Cutis marmorata telangiectatica congenita (CMTC) is a rare congenital disorder with persistent cutis marmorata, telengiectasia, and phlebectesia, which may be associated with cutaneaus atrophy and ulceration of the involved skin. We herewith report a full-term newborn female baby with CMTC at birth with ulceration over the extensor aspects of both the knee joints and right elbow joint. CMTC is a benign vascular anomaly representing dilatation of capillaries and veins of dermis and is apparent at birth. The baby had a reticulated bluish purple skin changes all over the body including the face and limb. Although it resembled physiological cutis marmorata, it was strikingly pronounced and definitely was unvarying and permanent. A variety of vascular malformation has been described along with this disorder. Etiology is not very clear and may be multifactorial, teratogens and genes are also been suggested. Prognoses in uncomplicated cases are good.

Introduction: Typhoid fever is estimated to have caused 26.9 million cases and 5.74 lakhs deaths worldwide in 2010. It remains a major public health problem in India and other part of developing world. Background: Nonprovision of safe drinking water and sanitation measures, non-implementation of adequate vaccination strategies and emergence of multidrug resistant salmonella strains is responsible for why typhoid fever is till now remaining an important health problem in some parts of world and the disease is even becoming more complex. Objective: This study was conducted in a tertiary care centre to find out the clinico-epidemiological profile of patients admitted with typhoid fever. Design: Cross sectional observational study. Subjects: 460 Widal positive typhoid fever pediatric cases admitted from 1 st June 2016 to 30 th November 2016. Methods: Both clinical and laboratory data of all the patients were retrieved, compiled and analyzed. Results: Out of 460 patients 238(51.74%) were males and 222 (48.26%) were females. Fever (100%), vomiting (49.13%), diarrhea (30.21%), cough (30.0%) and hepatomegaly (73.26%) were commonly observed.Response to injection Ceftriaxone was excellent.355(77.17%) patients responded to Ceftriaxone alone and 99 (21.52%) patients needed addition of oral Azithromycin.Average hospital stays in our study ranged from 3-9 days. Conclusion: In the present series typhoid fever accounted for 10.94% of pediatric admissions. Though mortality has significantly reduced typhoid fever continues to be an important cause of hospitalization in pediatric population.High incidence among lower age group indicates high endemicity and emphasizes the need of widespread use of vaccination.

Introduction:Congenital anomalies are a major cause of neonatal mortality and morbidity both in developed and developing countries. It accounts for 8-15% of perinatal deaths and 13-16% of neonatal deaths in India. Aims and Objective: This study was done to determine the proportion and changing pattern of congenital anomalies in live newborns and to study the associated maternal and perinatal risk factors. Materials and Method: This is a hospital based cross-sectional descriptive study and was conducted in Bankura Sammalini Medical College and Hospital, West Bengal India during the period July 2016 to December 2017. Results: During his period 31989 babies were born, of which 598 had congenital malformations, making the prevalence 1.86%. Distribution of malformation was predominant among males than in females (66.7 vs. 32.6%; p < 0.05). Discussion: The predominant system involved was musculo-skeletal system followed by cardiovascular and genitourinary system. Congenital anomalies were more likely associated with low birth weight, prematurity, multiparity, consanguinity and caesarean delivery. Various maternal risk factors were studied as well as the role of early preventive interventionalstrategies. Conclusion: Public awareness is to be created and early prenatal diagnosis and management of common anomalies is highly recommended.