Cutis marmorata telangiectatica congenita with skin ulcerations in a new born

Abstract

Cutis marmorata telangiectatica congenita (CMTC) is a rare congenital disorder with persistent cutis marmorata, telengiectasia, and phlebectesia, which may be associated with cutaneaus atrophy and ulceration of the involved skin. We herewith report a full-term newborn female baby with CMTC at birth with ulceration over the extensor aspects of both the knee joints and right elbow joint. CMTC is a benign vascular anomaly representing dilatation of capillaries and veins of dermis and is apparent at birth. The baby had a reticulated bluish purple skin changes all over the body including the face and limb. Although it resembled physiological cutis marmorata, it was strikingly pronounced and definitely was unvarying and permanent. A variety of vascular malformation has been described along with this disorder. Etiology is not very clear and may be multifactorial, teratogens and genes are also been suggested. Prognoses in uncomplicated cases are good.

Limb length discrepancy in cutis marmorata telangiectatica congenita: an audit of assessment and management in a multidisciplinary setting

“…6 Reticulate vascular mottling can be a normal physiological appearance in the neonatal period, but this is transient in an otherwise healthy baby. The pathogenesis of the condition is unclear and most cases appear sporadically.…”

“…The pathogenesis of the condition is unclear and most cases appear sporadically. 6 Reticulate vascular mottling can be a normal physiological appearance in the neonatal period, but this is transient in an otherwise healthy baby. CMTC should be suspected if the vascular markings persist and especially if there are other congenital abnormalities.…”

Cutis Marmorata Telangiectatica Congenita in a Preterm Female Newborn: Case Report and Review of the Literature

“…2,17 Review of the literature indicates that more than 50% (18.8%-89%) of the CMTC patients present associated cutaneous and/or extracutaneous anomalies. 3,[5][6][7][8]10,[18][19][20][21][22][23][24] This variability may be explained by the lack of precise diagnostic criteria. The first association with congenital anomalies was described by Petrozzi et al in 1970: they found a patent ductus arteriosus and a Sturge-Weber syndrome.…”

“…Clinical features include persistent cutis marmorata, telangiectasia and phlebectasia, generalized or most commonly localized, especially at the lower limbs, followed by the trunk and face. [2][3][4][5][6] Occasionally ulceration and atrophy of the involved skin may be present. 5,7,8 The reticulated mottling frequently becomes more prominent in cold environment but doesn't disappear with warming.…”

“…[2][3][4][5][6] Occasionally ulceration and atrophy of the involved skin may be present. 5,7,8 The reticulated mottling frequently becomes more prominent in cold environment but doesn't disappear with warming. 9 Our baby, as described, showed more pronounced lesions at the left leg but skin ulcerations were not present.…”