Current Status of Cancer Burden: Global and Indian Scenario

Saranath, Dhananjaya; Khanna, Aparna

doi:10.4103/2349-3666.240996

Cited by 71 publications

(45 citation statements)

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“…According to Ferlay et al, 2010, out of 84 countries with prevalence record of cases, India alone is responsible for 7.8% of the global cancer cases and 8.33% of cancer based deaths. Breast, cervix, lung and colorectal cancer are most common types of cancer in India (Saranath and Khanna, 2014). There are about 250,000 registered traditional medicinal practitioners in India.…”

Section: Cancer Status In Different Countriesmentioning

confidence: 99%

A systematic review on ethnomedicines of anti-cancer plants

et al. 2017

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Cancer is a serious health problem and the second leading cause of death around the globe. Present review is an attempt to provide utmost information based on ethno-pharmacological and toxicological aspects of anti-cancer plants of the world. A total of 276 articles published in English journals and containing maximum ethnomedicinal information were reviewed using several data sources such as; Google scholar, Web of Science, Scopus, PubMed and floras of different countries. A total of 199 anti-cancer plants were recorded in present review and results indicated that traditional medicines are mostly being use in developing countries for cancer treatment. Traditionally and scientifically skin and breast cancer types gained more focus. Seventy plants were reportedly analyzed for in-vitro activities while 32 plants were having in-vivo reports. Twenty nine pure compounds (mostly phenolic) were reportedly isolated from anti-cancer plants and tested against different cancer cell lines. Inspite having better efficiency of ethnomedicines as compared to synthetic drugs, several plants have also shown toxic effects on living system. Therefore, we invite researchers attention to carry out detailed ethno-pharmacological and toxicological studies on un-explored anti-cancer plants in order to provide reliable knowledge to the patients and develop novel anti-cancer drugs.

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Section: Cancer Status In Different Countriesmentioning

confidence: 99%

A systematic review on ethnomedicines of anti-cancer plants

et al. 2017

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“…The 5-year survival rate is 75% for local lesions but only 17% for those with distant metastasis. 2 Therefore early diagnosis is the key. Owing to the ease of access for examination and early pre-cancerous lesion or condition as a precursor, it is preventable to a great extent.…”

Section: Discussionmentioning

confidence: 99%

“…Additionally, a high risk of oral cancer in the Indian subcontinent is related to the popularity of betel leaf, lime, areca nut, and sun-cured tobacco chewing. 2,3 Screening for oral cancer is, therefore, a need of an hour in general population, aimed at early detection of precancerous lesions and conditions, invasive cancers with improved survival after treatment of initial stages of cancers. 4 Today, the mobile revolution is offering an excellent way to provide healthcare support when and where people need it.…”

Section: Introductionmentioning

confidence: 99%

A Novel Mobile App for Oral Cancer Awareness amongst General Population: Development, Implementation, and Evaluation

Deshpande¹,

Radke²,

Karemore³

et al. 2019

The Journal of Contemporary Dental Practice

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“…Estimates show that there will be 1.73 million new cases of cancer in India by 2020 and that oral cancer will account for approximately 30% of all cancers. Each year India accounts for 7.8% of global cancer deaths . Furthermore, approximately 80 000 cases are diagnosed annually, with a mean age of occurrence of 55 years in the adult population.…”

Section: Introductionmentioning

confidence: 99%

Oral mucositis and microbial colonization in oral cancer patients undergoing radiotherapy and chemotherapy: A prospective analysis in a tertiary care dental hospital

Subramaniam

Muthukrishnan

2019

J of Invest & Clin Dent

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Aim The ulcerative phase of oral mucositis following radiotherapy/chemotherapy for oral cancer colonizes bacteria, fungi and viruses. The role of a microbiota, specifically bacterial colonization in oral mucositis, is still unclear, and there is no existing data that correlates the shift in the bacterial colonization with mucositis severity. The aim of this study was to assess the bacterial colonization and study the MCR‐1 (mobilized colistin resistance), VIM2 (β‐lactam resistance), TET(K) (tetracycline resistance) and blaKPC (carbapenem resistance) genes’ expression in isolated facultative anaerobes at 3 time points in oral mucositis patients undergoing radiotherapy and concomitant radiochemotherapy. Methods A total of 24 oral cancer patients were divided into 2 groups: A (N = 12) undergoing radiotherapy; and B (N = 12) undergoing radiochemotherapy. Saliva was collected from all patients at 3 time intervals during the treatment. The isolated bacterial colonies were subjected to gene expression and analysis. Results Staphylococcus aureus (22%), Staphylococcus epidermidis (29%), Pseudomonas aeruginosa (28%), Escherichia coli (25%) and Klebsiella pneumoniae (26%) are the facultative anaerobes isolated from saliva. The bacterial isolates obtained during and at the end of therapy appeared to express a higher level of antibiotic‐resistance genes (VIM2, MCR‐1, TET[K], blaKPC) than those isolated at the onset of therapy. Conclusion Bacterial colonization and gene expression varied during different stages of mucositis.

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Current Status of Cancer Burden: Global and Indian Scenario

Cited by 71 publications

References 0 publications

A systematic review on ethnomedicines of anti-cancer plants

A systematic review on ethnomedicines of anti-cancer plants

A Novel Mobile App for Oral Cancer Awareness amongst General Population: Development, Implementation, and Evaluation

Oral mucositis and microbial colonization in oral cancer patients undergoing radiotherapy and chemotherapy: A prospective analysis in a tertiary care dental hospital

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