Curcumin-loaded protein imprinted mesoporous nanosphere for inhibiting amyloid aggregation

Hou, Tongtong; Zhang, Nan; Yan, Chaoren; Ding, Minling; Niu, Huizhe; Guan, Ping; Hu, Xiaoling

doi:10.1016/j.ijbiomac.2022.08.185

Cited by 10 publications

(2 citation statements)

References 65 publications

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“…Another benefit is to enhance the colloidal stability of the MSNs. The most commonly employed are poly( N -isopropylacrylamide) (pNIPAM) and several analogs, as well as polyethylene glycol acrylates (PEG acrylates) or natural biopolymers agar and agarose, since they suffer a degradation or alteration of the polymer network that provokes drug releases as a consequence of induced localized hyperthermia [ 72 , 73 , 74 , 75 , 76 , 77 , 78 ].…”

Section: Engineering Of Msns As Stimuli-responsive Drug Delivery Systemsmentioning

confidence: 99%

Natural Biopolymers as Smart Coating Materials of Mesoporous Silica Nanoparticles for Drug Delivery

et al. 2023

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In recent years, the functionalization of mesoporous silica nanoparticles (MSNs) with different types of responsive pore gatekeepers have shown great potential for the formulation of drug delivery systems (DDS) with minimal premature leakage and site-specific controlled release. New nanotechnological approaches have been developed with the objective of utilizing natural biopolymers as smart materials in drug delivery applications. Natural biopolymers are sensitive to various physicochemical and biological stimuli and are endowed with intrinsic biodegradability, biocompatibility, and low immunogenicity. Their use as biocompatible smart coatings has extensively been investigated in the last few years. This review summarizes the MSNs coating procedures with natural polysaccharides and protein-based biopolymers, focusing on their application as responsive materials to endogenous stimuli. Biopolymer-coated MSNs, which conjugate the nanocarrier features of mesoporous silica with the biocompatibility and controlled delivery provided by natural coatings, have shown promising therapeutic outcomes and the potential to emerge as valuable candidates for the selective treatment of various diseases.

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Section: Engineering Of Msns As Stimuli-responsive Drug Delivery Systemsmentioning

confidence: 99%

Natural Biopolymers as Smart Coating Materials of Mesoporous Silica Nanoparticles for Drug Delivery

et al. 2023

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“…Thioflavin T (ThT) can bind to the b-sheet structure and emit fluorescence. 34 Fig. 2A and B shows the inhibitory effect of PEG@MIL-101 and AuNPs@ PEG@MIL-101 on Ab 40 aggregation.…”

Section: Impact Of Aunps@peg@mil-101 On the Fibrillation And Morpholo...mentioning

confidence: 99%

Electrostatic assembly of gold nanoparticle and metal–organic framework nanoparticles attenuates amyloid β aggregate-mediated neurotoxicity

et al. 2023

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Controlled preparation of tannic acid–derived carbonized dots and their use to inhibit amyloid aggregation and promote aggregate disaggregation

Cao,

Fan,

Shao

et al. 2024

Microchim Acta

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Curcumin-loaded protein imprinted mesoporous nanosphere for inhibiting amyloid aggregation

Cited by 10 publications

References 65 publications

Natural Biopolymers as Smart Coating Materials of Mesoporous Silica Nanoparticles for Drug Delivery

Natural Biopolymers as Smart Coating Materials of Mesoporous Silica Nanoparticles for Drug Delivery

Electrostatic assembly of gold nanoparticle and metal–organic framework nanoparticles attenuates amyloid β aggregate-mediated neurotoxicity

Controlled preparation of tannic acid–derived carbonized dots and their use to inhibit amyloid aggregation and promote aggregate disaggregation

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