2021
DOI: 10.29026/oea.2021.200017
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Customized anterior segment photoacoustic imaging for ophthalmic burn evaluation <i>in vivo</i>

Abstract: Photoacoustic imaging has many advantages in ophthalmic application including high-resolution, requirement of no exogenous contrast agent, and noninvasive acquisition of both morphologic and functional information. However, due to the limited depth of focus of the imaging method and large curvature of the eye, it remains a challenge to obtain high quality vascular image of entire anterior segment. Here, we proposed a new method to achieve high quality imaging of anterior segment. The new method applied a curva… Show more

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Cited by 7 publications
(2 citation statements)
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“…A custom-built OR-PAM system (reported previously [28,29] ) was upgraded for the DL-based photoacoustic microscopy-based experiments. Figure 1 presents the schematic of the new system (left) and the imaging part for samples (right, a detailed description in 2.3.…”
Section: Experimental Section 21 Experimental Setupmentioning
confidence: 99%
“…A custom-built OR-PAM system (reported previously [28,29] ) was upgraded for the DL-based photoacoustic microscopy-based experiments. Figure 1 presents the schematic of the new system (left) and the imaging part for samples (right, a detailed description in 2.3.…”
Section: Experimental Section 21 Experimental Setupmentioning
confidence: 99%
“…By converting optical energy into acoustic energy, which is 2–3 orders of magnitude less scattered than photons, PA imaging breaks the optical diffusion limit (1 mm in biological tissue) and significantly extends the imaging depth to ranges that are inaccessible by conventional optical imaging. Generally, PA imaging is classified into two major implementations: scanning-based photoacoustic microscopy (PAM) [5] , [6] and reconstruction-based photoacoustic computed tomography (PACT) [7] , [8] . Transducer arrays with multiple elements are typically used for PA signal detection in PACT, which significantly enhances the imaging speed compared with a single-element transducer that requires point-by-point scanning in the case of PAM.…”
Section: Introductionmentioning
confidence: 99%