Cutaneous Manifestations of Internal Malignancies: An Overview

Pipkin, Clare A.; Lio, Peter A.

doi:10.1016/j.det.2007.08.002

Cited by 89 publications

(96 citation statements)

References 92 publications

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“…[17][18] Skin lesions of Bazex usually precede the diagnosis of primary tumor in 65-70%, follow the diagnosis in 10-15% and have concurrent onset in 15-25% of cases. [19] In our study one (50%) patient developed skin lesions seven months prior to the diagnosis of adenocarcinoma stomach, while another patient (50%) had concurrent onset. The triad of pancreatitis, panniculitis and polyarthritis is known as PPP syndrome.…”

Section: Discussionmentioning

confidence: 93%

Dermatological Manifestations of Gastrointestinal Tract Malignancies: A Rare Prospective Study

Chauhan¹

2017

jmscr

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Section: Discussionmentioning

confidence: 93%

Dermatological Manifestations of Gastrointestinal Tract Malignancies: A Rare Prospective Study

Chauhan¹

2017

jmscr

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“…Zaobserwowano również korzystne działanie somatostatyny, jednak całkowite ustąpienie zmian można uzyskać tylko przez usunięcie nowotworu. Inny możliwy czynnik wywołujący objawy to stwierdzany u tych chorych niedobór niacyny [45].…”

Section: Zespół Glukagonomaunclassified

Dermatologic symptoms associated with gastrointestinal neoplasia

Młynarczyk-Bonikowska¹,

Muszyński²,

Majewski³

2017

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StreSzczenieNowotwory układu pokarmowego należą do najczęściej występujących chorób i są również jedną z najczęstszych nowotworowych przyczyn zgonów na świecie. Obecność charakterystycznych zmian skórnych pozwala na szybsze rozpoznanie i leczenie, a tym samym zwiększenie prawdopodobieństwa wyleczenia. W artykule przedstawiono najważ-niejsze skórne zespoły paraneoplastyczne, które mogą współistnieć z nowotworami przewodu pokarmowego, w tym rakiem jelita grubego, żołądka i przełyku oraz trzustki. Uwzględniono zespoły uwarunkowane genetycznie, takie jak zespół Cowden, zespół rodzinnie występu-jących licznych znamion atypowych -czerniak lub rak trzustki, zespoły Clarke Howela-Evansa, Peutza-Jeghersa, Muira-Torrego, Gardnera, zespoły nabyte, takie jak rogowacenie ciemne złośliwe, zespół tripe palms, Lesera-Trelat, Bazexa, hypertrichosis lanuginosa, erythema gyratum repens, zespół rakowiaka, zespół glukagonoma, a także przerzuty nowotworowe do skóry oraz nowotwory w niektórych przypadkach zapalenia skórno-mięśniowego. AbStrActGastrointestinal tumors are among the most common neoplastic causes of death worldwide. Presence of characteristic skin lesions can allow faster diagnosis and therapy and this way can increase the probability of a cure. In the paper we present the most important paraneoplastic syndromes that can coexist with gastrointestinal malignancy including colon, gastric, esophagus and pancreatic cancers. We take into account genetic syndromes such as Cowden syndrome, familial atypical multiple mole melanoma syndrome (FAMMM) (melanoma/pancreatic cancer), Clarke Howel-Evans, Peutz-Jeghers, Muir-Torre, Gardner syndromes and acquired syndromes such as acantosis nigricans maligna, tripe palms, Leser-Trelat, Bazex, hypertrichosis languinosa, erythema gyratum repens, carcinoid and glucagonoma syndrome. We also include cutaneous metastases and coexistence of neoplasia in some cases of dermatomyositis.

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“…Deride koyulaşma, melanin birikimi ve melanosit çoğalması ile değil hiperkeratozla ilişkilidir. [4,5] OLGU SUNUMU Kırk dört yaşında erkek hasta üç-dört ay içinde gelişen deride koyulaşma ve kalınlaşma, yaygın vücut ağrısı ve kilo kaybı ile kliniğimize başvur-du. Fizik muayenesinde özellikle boyun, aksilla, inguinal bölge, el ve ayakta akantosis nigrikans ile uyumlu cilt lezyonları mevcuttu (Şekil 1).…”

Section: Dicle üNiversitesi Tıp Fakültesi Tıbbi Onkoloji Bilim Dalıunclassified

The case of gastric adenocarcinoma applying with malign Acanthosis Nigricans

Oruç¹

2015

TJ Oncol

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Achantosis Nigricans (AN) is a skin disorder characterised with hyperpigmented hyperkeratotic lesions. It occurs mostly in association with insulin resistance while it may also arise as a symptom of visceral malignancies. In the occurrence of AN considered as associated with malignancy, a detailed examination may be necessary to identify underlying malignancy. 85% of malign AN cases abdominal adenocarcinomas, and especially 60% of those are gastric adenocarcinomas. A 44-year-old male patient applied to our clinic with hyperpigmentation and hyperkeratosis, widespread body pain and weight loss within 3-4 months. Skin symptoms were reviewed as acanthosis nigricans. He had no endocrinological diseases such as DM or obesity. Due to ocurrence of many skin symptoms in accordance with acanthosis nigricans in a rapid growth on our patient, no findings of other AN causes, systemic symptoms such as the age of patient and weight loss, it is considered as malign AN.Keywords: Acanthosis nigricans.Akantozis Nigrikans (AN), hiperpigmente hiperkeratotik lezyonlarla karakterize bir cilt hastalığıdır. Çoğu insülin resistansı ile ilişkili olmakla birlikte nadiren viseral malignitelerin bir bulgusu olarak da ortaya çıkabilir. Malignite ile ilişkili olduğu düşünülen AN varlığında altta yatan malignensinin saptanması için ayrıntılı inceleme yapılması gerekebilir. Abdominal adenokarsinomalar malign AN olgularının %85'ini özellikle gastrik adenokarsinomalar %60'ını oluşturmaktadır. Kırk dört yaşında erkek hasta üç-dört ay içinde gelişen deride koyulaşma ve kalınlaşma, yaygın vücut ağrısı ve kilo kaybı ile kliniğimize başvurdu. Cilt bulguları AN olarak değerlen-dirildi. Diabetes mellitus, obezite gibi endokrinolojik hastalıklar yoktu. Hastamızda akantozis nigrikans ile uyumlu cilt bulgularının yaygın olması ve hızlı gelişmesi, diğer AN nedenlerinin bulunmaması, hastanın yaşı ve hastada kilo kaybı, yaygın vücut ağrısı gibi sistemik bulgularının da bulunması nedeniyle malign AN olarak değerlendirildi.

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Cutaneous Manifestations of Internal Malignancies: An Overview

Cited by 89 publications

References 92 publications

Dermatological Manifestations of Gastrointestinal Tract Malignancies: A Rare Prospective Study

Dermatological Manifestations of Gastrointestinal Tract Malignancies: A Rare Prospective Study

Dermatologic symptoms associated with gastrointestinal neoplasia

The case of gastric adenocarcinoma applying with malign Acanthosis Nigricans

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