Search citation statements
Paper Sections
Citation Types
Year Published
Publication Types
Relationship
Authors
Journals
Aim. To study the prevalence of gastroesophageal reflux disease (GERD) and erosive-ulcerative lesions of the gastroduodenal zone and their association among various age groups of Siberian schoolchildren.Material and methods. In order to identify gastrointestinal complaints, a cross-sectional survey of schoolchildren at the age of 7–17 years in the settlements of the Republic of Tyva, Evenkia and Buryatia was conducted. In total, 1535 schoolchildren were examined (7–11 years old — 855 and 12–17 years old — 680 people) in Tyva, 790 (7–11 years old — 333 and 12–17 years old — 457 people) in Buryatia and 1369 (7–11 years old — 633 and 12–17 years old — 736 people) in Evenkia. GERD diagnosis in schoolchildren was based on the presence of heartburn complaints following the worldwide consensus on the GERD definition among the pediatric population. An esophagogastroduodenoscopy (283 children in Tyva, 110 in Buryatia and 205 in Evenkia) was performed by random selection in the age groups of schoolchildren with gastrointestinal complaints in each region.Results. The GERD prevalence among schoolchildren in Siberia was 6.4 %. At the same time, the clinical signs of GERD were mainly noted in schoolchildren of the older age group: at the age of 12–17 years old in 9.4 % of cases, at the age of 7–11 years old in 3.2 % (p = 0.01) of cases. The indicators in the Republic of Tyva were 9.5 %, which is higher than those for schoolchildren in Buryatia (4.1 %; p = 0.01) and Evenkia (4.2 %; p = 0.01). The disease was represented mainly by a non-erosive form. In younger schoolchildren, the non-erosive form of GERD is diagnosed much less frequently and only in Tyva (14.0 %). Erosive esophagitis was diagnosed in 4 cases (0.7 %), 3 of which were in older schoolchildren in Tyva. Erosive-ulcerative diseases of the stomach and duodenum were recorded, to a greater extent, in older children, and largely in Tyva. A more frequent combination of GERD and erosive-ulcerative lesions of the gastroduodenal zone was noted in Tyva, particularly in the older age group.Conclusion. In Siberian schoolchildren, an association of erosive and ulcerative lesions of the mucosa of the gastroduodenal zone with GERD was established, the severity of which has age-related features and is closely related to the region of residence.
Aim. To study the prevalence of gastroesophageal reflux disease (GERD) and erosive-ulcerative lesions of the gastroduodenal zone and their association among various age groups of Siberian schoolchildren.Material and methods. In order to identify gastrointestinal complaints, a cross-sectional survey of schoolchildren at the age of 7–17 years in the settlements of the Republic of Tyva, Evenkia and Buryatia was conducted. In total, 1535 schoolchildren were examined (7–11 years old — 855 and 12–17 years old — 680 people) in Tyva, 790 (7–11 years old — 333 and 12–17 years old — 457 people) in Buryatia and 1369 (7–11 years old — 633 and 12–17 years old — 736 people) in Evenkia. GERD diagnosis in schoolchildren was based on the presence of heartburn complaints following the worldwide consensus on the GERD definition among the pediatric population. An esophagogastroduodenoscopy (283 children in Tyva, 110 in Buryatia and 205 in Evenkia) was performed by random selection in the age groups of schoolchildren with gastrointestinal complaints in each region.Results. The GERD prevalence among schoolchildren in Siberia was 6.4 %. At the same time, the clinical signs of GERD were mainly noted in schoolchildren of the older age group: at the age of 12–17 years old in 9.4 % of cases, at the age of 7–11 years old in 3.2 % (p = 0.01) of cases. The indicators in the Republic of Tyva were 9.5 %, which is higher than those for schoolchildren in Buryatia (4.1 %; p = 0.01) and Evenkia (4.2 %; p = 0.01). The disease was represented mainly by a non-erosive form. In younger schoolchildren, the non-erosive form of GERD is diagnosed much less frequently and only in Tyva (14.0 %). Erosive esophagitis was diagnosed in 4 cases (0.7 %), 3 of which were in older schoolchildren in Tyva. Erosive-ulcerative diseases of the stomach and duodenum were recorded, to a greater extent, in older children, and largely in Tyva. A more frequent combination of GERD and erosive-ulcerative lesions of the gastroduodenal zone was noted in Tyva, particularly in the older age group.Conclusion. In Siberian schoolchildren, an association of erosive and ulcerative lesions of the mucosa of the gastroduodenal zone with GERD was established, the severity of which has age-related features and is closely related to the region of residence.
Aim. To study age-related features of the association of gastroesophageal reflux disease (GERD) with the activity of the inflammatory process in the gastric mucosa (GM) in schoolchildren. Materials and methods. At the first stage in the Republic of Tuva, we collected data on the presence of gastroenterological complaints in 1535 schoolchildren using a transverse method. At the second stage we performed esophagogastroduodenoscopy with biopsy of the mucous membrane of the antrum and the body of the stomach in two hundred forty six children including 76 cases aged from 7-11 years and 170 patients aged from 12 to 17 years. Morphological assessment of gastritis was carried out according to the Sydney classification after staining biopsy sections with hematoxylin-eosin; diagnostics of Helicobacter pylori - after staining by Giemsa method. The study was approved by the ethical committee and the consent of the surveyed patients was obtained. Results. An increase in the prevalence of GERD was found in the older age group of schoolchildren - 15.6% (7-11 years old - 4.7%; p = 0.0001). GERD schoolchildren showed an insignificant tendency with age to an increase in the activity of the inflammatory process in the mucous membrane of the antrum (p = 0.3408) and the body (p = 0.3346) of the stomach. Among infected GERD schoolchildren in both age groups, gastritis with a high degree (II-III degree) of activity was more often detected than in infected schoolchildren without clinical manifestations of GERD (7-11 years old - p = 0.2551; 12-17 years old - p = 0.0536, respectively) and more often than in those uninfected GERD cases (7-11 years old - p = 0.0082; 12-17 years old - p = 0.0002). The association of highly active forms of gastritis in the body of the stomach in infected schoolchildren with manifestations of GERD has not been established. Conclusion. The presence of GERD in schoolchildren, regardless of age, aggravates the course of the inflammatory process in the antrum. When infected with Helicobacter pylori, GERD and infection in schoolchildren act as factors that mutually aggravate the inflammatory process in the antrum.
Introduction. Functional gastrointestinal disorders (FGID) in infants are a complex of symptoms from the gastrointestinal tract that cannot be explained by structural or biochemical disorders. To alleviate the symptoms of functional disorders, a set of measures is required, first of all, psychological support for the mother and, of course, rational feeding, which includes maintaining breastfeeding, optimizing the nutrition of the nursing mother. Despite the abundance of professional information on this issue, previous studies demonstrate a low level of women’s awareness of nutrition during breastfeeding. The aim of the work is to determine the effectiveness of recommendations on nursing mother’s nutrition in the complex treatment of breastfed children with FGID and allergy to cow’s milk proteins. Materials and methods. Seventy five mother–child pairs were included in the study. 1–4 months infants exclusively breastfed during the study were divided into two groups: 1 — FGID infants (n = 51) and 2 — infants with suspected cow’s milk allergy (CMA) n = 24. In addition to the comprehensive treatment of the child, mothers of both groups were given recommendations on the nursing woman’s nutrition. Mothers of children from group 2 were assigned a diagnostic dairy-free diet for a period of 1 month. Results. On the 2nd visit, when analyzing the symptoms of the FGID in group 1, the number of children with symptoms of regurgitation of more than 2 episodes per day decreased by 28% (p < 0.001), crying for more than 3 hours per day — by 52% (p < 0.001). Children of group 2 with a clear positive effect from the diagnostic dairy-free diet therapy of the mother (n = 20) were diagnosed with Allergic and alimentary gastroenteritis and colitis (K52.2 — 10th revision of ICD-10), the continuation of the dairy-free diet for the mother and the supervision of an allergist were prescribed. The survey of women showed that all nursing women were interested in nutrition issues during lactation, 92% of the surveyed mothers searched for this information on the Internet. At the same time, only 12% of women considered this information to be sufficient. Evaluating the presented materials on nutrition, the overwhelming majority of respondents replied that they helped them to adjust their diet and expand nutrition, as well as to maintain breastfeeding. Conclusion. Thus, an integrated approach in the management of FGID infants and gastrointestinal manifestations of food allergies, including the use of nutrition recommendations developed in the National Medical Research Center of Children’s Health for nursing women, allows achieving a positive effect on the side of symptoms both in FGID and CMA patients, and also contributes to the improvement of the psycho-emotional state of a woman and prolonged breastfeeding.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
customersupport@researchsolutions.com
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.