Current endovascular treatment options of dural venous sinus thrombosis: a review of the literature

Gala, Nihar B.; Agarwal, Nitin; Barrese, James C.; Gandhi, Chirag D.; Prestigiacomo, Charles J.

doi:10.1136/neurintsurg-2011-010117

Cited by 34 publications

(23 citation statements)

References 100 publications

(55 reference statements)

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“…SVT'nin tedavisinde son zamanlarda trombolitik tedavi kullanılmaya başlamış olsa da klasik tedavisi antikoagülanlardır (8). Her iki grup ilaçların etkinlikleri sınırlı olmasının yanında Lökosit ve Nötrofil Yüksekliğinin Serebral Venöz Trombozda Önemi kanama gibi ciddi komplikasyonları söz konusudur.…”

Section: Discussionunclassified

The prognostic value of increased leukocyte and neutrophil counts in the early phase of cerebral venous sinus thrombosis

Kamışlı¹,

Kamışlı²,

Gönüllü³

et al. 2012

Türk Beyin Damar Hast Derg

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Section: Discussionunclassified

The prognostic value of increased leukocyte and neutrophil counts in the early phase of cerebral venous sinus thrombosis

Kamışlı¹,

Kamışlı²,

Gönüllü³

et al. 2012

Türk Beyin Damar Hast Derg

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“…Unique to DVST, younger individuals, less than 50 years of age, are affected and has an average rate of death or dependency of fifteen percent (4,5). Women are more commonly diagnosed with DVST than men (6,7).…”

mentioning

confidence: 99%

New Developments in the Pathophysiology, Workup, and Diagnosis of Dural Venous Sinus Thrombosis (DVST) and a Systematic Review of Endovascular Treatments

Konakondla¹,

Schirmer²,

Li³

et al. 2017

Aging and disease

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Dural venous sinus thrombosis (DVST) is a rare cause of stroke, which typically affects young women. The importance of identifying pre-disposing factors that lead to venous stasis lies in the foundation of understanding the etiology, pathophysiology and clinical presentation. The precise therapeutic role of interventional therapies is not fully understood though the current data do suggest potential applications. The aim of the study was to perform a systematic review and meta-analysis to evaluate the utility of and short-term 30-day survival after endovascular therapy for patients with DVST. Standard PRISMA guidelines were followed. Data sources included PubMed keywords and phrases, which were also incorporated into a MeSH search to yield articles indexed in Medline over a 5-year period. All RCTs, observational cohort studies, and administrative registries comparing or reporting DVST were included. Sixty-six studies met inclusion criteria. 35 articles investigating treatment in a summation of 10,285 patients were eligible for data extraction and included in the review of treatment modalities. A total of 312 patients were included for statistical analysis. All patients included received endovascular intervention with direct thrombolysis, mechanical thrombectomy or both. 133 (42.6%) patients were documented to have a neurologic decline, which prompted endovascular intervention. All patients who had endovascular interventions were those who were started on and failed systemic anticoagulation. 44 patients were reported to have intracranial hemorrhages after intervention. Regardless of systemic anticoagulation, patients were still reported to have complications of VTE and PE. Primary outcome at 3-6 month follow up revealed mRS<1 in 224 patients. DVST presents with many diagnostic and therapeutic challenges. The utility of invasive interventions such as local thrombolysis and mechanical thrombectomy is not fully understood. It is exceedingly difficult to conduct large randomized trials for this low incidence disease process with large pathophysiological heterogeneity.

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“…Hence, there are no proven treatment guidelines. However, according to a retrospective review, the mortality rate for patients treated with either IV heparin or local thrombolytics was 13% compared with 48% in untreated patients 12 and local thrombolysis has better follow-up results in severe cases 15 .…”

Section: Resultsmentioning

confidence: 99%

Endovascular Treatment of Acute Thrombosis of Cerebral Veins and Sinuses

et al. 2014

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Current endovascular treatment options of dural venous sinus thrombosis: a review of the literature

Cited by 34 publications

References 100 publications

The prognostic value of increased leukocyte and neutrophil counts in the early phase of cerebral venous sinus thrombosis

The prognostic value of increased leukocyte and neutrophil counts in the early phase of cerebral venous sinus thrombosis

New Developments in the Pathophysiology, Workup, and Diagnosis of Dural Venous Sinus Thrombosis (DVST) and a Systematic Review of Endovascular Treatments

Endovascular Treatment of Acute Thrombosis of Cerebral Veins and Sinuses

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