tryptophan and melatonin sensors that have been developed over the past six years (2015 onwards). We review the principles, performance, and limitations of these sensors. We also address critical aspects of sensitivity and selectivity, limit and range of detection, fabrication process and time, durability, and biocompatibility. Finally, we discuss challenges related to tryptophan and melatonin detection and present future outlooks.

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CuO nanoflakes anchored polythiophene nanocomposite: Voltammetric detection of L-Tryptophan

Cited by 21 publications

References 55 publications

Highly Sensitive Enzyme‐free Sensor Based on a Carbon Paste Electrode Modified with Binary Zinc Oxide/Polyaniline Nanocomposites for Dopamine, Ascorbic Acid and Uric Acid Sensing

Highly Sensitive Enzyme‐free Sensor Based on a Carbon Paste Electrode Modified with Binary Zinc Oxide/Polyaniline Nanocomposites for Dopamine, Ascorbic Acid and Uric Acid Sensing

A Review of Sensors and Biosensors Modified with Conducting Polymers and Molecularly Imprinted Polymers Used in Electrochemical Detection of Amino Acids: Phenylalanine, Tyrosine, and Tryptophan

Recent Advances in Electrochemical and Optical Sensors for Detecting Tryptophan and Melatonin

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