Cutaneous lycopene and β-carotene levels measured by resonance Raman spectroscopy: High reliability and sensitivity to oral lactolycopene deprivation and supplementation

Blume-Peytavi, Ulrike; Rolland, Anne; Darvin, Maxim E.; Constable, Anne; Pineau, Isabelle; Voit, Christiane; Zappel, Kristina; Schäfer-Hesterberg, Gregor; Meinke, Martina C.; Clavez, Roger L.; Sterry, Wolfram; Lademann, Jürgen

doi:10.1016/j.ejpb.2009.04.017

Cited by 66 publications

(59 citation statements)

References 26 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…[12][13][14][15] In a number of studies, it was shown that the nutrition influences the values, [16][17][18][19][20][21] whereby stress, in form of sun irradiation, illness or the lack of sleep, reduces the values. [20,22,23] However, up to now, no systematic study about the concentration and distribution of the carotenoids in a representative healthy group of the population has been performed.…”

Section: Wwwantioxorgmentioning

confidence: 99%

Influence on the Carotenoid Levels of Skin Arising from Age, Gender, Body Mass Index in Smoking/Non-Smoking Individuals

Meinke

Lauer

Taskoparan

et al. 2011

Free Radicals and Antioxidants

View full text Add to dashboard Cite

Introduction: Intakes of fruit and vegetables rich in carotenoids are associated with a lower risk for a variety of chronic diseases. Therefore, the carotenoid levels in the skin have been measured in various studies to investigate the effects of nutrition and lifestyle. However, statistically clear data regarding the influence of age, gender, body mass index, and smoking behaviour were not documented. Methods: Thus, non-invasive resonance Raman measurements were performed on 151 healthy volunteers in Berlin, Germany. Results: The investigations have shown significantly enhanced total carotenoid values in the skin for women and non-smokers; individuals with a BMI lower than 30 also showed a trend to higher values. In the case of lycopene, significantly enhanced values were found in people younger than 40 and nonsmokers. Conclusion: Influences of gender, and smoking or non-smoking must be taken into account when carrying out a study with respect to the carotenoids. Age does not play any role for total carotenoids but for lycopene.

show abstract

Section: Wwwantioxorgmentioning

confidence: 99%

Influence on the Carotenoid Levels of Skin Arising from Age, Gender, Body Mass Index in Smoking/Non-Smoking Individuals

Meinke

Lauer

Taskoparan

et al. 2011

Free Radicals and Antioxidants

View full text Add to dashboard Cite

show abstract

“…33 Very little is known about the influence of carotenoid supplementation on African skin. First, although various studies have shown an increase in skin carotenoid concentration and skin yellowness due to carotenoid supplementation in Caucasian skin, 20,21,27,28,34 to our knowledge, no study has yet examined the effect of carotenoid supplementation on African skin. Second, we previously found that African observers significantly increased skin yellowness (and lightness) in same race facial images to increase the facial images' apparent health.…”

Section: Introductionmentioning

confidence: 99%

“…19 Supplementation with beta-carotene (and increased dietary intake of fruit and vegetables) also produces an increase in the normal skin yellowness 20-22 -but not skin redness or luminance 21 -of Caucasian skin, and studies have shown that a somewhat yellower skin color is considered healthier and more attractive by both African and Caucasian observers. 20,[23][24][25] Skin carotenoid concentrations are highly correlated with serum carotenoid concentrations [26][27][28] and can, therefore, provide a noninvasive index of systemic carotenoid concentrations. Skin carotenoid concentrations can also serve as biomarkers for fruit and vegetable consumption, [20][21][22]29 the antioxidative capacity of human skin, oxidative stress, in general, 30,31 and possibly vitamin A levels [since beta-carotene is a precursor of vitamin A (Ref.…”

Section: Introductionmentioning

confidence: 99%

Effect of beta-carotene supplementation on African skin

Coetzee

Perrett

2014

J. Biomed. Opt

View full text Add to dashboard Cite

Abstract. The quantification of skin carotenoid levels has a range of applications in Caucasian populations, from serving as a versatile and noninvasive biomarker (e.g., of systemic carotenoid levels, carotenoid consumption, the antioxidative capacity of skin, and oxidative stress) to being used in appearance-based interventions. Yet, no study has investigated the quantitative effect of carotenoid supplementation on African skin. The aim of this study was to determine if beta-carotene supplementation produces a significant color change in three different regions of African skin. To do so we supplemented the diet of African participants with beta-carotene over an eight-week period. Reflectance spectrophotometry measurements were taken on a weekly basis for the duration of the supplementation study. Results show a significant increase in the carotenoid coloration of lightly pigmented skin (palm of the hand) and highly pigmented skin with low sun exposure (inner arm) after supplementation. The latter was no longer significant after Bonferroni correction. The carotenoid coloration of highly pigmented skin areas with high sun exposure did not increase significantly. Skin carotenoid measurements of the palm of the hand might, therefore, serve as a potential biomarker for systemic carotenoid concentrations in people of African descent.

show abstract

“…The strong correlation between carotenoid-rich nutrition and blood plasma carotenoids is observed for healthy volunteers, since carotenoids are not synthesized in the human organism [38][39][40][41]. This effect can be interpreted as a positive effect in the course of recovery and should additionally be studied in the case of dengue patients.…”

mentioning

confidence: 99%

Comment on ‘Dengue viral infection monitoring from diagnostic to recovery using Raman spectroscopy’

2016

View full text Add to dashboard Cite

show abstract

Cutaneous lycopene and β-carotene levels measured by resonance Raman spectroscopy: High reliability and sensitivity to oral lactolycopene deprivation and supplementation

Cited by 66 publications

References 26 publications

Influence on the Carotenoid Levels of Skin Arising from Age, Gender, Body Mass Index in Smoking/Non-Smoking Individuals

Influence on the Carotenoid Levels of Skin Arising from Age, Gender, Body Mass Index in Smoking/Non-Smoking Individuals

Effect of beta-carotene supplementation on African skin

Comment on ‘Dengue viral infection monitoring from diagnostic to recovery using Raman spectroscopy’

Contact Info

Product

Resources

About