Cutaneous progressive angiomatosis on the muzzle of a dog, treated by laser photocoagulation therapy

Abstract

A 10-year old, female, cocker spaniel was presented with a bleeding lesion on the muzzle and nasal planum observed initially as a small raised nodule at 1 year of age. This became clinically more pronounced at 5 years of age, progressively enlarged thereafter and was diagnosed initially as a vascular tumour. On clinical examination, multiple confluent nodules of variable diameter (0.5-1.5 cm) deformed the outline of the nose. Histological examination revealed a progressive angiomatosis with multifocal infiltrative growth of increased dermal vascularization with different sized and type of anastomosing vessels lined by a monolayer of reactive endothelium, often arranged as papillary projections into the lumina. Partial nosectomy, the first therapeutic approach, was unsuccessful and the lesion relapsed within 6 months. However, subsequent laser photocoagulation therapy provided a good cosmetic outcome, no relapse 1 year later, and appeared to provide an effective alternative to ablation surgery.

Multi‐system progressive angiomatosis in a dog resembling blue rubber bleb nevus syndrome in humans

“…, Olivieri et al . ). Generalised or multi‐centric forms of progressive or non‐progressive angiomatosis limited to cutaneous and subcutaneous lesions have been recognised in few dogs, and the lesions of these cases were reported to be less aggressive (Gross et al .…”

“…, Olivieri et al . ), progressive angiomatosis, scrotal vascular hamartoma (Gross et al . ) and skeletal‐extraskeletal angiomatosis (Kuroki et al .…”

Feline vertebral angiomatosis: two cases

“…Vertebral angiomatosis is a rare vascular malformation with few cases reported in the literature. 1 – 5 In dogs several forms of angiomatosis have been reported including cutaneous, 6 , 7 cardiac, 8 meningeal, 9 skeletal 10 and multisystemic forms, 11 whereas in cats it is a little-known disorder. 12 In terms of spinal cord disease in cats or, in general, neurological disorders in feline species, this disease has not previously been considered.…”

Retroperitoneal lymphatic malformation in a dog

“…However, vascular malformations have been reported to have a progressive behaviour and a tendency to expand into surrounding tissues [2,25,26]. Progressive angiomatosis is well known for its invasive behaviour, which is also described in previous cases of canine vascular-and lymphatic malformations [8,9,25]. Thus, differentiation between a tumor and a vascular malformation can be challenging.…”

“…A review of the veterinary literature suggests that the vast majority of vascular malformations are of blood vessel origin [5][6][7][8][9][10][11][12][13][14][15]. Only few reports confirm a lymphatic vessel origin of vascular malformations in the skin, intestines, liver and mammary gland [16][17][18][19][20][21].…”