2015
DOI: 10.1016/j.ijpharm.2015.05.008
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Curcumin–piperine mixtures in self-microemulsifying drug delivery system for ulcerative colitis therapy

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Cited by 89 publications
(24 citation statements)
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“…Higher loading of Cur on GP was achieved as compared to other recently reported delivery cargos2425262728293031 (Supplementary Table S3). Even by utilizing GO, only 208 wt.% was obtained24 achieving only half of the loading capacity as compared to our current approach.…”
Section: Resultsmentioning
confidence: 76%
“…Higher loading of Cur on GP was achieved as compared to other recently reported delivery cargos2425262728293031 (Supplementary Table S3). Even by utilizing GO, only 208 wt.% was obtained24 achieving only half of the loading capacity as compared to our current approach.…”
Section: Resultsmentioning
confidence: 76%
“…A combination of curcumin with conventional anticancer agents may lead to better treatment outcomes for tumour MDR therapy. Curcumin has been co-administered with various potent chemotherapeutic drugs, such as cisplatin, doxorubicin, paclitaxel, etc., as part of the treatment modalities for many multidrug-resistant cancers 19 20 21 22 .…”
mentioning
confidence: 99%
“…Shoba et al [41] demonstrated that 20 mg of piperine administered concomitantly with 2 g of curcumin increases the bioavailability of curcumin 20-fold in humans. One experimental study by Li et al [42], using CUR-PIP-SMEDDS (an emulsified curcumin and piperine formulation), reported that the administration of this formulation through an enema in rats had an effect similar to 5-ASA in maintaining remission in dextran sulfate sodium DSS-induced colitis. As a substance that inhibits the metabolism of several active compounds, piperine may cause toxicity when associated with some drugs [43].…”
Section: Discussionmentioning
confidence: 99%