CV3 Real-World Characterization of Hypertension Patients in Japan: A 1-Year Overview

Abstract

OBJECTIVES: To assess the impact of dementia on evidence-based medication use after admission for patients with acute coronary syndrome (ACS) across different age groups. METHODS: Of 87,298 patients hospitalized for ACS between January 1, 2006 and December 31, 2007, 1835 patients with dementia and 3670 matched patients without dementia (1:2 ratio, matched by age, gender, and admitted hospital level) were identified from Taiwan's National Health Insurance Research Database. Use of evidence-based medications post-discharge were compared between patients with and without dementia across different age groups (Յ65, 66-75, 76-85, Ͼ85). Multivariate logistic regression models were performed to examine the impact of dementia on use of evidence-based medications. RESULTS: Overall, dementia was associated with a 22% lower likelihood of use of evidence-based medications (adjusted odds ratio (OR) ϭ 0.78, CIϭ0.68-0.89) in ACS patients. The use of evidence-based medications decreased with age, and dementia worsened the utilization. The proportions of patients receiving evidence-based medications were 85.6% (without dementia) versus 73.6% (with dementia) in the youngest age group and 62.0 % (without dementia) versus 55.6% (with dementia) in the oldest age group. CONCLUSIONS: Dementia and aging were associated with the use of evidence-based medications in ACS patients.

The Blood Pressure and Therapy Expenditure Change Due to Hypertension Comorbidity: An Analytical Prospective Study in Secondary Care Hospitals in Jogjakarta Indonesia

“…The elderly was a risk factor for hypertension, its comorbidity, and higher therapy cost [7]. The subjects in all groups had relatively old age exceeding 60 y due to the study setting is done in the secondary care hospitals that generally served more subjects with comorbidity.…”

“…[18] The DBP in all groups was similar and lower than 90 mmHg. Blood pressure with higher SBP but relatively normal DBP was attributed as isolated systolic hypertension and influenced by the age factor [7,18].…”

“…The cardiovascular disease caused the highest mortality in 2012 including 7.4 million for coronary heart disease and 6.7 million for stroke [3]. Hypertension became health burden in worldwide including the low and middle-income countries [4][5][6][7]. Diabetes, previously known as heart disease equivalent, [8] and hypertension also caused the incidence of chronic kidney disease (CKD) at 44% and 28% [9].…”