Current Developments and Future Trends in Solid-phase Microextraction Techniques for Pharmaceutical and Biomedical Analyses

Kataoka, Hiroyuki

doi:10.2116/analsci.27.893

Cited by 97 publications

(40 citation statements)

References 150 publications

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“…As a potential analytical method, SPME is extensively employed in the analysis for food, aromatic hydrocarbon, pharmaceutical, metallic, biological, forensic, and environmental samples due to avoid of using excess organic solvents, short analysis time and reusability, etc . Now a day, various new methods such as in‐tube, stir‐bar sorptive, thin‐film, in‐tip, and syringe SPME have been investigated . However, limited efficiency, high back pressure, low stability are major drawbacks of such materials.…”

Section: Introductionmentioning

confidence: 99%

Polystyrene‐Supported Core–Shell Beads with Aluminium MOF Coating for Extraction of Organic Pollutants

Kuo

Pal

et al. 2019

Chemistry An Asian Journal

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Aluminium-based metal-organic framework (MOF) coatings on polystyrene bead surfaces were easily synthesized by reacting an intermediate metal hydroxide coating with an organic linker.S everal different sizes of polystyrene beads were coated with aluminium metal hydroxide to construct Al@PS core-shell bead materials. The activated Al@PS core-shell beads were involved to make ah omogenous MOF-basedl ayer in the presence of the organic linker.B y using different sizes of the PS support the size of MOFs on the PS composites could be fine-tuned under specific reaction conditions. MOF-coated core-shell bead materials (Al-1,4-NDC@PS and MIL-53(Al)@PS) were characterized using variousa nalytical techniques. Al-1,4-NDC@PS and MIL-53(Al)@PS were evaluated fors olid-phase microextraction (SPME) of hydrophobic polycyclic aromatic hydrocarbons (PAHs) and hydrophilic non-steroidal anti-inflammatory drugs (NSAIDs),r espectively.A l-1,4-NDC@PS-1000 displayed high extraction recoveries ranging from 79.2 %t o9 9.8 %i n the SPME of PAHs. Meanwhile, MIL-53(Al)@PS-1000 showed 85.9-99.0 %e xtraction recoveries in the SPME of NSAIDs. These results show that the proposed approachh olds potential to extract organic analytes on an industrial scale.

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Section: Introductionmentioning

confidence: 99%

Polystyrene‐Supported Core–Shell Beads with Aluminium MOF Coating for Extraction of Organic Pollutants

Kuo

Pal

et al. 2019

Chemistry An Asian Journal

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“…We recently developed in-tube SPME methods, coupled with LC-MS/MS, to determine urinary concentrations of 8-IP [46] and 8-OHdG [47]. The details of the in-tube SPME technique and its applications have been summarized in several reviews [48][49][50]. This study describes our development of an automated online in-tube SPME-LC-MS/MS with negative/positive ion-switching ESI for simultaneous determination of 8-IP, 8-OHdG, and 3-NT in urine samples.…”

Section: Introductionmentioning

confidence: 99%

Simultaneous analysis of multiple urinary biomarkers for the evaluation of oxidative stress by automated online in‐tube solid‐phase microextraction coupled with negative/positive ion‐switching mode liquid chromatography–tandem mass spectrometry

Saito

Hamano

Kataoka

2018

J of Separation Science

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This study described an automated online method for the simultaneous determination of 8-isoprostane, 8-hydroxy-2'-deoxyguanosine, and 3-nitro-l-tyrosine in human urine. The method involves in-tube solid-phase microextraction using a Carboxen 1006 PLOT capillary column as an extraction device, followed by liquid chromatography with tandem mass spectrometry using a CX column and detection in the negative/positive switching ion-mode by multiple reaction monitoring. Using their stable isotope-labeled internal standards, each of these oxidative stress biomarkers showed good linearity from 0.02 to 2.0 ng/mL. Their detection limits (S/N = 3) were 3.4-21.5 pg/mL, and their intra- and inter-day precisions (relative standard deviations) were >3.9 and 6.5% (n = 5), respectively. This method was applied successfully to the analysis of urine samples, without any other pretreatment and interference peaks.

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“…The conventional TD process enables a sensitive and fully-automated analysis, although relatively expensive specially-designed instruments are necessary. [21][22][23] Solid-phase microextraction (SPME) is a simple and solvent-free sample preparation technique, 24,25 which is based on the equilibrium between the sample matrix and the extraction phase that is immobilized on a solid support. This method has been widely applied to the analysis of VOCs; however, the extraction medium consisted of a fused-silica rod, which is quite fragile.…”

Section: Introductionmentioning

confidence: 99%

Needle-type Extraction Device Designed for Rapid and Sensitive Analysis in Gas Chromatography

Ueta

Saito

2014

ANAL. SCI.

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Current Developments and Future Trends in Solid-phase Microextraction Techniques for Pharmaceutical and Biomedical Analyses

Cited by 97 publications

References 150 publications

Polystyrene‐Supported Core–Shell Beads with Aluminium MOF Coating for Extraction of Organic Pollutants

Polystyrene‐Supported Core–Shell Beads with Aluminium MOF Coating for Extraction of Organic Pollutants

Simultaneous analysis of multiple urinary biomarkers for the evaluation of oxidative stress by automated online in‐tube solid‐phase microextraction coupled with negative/positive ion‐switching mode liquid chromatography–tandem mass spectrometry

Needle-type Extraction Device Designed for Rapid and Sensitive Analysis in Gas Chromatography

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