Current Advances in Hypertrophic Scar and Keloid Management

Barone, Natasha; Safran, Tyler; Vorstenbosch, Joshua; Davison, Peter G.; Cugno, Sabrina; Murphy, Amanda

doi:10.1055/s-0041-1731461

Cited by 44 publications

(34 citation statements)

References 117 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Unfortunately, timeliness is not always possible, as in the case described in this study, where healing times were very long. In addition, there are people who have old scars and/or who have not benefited from the various treatments performed [ 44 , 45 ]. In these cases, a long time passes after the initial injury.…”

Section: Discussionmentioning

confidence: 99%

“…There are numerous more or less invasive treatments aimed at improving residual aesthetic stigmatizations and facial dysfunctions ( Table 1 , [ 25 , 26 , 27 , 28 , 29 , 30 , 31 , 32 , 33 , 34 , 35 , 36 , 37 , 38 , 39 , 40 , 41 , 42 , 43 ]), but an optimal treatment has not yet been identified [ 44 , 45 ]. In fact, although many interventions appear promising, sometimes the results reported in the literature are conflicting [ 32 , 33 , 34 , 35 ], or interventions suitable for some types of scars are not effective for others [ 29 , 43 , 44 , 45 ]. This may depend on the extreme variability of individual situations, for each of which a personalized medical-surgical-rehabilitation path should be identified.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Vacuum and Electromagnetic Fields Treatment to Regenerate a Diffuse Mature Facial Scar Caused by Sulfuric Acid Assault

Veronese

Brunetti²,

Minichino³

et al. 2022

Bioengineering

View full text Add to dashboard Cite

Acid attacks are on the rise, and they cause extensive and deep burns, especially on the face. The treatments used to improve the aesthetic, functional and social impact of non-acid scars do not always prove useful for acid scars. This article reports the case of a woman with an extended, mature, acid facial scar, caused by sulfuric acid assault, treated with a recent new procedure that combines the application of vacuum and electromagnetic fields. Before and after the treatment, the aesthetic appearance, and motor function of the face and neck were evaluated, as well as the level of hydration, the amount of sebum, the elasticity, and the pH of the skin. The improvements highlighted after the treatment of the aesthetic and functional characteristics of the face and neck, and of the physical parameters of the skin seemed to indicate that this particular treatment induces tissue regeneration, even in the nerve component. However, it is evident that the rehabilitation pathways of facial wounds and scars must be personalized, and must include continuous psychological support for the patient.

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Vacuum and Electromagnetic Fields Treatment to Regenerate a Diffuse Mature Facial Scar Caused by Sulfuric Acid Assault

Veronese

Brunetti²,

Minichino³

et al. 2022

Bioengineering

View full text Add to dashboard Cite

show abstract

“…Hence, the model could help the diagnosis of solar elastosis following long-term exposure. 39 Beyond healthy skin, this automatic and quantified analysis of in vivo LC-OCT images could also be applied for clinical investigations to improve understanding and/or diagnosis of skin disorders targeting the dermis, such as stretch marks, 40 scars from different origins, 41,42 or skin fibrosis. 43 In conclusion, the results confirm that a deep learning technique can provide an efficient and objective assessment of the quality of the dermal matrix, thus reducing the workload of experts.…”

Section: Discussionmentioning

confidence: 99%

Utilizing deep learning for dermal matrix quality assessment on in vivo line‐field confocal optical coherence tomography images

Breugnot

Rouaud-Tinguely

Gilardeau

et al. 2022

Skin Research and Technology

View full text Add to dashboard Cite

Background Line‐field confocal optical coherence tomography (LC‐OCT) is an imaging technique providing non‐invasive “optical biopsies” with an isotropic spatial resolution of ∼1 μm and deep penetration until the dermis. Analysis of obtained images is classically performed by experts, thus requiring long and fastidious training and giving operator‐dependent results. In this study, the objective was to develop a new automated method to score the quality of the dermal matrix precisely, quickly, and directly from in vivo LC‐OCT images. Once validated, this new automated method was applied to assess photo‐aging‐related changes in the quality of the dermal matrix. Materials and methods LC‐OCT measurements were conducted on the face of 57 healthy Caucasian volunteers. The quality of the dermal matrix was scored by experts trained to evaluate the fibers’ state according to four grades. In parallel, these images were used to develop the deep learning model by adapting a MobileNetv3‐Small architecture. Once validated, this model was applied to the study of dermal matrix changes on a panel of 36 healthy Caucasian females, divided into three groups according to their age and photo‐exposition. Results The deep learning model was trained and tested on a set of 15 993 images. Calculated on the test data set, the accuracy score was 0.83. As expected, when applied to different volunteer groups, the model shows greater and deeper alteration of the dermal matrix for old and photoexposed subjects. Conclusions In conclusion, we have developed a new method that automatically scores the quality of the dermal matrix on in vivo LC‐OCT images. This accurate model could be used for further investigations, both in the dermatological and cosmetic fields.

show abstract

“…After surgery, there is a high recurrence risk of about 100% for keloids, which do not diminish over time [3]. Both scars are unattractive and linked to a decline in quality of life, physical condition, and mental health [4]. In the Indian community, 50 patients were diagnosed with 71 keloids, and 48% of those cases had ear keloids because ear piercing is a common custom there [5].…”

Section: Introductionmentioning

confidence: 99%

Keloids: A Review of the Diseases, Causes, and Current Treatments

Anirudh¹,

Gomathi²,

Sujatha³

et al. 2022

JPRI

View full text Add to dashboard Cite

Keloids are benign tumors that grow as a result of excessive collagen release from overexpressed fibroblasts. Keloids and hypertrophic scars are distinguished by the fact that keloids develop beyond the site of the original lesion, but hypertrophic scars do not. It is still unclear why this mechanism operates, mainly when aberrant scarring occurs. Despite several treatments' availability, the keloids' recurrence rate remains high. Here, we summarize recent narrative reviews, systematic reviews, and meta-analyses to give a general overview of the condition, its underlying causes, and available therapies for keloids. To undertake a comprehensive investigation of the disease, over 100 publications were reviewed utilizing Google Scholar and Pubmed. We also shed light on using phytochemicals as a natural alternative to prevent keloid scarring, which occurs when the body responds abnormally to external injuries by producing scar tissue. We also summarize the available current treatments.

show abstract

Current Advances in Hypertrophic Scar and Keloid Management

Cited by 44 publications

References 117 publications

Vacuum and Electromagnetic Fields Treatment to Regenerate a Diffuse Mature Facial Scar Caused by Sulfuric Acid Assault

Vacuum and Electromagnetic Fields Treatment to Regenerate a Diffuse Mature Facial Scar Caused by Sulfuric Acid Assault

Utilizing deep learning for dermal matrix quality assessment on in vivo line‐field confocal optical coherence tomography images

Keloids: A Review of the Diseases, Causes, and Current Treatments

Contact Info

Product

Resources

About