Current Smoking and Prognosis After Acute ST-Segment Elevation Myocardial Infarction

Abstract

Smoking is associated with enhanced inflammation acutely, infarct-zone hemorrhage subsequently, and longer term adverse cardiac outcomes. Inflammation and irreversible myocardial hemorrhage post-MI represent mechanistic drivers for adverse long-term prognosis in smokers. (Detection and Significance of Heart Injury in ST Elevation Myocardial Infarction. [BHF MR-MI]; NCT02072850).

Impact of Smoking Status on Hospital Outcome of Patients with ST-Segment Elevation Myocardial Infarction Either Treated by Pharmacy-invasive Strategy or Primary Percutaneous Coronary Intervention .

“…Regarding dyslipidemia, our data was matching with what Haig C et al (14) found and we found that there was a statistically significant difference between smokers and non-smokers.…”

Clinical, Angiographic Characteristics and In-Hospital Outcomes of Smoker and Nonsmoker Patients After Primary Percutaneous Coronary Intervention

“…Clinical presentation (Canadian Cardiovascular Society anginal classification) for both smokers and nonsmokers was similar in our study, with similar phenomena that have been reported in the past studies [11,16,25]. Similarly, diabetes and hypertension were less prevalent among smokers than nonsmokers, this is a consistent finding among various studies from other parts of the world [11,15,16,18e29].…”

“…We found a similar distribution of culprit arteries in the smoker and nonsmoker groups, which was consistent with some of the past studies [11,22e25]. But Rakowski et al [16] and Goto et al [19] reported [19] 44.5 vs. 60.1 0.001* Symons et al [22] 42.3 vs. 48.8 0.16 Katayama et al [24] 43.1 vs. 41.9 0.779 Haig et al [25] 26.5 vs. 41.4 0.007* Diabetes mellitus Gupta et al [11] 32.2 vs. 61.7 <0.001* Shemirani et al [23] 17.0 vs. 36.2 0.02* Rakowski et al [16] 10.0 vs. 18.6 <0.001* Goto et al [19] 12.5 vs. 19.7 0.001* Symons et al [22] 11.0 vs. 18.4 0.02* Katayama et al [24] 31.0 vs. 37.2 0.141 Haig et al [25] 10.2 vs. 10.9…”

“…Only 1.2% (10) of the smoker group consisted of women, which is a consistent finding: in Gupta et al [11], it is 1.1%; Shemirani et al [23], 4.26%; and Katayama et al [24], 9.1%. However, the proportion of women in the smoker groups reported in some other populations was around 14% to 29% [16,19,22,25].…”

Frequency of coronary risk factors in patients with acute myocardial infarction in the Cardiology Service of the Hospital de Clínicas

“…Con respecto a los otros factores de riesgo coronarios descritos, llama la atención la alta frecuencia de sedentarismo y de consumo de tabaco, similar a la reportada por otros estudios (17,18) realizados en Colombia y Cuba . También en otras regiones del mundo encontraron que frecuencia (12,14,(19)(20)(21)(22) alta de sedentarismo y de consumo de tabaco como factores de riesgo coronario . En relación a (23) la dislipidemia, c-HDL cumple un rol importante como predictor de enfermedad cardiovascular .…”