Cutaneous Rhodotorula Treated with Photodynamic Therapy

Means, Alexander D.; Sisto, Krisanne; Lichon, Vanessa; Monaghan, Diana; O’Keefe, Paul; Tung, Rebecca

doi:10.1111/j.1524-4725.2012.02373.x

Cited by 7 publications

(8 citation statements)

References 7 publications

(23 reference statements)

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“…Two nonsense mutations also located in last exon of the EDAR gene, the recurrent p.Arg358X and p.Glu354X, have been reported to result in mild autosomal dominant HED through a similar mechanism. 9,10 In conclusion, we have identified a novel frameshift mutation in an Italian family with autosomal dominant HED resulting in…”

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confidence: 73%

Rhodotorula mucilaginosa skin infection in a patient treated with sorafenib

Coppola

Zanframundo

Rinati

et al. 2014

Acad Dermatol Venereol

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of the species is R. mucilaginosa; it is a ubiquitous pathogen isolated from many sources such as shower curtains, bathtubs, tooth brushes and medical equipments. Before 1985, Rhodotorula was not considered yet as a pathogen, but today it is known to cause significant infections in immunocompromised patients, usually with a malignancy or immunosuppression. Fungemia associated with central venous catheter is the most common consequence of R. mucilaginosa, followed by eye infection (keratitis and endophthalmitis), meningitis, opportunistic onycomycosis and peritonitis. 7,8 Skin infections are extremely rare. Means et al. reported a case of cutaneous R. mucilaginosa treated with photodynamic therapy. 9 Jaeger et al. described a case of R. mucilaginosa folliculitis in Li-Fraumeni-like syndrome. 10 Amphotericin B is considered the gold standard therapy for this infection.Due to the patient's HCC history and chemotherapy with sorafenib, the patient had a higher risk to develop opportunistic infections. We describe the first case of R. mucilaginosa skin infection in a patient with HCC treated with sorafenib.

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mentioning

confidence: 73%

Rhodotorula mucilaginosa skin infection in a patient treated with sorafenib

Coppola

Zanframundo

Rinati

et al. 2014

Acad Dermatol Venereol

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“…5 Other cases of cutaneous Rhodotorula infection have been reported. 2,3 Our patient is unusual as his infection presented over 30 years post-transplant. It is likely that Rhodotorula was acquired when he recommenced haemodialysis, possibly due to his elbow injury or his central venous catheters.…”

Section: Reportmentioning

confidence: 87%

“…Steroids predispose to yeast fungaemia because of their effects on cellular immunity . Other cases of cutaneous Rhodotorula infection have been reported …”

Section: Reportmentioning

confidence: 99%

“…Rhodotorula is a basidiomycetous yeast similar to Cryptococcus. 3 It has been isolated from numerous environmental sources, everyday items and medical devices, including dialysis equipment. 4 It can colonize humans, including the skin, gastrointestinal and respiratory tracts.…”

Section: Reportmentioning

confidence: 99%

“…4 It can colonize humans, including the skin, gastrointestinal and respiratory tracts. 3 Rhodotorula was originally not considered pathogenic, but since the mid-1980s, infections have been increasingly recognized, 1 possibly because of increasing use of central venous catheters 4 or previous diagnostic difficulties. Rhodotorula infections most frequently present as fungaemia, related to central venous catheters, but ocular infection, meningitis, onychomycosis and peritonitis also occur.…”

Section: Reportmentioning

confidence: 99%

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A case of cutaneousRhodotorulainfection mimicking cryptococcosis

et al. 2016

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Rhodotorula is a ubiquitous environmental and commensal yeast, and an emerging opportunistic pathogen, particularly in immunocompromised individuals. Clinical infections with Rhodotorula have been increasingly recognized over the past 30 years; however, infections in solid-organ transplant recipients are uncommon, and cutaneous manifestations have rarely been reported. We describe a 59-year-old male renal transplant recipient, who developed cutaneous infection with Rhodotorula upon failure of his graft and commencement of haemodialysis.

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