Custom-made computer-aided-design/ computer-assisted-manufacturing (CAD/CAM) synthetic bone grafts for alveolar ridge augmentation: A retrospective clinical study with 3 years of follow-up

Mangano, Carlo; Luongo, Giuseppe; Luongo, Fabrizia; Lerner, Henriette; Margiani, Bidzina; Admakin, Oleg; Mangano, Francesco

doi:10.1016/j.jdent.2022.104323

Cited by 15 publications

(3 citation statements)

References 43 publications

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“…Key advantages of CBR include improved accuracy and predictability of the augmentation result as the stable scaffold facilitates three-dimensional augmentation and helps to maintain the required space, improving the esthetics and function of the final restoration [5,6]. The unique patient-specific fit allows for unmistakable scaffold placement during surgery, facilitating and shortening the procedure, and potentially reducing complication rates [7][8][9].…”

Section: Discussionmentioning

confidence: 99%

Patient-specific beta-tricalcium phosphate scaffold for customized alveolar ridge augmentation: a case report

Schönegg,

Essig,

Al-Haj Husain

et al. 2024

Int J Implant Dent

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Background Beta-tricalcium phosphate (β-TCP) is a biocompatible ceramic material widely used in the field of oral regeneration. Due to its excellent biological and mechanical properties, it is increasingly utilized for alveolar ridge augmentation or guided bone regeneration (GBR). With recent advances in computer-aided design and manufacturing (CAD/CAM), β-TCP can now be used in the form of digitally designed patient-specific scaffolds for customized bone regeneration (CBR) of advanced defects in a two-stage implant therapy concept. In this case report following the CARE case report guidelines, we present a novel application of a patient-specific β-TCP scaffold in pre-implant mandibular alveolar ridge augmentation. Case presentation A 63-year-old female patient with significant horizontal bone loss in the posterior mandible was treated with a custom β-TCP scaffold in the context of a two-stage backward-planned implant therapy. Cone-beam computed tomography nine months after augmentation showed successful integration of the scaffold into the surrounding bone, allowing implant placement. Follow-up until two years after initial surgery showed excellent oral and peri-implant health. Conclusions This case highlights the potential of patient-specific β-TCP scaffolds for alveolar ridge augmentation and their advantage over traditional techniques, including avoidance of xeno-, allo-, and autografts. The results provide encouraging evidence for their use in clinical practice. Patient-specific β-TCP scaffolds may be a promising alternative for clinicians seeking to provide their patients with safe, predictable, and effective alveolar ridge augmentation results in customized bone regeneration procedures.

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Section: Discussionmentioning

confidence: 99%

Patient-specific beta-tricalcium phosphate scaffold for customized alveolar ridge augmentation: a case report

Schönegg,

Essig,

Al-Haj Husain

et al. 2024

Int J Implant Dent

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“…Thus, our results considering the uneventful healing might be different when applying the scaffolds in the mandible where the scaffolds are exposed to a higher mechanical stress due to muscle tension and the torsion of the mandibular bone itself [ 46 ]. This stress might lead to an exposure of the scaffold and, thus, potentially to an infection as it was observed in a study where milled scaffolds made of synthetic hydroxyapatite/beta-tricalcium phosphate were applied [ 47 ]. In order to evaluate the influence of the location on scaffold integration, further studies with different grafting sites are necessary.…”

Section: Discussionmentioning

confidence: 99%

Three-Dimensional Plotted Calcium Phosphate Scaffolds for Bone Defect Augmentation—A New Method for Regeneration

Schulz

Holtzhausen

Nies³

et al. 2023

JPM

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For sinus grafting, different methods and materials are available. One possible shortcoming of particulate bone grafts is either overfilling or augmenting the planned implant area insufficiently. To overcome this risk and to determine the implant position prior augmentation, we present an approach using three-dimensional printed scaffolds. A patient with a remaining anterior dentition and bilateral severely atrophied posterior maxilla was seeking oral rehabilitation. The cone beam computed tomography (CBCT) showed residual bone heights between one and two millimeters. Following the three-dimensional reconstruction of the CBCT data, the positions of the implants were determined in areas 16 and 26. Three-dimensional scaffolds adapted to the topography of the sinus were virtually designed and printed using a calcium phosphate cement paste. Bilateral sinus floor augmentation applying the printed scaffolds with an interconnecting porosity followed. After nine months, a satisfying integration of the scaffolds was obvious. At the re-entry, vital bone with sufficient blood supply was found. One implant could be placed in positions 16 and 26, respectively. After five months, the implants could be uncovered and were provided with a temporary denture. The application of three-dimensionally printed scaffolds from calcium phosphate cement paste seems to be a promising technique to graft the severely atrophied posterior maxilla for the placement of dental implants.

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“…Les méthodes d'usinage sont les premières qui ont été utilisées pour fabriquer des pièces sur mesure. Il s'agit d'utiliser une fraiseuse 5 axes pour préparer la pièce sur mesure à partir d'un bloc de biomatériau macroporeux [9]. Cette technique est efficace mais elle nécessite des équipements coûteux et il peut être difficile de réaliser des pièces de forme complexe ; une autre limite est liée à la perte importante de matière lors de la préparation de ces greffes.…”

Section: Apports De L'impression 3d Pour La Régénération Osseuse Pré-...unclassified

Impression 3D et bioimpression pour la régénération osseuse en chirurgie orale

Catros,

Fénelon,

De Oliveira

et al. 2024

Med Sci (Paris)

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La chirurgie osseuse pré-implantaire en chirurgie orale permet de reconstruire les atrophies des maxillaires en rapport avec des processus traumatiques, infectieux ou tumoraux. Dans ce contexte, le biomatériau idéal reste l’os autogène mais les biomatériaux (d’origine naturelle ou synthétique) permettent de limiter la morbidité liée aux prélèvements osseux et de simplifier ces interventions chirurgicales. Dans cet article, nous illustrons l’apport récent de l’impression 3D dans ce contexte pour traiter des défauts osseux de forme complexe ou pour créer des modèles anatomiques servant à planifier les interventions. Enfin, les perspectives apportées par l’ingénierie tissulaire et la bioimpression (création de modèles in vitro complexes) sont détaillées.

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Custom-made computer-aided-design/ computer-assisted-manufacturing (CAD/CAM) synthetic bone grafts for alveolar ridge augmentation: A retrospective clinical study with 3 years of follow-up

Cited by 15 publications

References 43 publications

Patient-specific beta-tricalcium phosphate scaffold for customized alveolar ridge augmentation: a case report

Patient-specific beta-tricalcium phosphate scaffold for customized alveolar ridge augmentation: a case report

Three-Dimensional Plotted Calcium Phosphate Scaffolds for Bone Defect Augmentation—A New Method for Regeneration

Impression 3D et bioimpression pour la régénération osseuse en chirurgie orale

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