Cutaneous Meningioma

Miedema, Jayson; Zedek, Daniel C.

doi:10.5858/arpa.2010-0505-rs

Cited by 38 publications

(66 citation statements)

References 28 publications

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“…Therefore, they should be included in the differential diagnosis when evaluating FNA material from tumors in this anatomical site. Cutaneous meningioma most commonly occurs on the scalp and may be congenital (ectopic) or acquired (representing a secondary extension from an underlying intracranial meningioma) [29]. Our patient (case 4) with multiple scalp lesions had a prior brain meningioma.…”

Section: Discussionmentioning

confidence: 93%

Cytopathology of Extracranial Ectopic and Metastatic Meningiomas

et al. 2013

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Introduction: Extracranial meningiomas may infrequently be encountered as ectopic or metastatic tumors. Their rarity and unique cytomorphology often pose significant diagnostic dilemmas. The aim of this study was to report our experience with a series of ectopic and metastatic meningiomas, characterizing their cytomorphology with histological correlation. Materials and Methods: A retrospective analysis involving 13 patients with cytological preparations from extracranial meningiomas was performed. Cytology cases were correlated with available surgical resection specimens. Data regarding clinical findings, tumor information, cytomorphology, follow-up histological features and immunohistochemistry were recorded and analyzed. Results: There were 5 cases with metastases and 8 ectopic meningiomas. Metastases occurred in the scalp/skull, lung, paraspinal soft tissue and liver. Primary ectopic meningiomas were located in the paranasal sinuses and ear, orbit and neck. Cytomorphological features characteristic of meningiomas were identified in the majority of samples including tightly cohesive clusters of spindled cells, whorls, intranuclear inclusions, nuclear grooves and psammomatous calcification. Unusual cytomorphological features identified in only a few cases included epithelioid cell predominance, abundant inflammatory cells, small-cell change, papillary structures and pseudoacinar growth. Metastatic tumors exhibited more nuclear atypia and occasionally mitoses or necrosis. Meningiomas were shown to be immunoreactive for epithelial membrane antigen, pancytokeratin and vimentin. Conclusion: Although rare, extracranial meningiomas can be encountered in cytologic specimens and should be included in the differential diagnosis when characteristic morphological features of meningiomas are seen. Cytopathologists should be aware that these lesions could be mistaken for other tumors, especially when confounded by atypia and unusual cytomorphological features.

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Section: Discussionmentioning

confidence: 93%

Cytopathology of Extracranial Ectopic and Metastatic Meningiomas

et al. 2013

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“…Because meningiomas are rare tumors associated with vague clinical features, they may have to be differentiated from lesions such as appendageal cell tumors, epithelioid/spindle cell sarcoma, peripheral nerve sheath tumors, squamous cell carcinoma, hemangioma, giant cell fibroblastoma, hemagiopericytoma, or other types of heterotopic neuroglial lesions. [2345] FNAC is a simple and effective procedure and can be highly valuable in diagnosis of cutaneous meningioma, as done in the present case.…”

Section: Discussionmentioning

confidence: 61%

“…However, if the lesion is small and asymptomatic, simple surgical excision can be considered. [25] In our case, the lesion was completely excised and sent for histopathological confirmation. Some studies found that cutaneous meningioma Type I has better prognosis.…”

Section: Discussionmentioning

confidence: 86%

“…These are most commonly found in the scalp and occur in both congenital and acquired forms. [2] They may be (a) an extension through foramina or defect, (b) may arise from embryonic arachnoid cells/multipotent mesenchymal cells anywhere in the body, and (c) may represent metastasis from primary intracranial/supraspinal meningioma. Extracranial and extraspinal meningiomas are rare and should be included as a differential diagnosis while examining FNAC from tumor, especially from the head and neck regions.…”

Section: Discussionmentioning

confidence: 99%

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Cutaneous meningioma: A cytomorphological diagnosis

Kishore¹,

Bhardwaj²,

Sharma³

2017

Indian Dermatol Online J

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Cutaneous meningiomas are rare tumors. These are ectopic meningothelial cells located in the dermis and subcutis, and are usually seen on the scalp. Here, we report the case of a 40-year-old woman who presented with a slowly growing asymptomatic mass over the scalp in the right parieto-occipital region. The lesion was firm, adherent to underlying structures, and covered by normal appearing skin. The cytomorphological features along with histological and immunohistochemical studies showing positivity for epithelial membrane antigen, Vimentin, and S100 helped in making a definitive diagnosis of cutaneous meningioma. No evidence of intracranial meningioma was noted in contrast-enhanced computed tomography of the brain.

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“…They are generally considered benign, particularly if classified as WHO grade I 1. Despite the first reported case in the English literature being in 1956, cutaneous meningioma remains a relatively rare tumour 2. Lopez et al 3 classify cutaneous meningiomas into three types: primary cutaneous meningiomas (type I), which are generally congenital; cutaneous extensions of extracranial soft tissue meningiomas (type II); and cutaneous meningiomas arising from an extension of a neuraxis meningioma to the skin (type III).…”

Section: Introductionmentioning

confidence: 99%

Recurrent meningioma of the scalp after 13 years

Ashmore¹,

Clancy

Chumas

2016

BMJ Case Reports

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Meningiomas represent some of the most common types of tumour of the central nervous system. They are considered benign, with ∼1 in 1000 known to metastasise. We report a case of recurrent meningioma of the scalp 13 years following craniotomy to treat the primary. The recurrent tumour of the scalp was eventually excised 5 years later and the defect closed with an anterolateral thigh free flap in a joint procedure between the neurosurgeons and plastic surgeons. Histology of the scalp lesion confirmed a WHO grade I meningioma. Although a number of explanations for recurrent scalp meningiomas exist, the precise role of isolated genetic defects in scalp meningiomas is incomplete. The scalp meningioma in this case consisted of a complex karyotype suggestive of more aggressive disease. This case emphasises that cytogenetics may play a greater role in identifying more aggressive tumours than histology alone.

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Cutaneous Meningioma

Cited by 38 publications

References 28 publications

Cytopathology of Extracranial Ectopic and Metastatic Meningiomas

Cytopathology of Extracranial Ectopic and Metastatic Meningiomas

Cutaneous meningioma: A cytomorphological diagnosis

Recurrent meningioma of the scalp after 13 years

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