Current State of Prevention of Mother-to-Child Hiv Transmission in Saint-Petersburg

Гусев, Д. А.; Самарина, А. В.; Ястребова, Е. Б.; Mozaleva, Olga L.

doi:10.22625/2072-6732-2019-11-1-58-64

Cited by 4 publications

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“…ежегодно в стране регистрируют около 15 тысяч родов у виЧ-инфицированных женщин [6]. в санкт-Петербурге в течение нескольких последних лет число родов у виЧ-инфицированных матерей остается стабильно высоким и составляет 500-700 в год [7,8]. несмотря на большое количество родов в городе, передача виЧ от матери ребенку в санкт-Петербурге происходит реже, чем в среднем по рФ [7,9].…”

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“…в санкт-Петербурге в течение нескольких последних лет число родов у виЧ-инфицированных матерей остается стабильно высоким и составляет 500-700 в год [7,8]. несмотря на большое количество родов в городе, передача виЧ от матери ребенку в санкт-Петербурге происходит реже, чем в среднем по рФ [7,9]. Этому спо собствовала организация взаимодействия между лечебно-профилактическими учреждениями города, оказывающими помощь беремен-ным, включая виЧ-инфицированных женщин.…”

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Analysis of the timing and delivery methods, clinical and laboratory indicators of hiv-infected pregnant women in Saint Petersburg

et al. 2020

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Assessing the timing and delivery methods, clinical and laboratory indicators of HIV-infected pregnant women is important for organizing effective care for this group of patients and further reducing the frequency of perinatal transmission of HIV infection. In 20142017, in Saint Petersburg, there were 2,524 childbirths in HIV-infected women, who were observed during pregnancy mainly in the Center for the Prevention and Control of AIDS and Infectious Diseases (AIDS Center). The average frequency of perinatal HIV transmission in the city over the study period was 1.3%, which is lower than the average for Russia (2.5%). A retrospective and prospective analysis of 1,858 medical records of HIV-infected women observed during pregnancy at the AIDS Center in 20142017 was performed. An annual decrease in the proportion of chronic viral hepatitis C coinfection was found, which was proportional to a decrease in parenteral HIV transmission in the study group. Due to the increase in HIV testing coverage, the frequency of detection of infections in pregnant women in antenatal clinics during registration was reduced. This allows conducting a thorough examination, counseling and a timely initiation of antiretroviral therapy (ART) during pregnancy planning. The vast majority of HIV-infected women are committed to follow-up in medical facilities during pregnancy, to receive antiretroviral prophylaxis (ARP) and, as a result, to give birth to a healthy child. The rate of preterm birth among HIV-infected women is higher than in HIV-seronegative women. This determines the timely initiation of ARP/ART during pregnancy for prevention of preterm delivery. The proportion of births through the birth canal increases annually, but the operative delivery rate remains above the population.

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Analysis of the timing and delivery methods, clinical and laboratory indicators of hiv-infected pregnant women in Saint Petersburg

et al. 2020

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Demographic and Epidemiological Characteristics of the Hiv-Infected Pregnant Women in Saint-Petersburg

Mozaleva

Самарина

2019

VIČ-infekc. immunosupr.

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Analysis of the epidemiological and demographic characteristics of HIV-infected pregnant women is important for organizing effective care for this group of patients and further reducing the frequency of mother-to-child transmission. Between 2014 and 2017 in Saint-Petersburg, there were 2524 deliveries in HIV-infected women who were observed during pregnancy, mainly in the Saint-Petersburg AIDS Center (AIDS Center). The average frequency of perinatal HIV transmission over the study period in the city was 1,3%, which is lower than the average for Russia. Out of 2524 women recently confined, 1858 HIV-infected women, who were observed during pregnancy at the AIDS Center in 2014–2017, were enrolled. Risk groups for perinatal HIV transmission in Saint-Petersburg are HIV-infected pregnant women: external or internal migrants, women with late registration at the dispensary registration for pregnancy in the antenatal clinic and the AIDS Center and, accordingly, late initiation of perinatal HIV transmission, active consumers of surfactants, pregnant women with low adherence to observation in medical institutions and to getting antiretroviral agents. The increase in coverage of the city’s population with HIV testing reveals new infections, including among women of reproductive age, as well as their partners. The timely use of ARV at the planning stage of pregnancy reduces perinatal HIV transmission and the risks of opportunistic diseases. The availability of medical care and free distribution of ARV drugs to all pregnant women who applied to the AIDS Center helps to reduce perinatal HIV transmission, including among internal and external migrants who do not have a permanent registration in Saint-Petersburg. Counseling women at the planning stage and during pregnancy by various specialists of the AIDS Center (gynecologists, infectious disease specialists, psychologists, narcologists) allows one to form a commitment to monitoring, to receiving ARV, giving up bad habits, to reduce the incidence of HIV-dissidence.

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Аnalysis of the epidemiological situation and perinatal HIV infection in the Vologda region

Казачек

Melnikova

Самарина

et al. 2020

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Purpose. To analyze the epidemiological situation and perinatal HIV infection in the Vologda region.Materials and methods. The article provides a retrospective and prospective analysis of data obtained from the forms of state statistical observation and accounting forms of medical documentation, using the Chi-square calculator, Fisher criterion, risk ratio to assess the effectiveness of measures to prevent perinatal HIV transmission in the Vologda region.The results of the study showed that the detection of HIV infection during pregnancy in the Vologda region tends to increase. At the same time, there are still problems such as adherence to dispensary monitoring and treatment in women who have drug dependence, which requires further improvement of the legal framework and clear implementation of approved algorithms by medical professionals.

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Current State of Prevention of Mother-to-Child Hiv Transmission in Saint-Petersburg

Cited by 4 publications

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Analysis of the timing and delivery methods, clinical and laboratory indicators of hiv-infected pregnant women in Saint Petersburg

Analysis of the timing and delivery methods, clinical and laboratory indicators of hiv-infected pregnant women in Saint Petersburg

Demographic and Epidemiological Characteristics of the Hiv-Infected Pregnant Women in Saint-Petersburg

Аnalysis of the epidemiological situation and perinatal HIV infection in the Vologda region

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