Cutaneous Crohn's Disease: Treatment with Intralesional Steroids

Alegre, V.; Pujol, C.; Calatayud, A.; Martínez, Ana Mercedes Victoria; Fortea, José M.; Aliaga, Adolfo

doi:10.1111/j.1365-4362.1989.tb04617.x

Cited by 9 publications

(2 citation statements)

References 12 publications

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“…Studies evaluating the treatment of these skin lesions are still ongoing. Systemic and topical corticosteroids, sulfasalazine, azathioprine and metronidazole have been used successfully in some cases [1,2,7]. When the cutaneous lesions are too large for surgical excision, medical treatment is the only therapeutic alternative.…”

Section: Discussionmentioning

confidence: 99%

Metastatic Crohn's disease

Çizmeci

Önel

Emekli

et al. 2002

European Journal of Plastic Surgery

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Inflammatory bowel disease, especially Crohn's disease, demonstrates many extraintestinal manifestations. As a result, various dermatological lesions that have a different etiopathogenesis can be seen. In the case of metastatic Crohn's disease, extraintestinal granulomatous lesions may be observed in the orofacial and perianal regions, either accompanying bowel symptoms or as the first sign of disease. We report on a 30-year-old woman with sacral metastatic Crohn's disease who was initially treated with topical corticosteroid therapy and then underwent excision of the lesion followed by reconstruction utilizing bilateral advancement flaps.

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Section: Discussionmentioning

confidence: 99%

Metastatic Crohn's disease

Çizmeci

Önel

Emekli

et al. 2002

European Journal of Plastic Surgery

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“…Owing to its rarity, CCD literature on treatment is mostly anecdotal; however, a review article in the Journal of the American Academy of Dermatology has proposed a treatment algorithm for CCD. For single lesions, recommended first-line therapy can be topical super-potent corticosteroids or intralesional corticosteroids, with the addition of oral metronidazole as second-line therapy and systemic corticosteroids as third-line therapy [1,15,16]. In corticosteroid-sensitive areas, topical calcineurin inhibitors are recommended, with systemic corticosteroids as second-line therapy [1,17,18].…”

Section: Dermatology Online Journal || Case Presentationmentioning

confidence: 99%

Cutaneous Crohn disease without gastrointestinal involvement in a 9-year-old boy

Wang

Melnick²,

Penn³

et al. 2018

Dermatology Online Journal

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Surgical management of perineal and metastatic cutaneous Crohn's disease

Williams

Scott

Watson

et al. 1993

Journal of British Surgery

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Skin lesions are the commonest extraintestinal manifestation of Crohn's disease. Lesions that develop at sites remote from the gastrointestinal tract and have granulomas on histological examination are termed metastatic cutaneous Crohn's disease. Management is difficult as medical treatment is often ineffective. This report describes the use of surgical debridement of areas of perineal metastatic cutaneous Crohn's disease in five patients, all of whom had failed to improve after a variety of medical treatments. One patient had a poor result with continuing mild perineal discharge and four had a good outcome with complete resolution of symptoms and satisfactory cosmetic results.

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Cutaneous Crohn's Disease: Treatment with Intralesional Steroids

Cited by 9 publications

References 12 publications

Metastatic Crohn's disease

Metastatic Crohn's disease

Cutaneous Crohn disease without gastrointestinal involvement in a 9-year-old boy

Surgical management of perineal and metastatic cutaneous Crohn's disease

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