Cyclodestructive Procedures

Fankhauser, Franz; Kwasniewska, Sylwia

doi:10.1159/000076839

Cited by 7 publications

(2 citation statements)

References 22 publications

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“…Although both TSCPC and CCT techniques have proven effective, there have been concerns regarding postoperative complications, particularly with the latter. The most commonly reported complications include postoperative pain, anterior chamber reaction, corneal oedema, and hyphema (Dastiridou et al, 2018; Fankhauser & Kwasniewska, 2004; Ndulue et al, 2018). Previous research suggested that CCT resulted in more postoperative pain, vision loss, and devastating sequelae (Benson & Nelson, 1990; Goldenberg‐Cohen et al, 2005; Krupin et al, 1978; Wagle et al, 1998).…”

Section: Discussionmentioning

confidence: 99%

Efficacy and safety of transscleral cyclophotocoagulation versus cyclocryotherapy in the treatment of intractable glaucoma: A systematic review and meta‐analysis

Wang,

Yen,

Kuo

et al. 2023

Acta Ophthalmologica

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To perform a meta‐analysis to compare the efficacy and safety of diode laser transscleral cyclophotocoagulation (TSCPC) and cyclocryotherapy (CCT) in the treatment of intractable glaucoma. Systemic searches of the Ovid MEDLINE, EMBASE, and Cochrane Library databases yielded experimental and observational comparative studies. TSCPC and CCT efficacy and safety outcomes were compared. Subgroup analyses of participant ethnicity, preoperative intraocular pressure (IOP) level, and underlying causes of glaucoma were conducted. The pooled effects were computed using the random‐effects model. The meta‐analysis included nine studies totalling 668 eyes. There was no statistically significant difference between the TSCPC and CCT groups in the IOP reduction (IOPR%), decrease in antiglaucoma medications, the operative success rate with or without medications, or retreatment rate in the efficacy analysis. In the subgroup analysis, CCT had a better IOP‐lowering effect among non‐Asian participants and a non‐inferior IOPR% to TSCPC among Asian participants. TSCPC and CCT were associated with similar rates of deterioration in visual acuity, postoperative visual analog scale, and other analysed postoperative complications in the safety analysis. In both groups, severe complications were uncommon. Diode laser TSCPC and CCT had nearly equivalent clinical efficacy in treating intractable glaucoma, while CCT demonstrated a better IOP‐lowering effect in non‐Asian. Both cyclodestructive procedures have a comparable safety profile.

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Section: Discussionmentioning

confidence: 99%

Efficacy and safety of transscleral cyclophotocoagulation versus cyclocryotherapy in the treatment of intractable glaucoma: A systematic review and meta‐analysis

Wang,

Yen,

Kuo

et al. 2023

Acta Ophthalmologica

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“…CW-TSCPC is performed using the Cyclo G6® Laser System and the G-Probe® Delivery Device (IRIDEX Corp., Mountain View, CA). CW-TSCPC is an established cycloablative treatment that achieves IOP reduction through the destruction of the ciliary body to suppress aqueous humor production [ 22 – 26 ] using 810 nm laser energy [ 27 , 28 ]. The footplate of the G-Probe is held parallel to the visual axis with the shorter edge of the footplate firmly between the anterior border and the middle of the limbus which places the laser fiberoptic over the pars plicata.…”

Section: Introductionmentioning

confidence: 99%

MicroPulse Transscleral Laser Therapy Demonstrates Similar Efficacy with a Superior and More Favorable Safety Profile Compared to Continuous-Wave Transscleral Cyclophotocoagulation

Enrico

Töteberg‐Harms

2022

Journal of Ophthalmology

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Purpose. The aim of this study was to compare effectiveness and safety of MicroPulse transscleral laser therapy (MP-TLT) using the original MicroPulse P3® device and continuous-wave transscleral cyclophotocoagulation (CW-TSCPC) using the G-Probe® device in glaucoma. Methods. Spherical equivalent, intraocular pressure (IOP), best-corrected visual acuity (BCVA), and number of topical or oral ophthalmic pressure-reducing medications were registered at every time point, up to the last follow-up at 12 months. A complete slit-lamp examination was conducted to record the following complications: corneal edema, persistent ocular hypotony (IOP ≤5 mmHg) on two consecutive follow-up visits, choroidal detachment, phthisis bulbi, sympathetic ophthalmia, cystoid macular edema, or other abnormal ocular findings. Success was defined as IOP between 6 and 21 mmHg and >20% reduction in IOP with or without antiglaucoma medications. Results. 47 eyes underwent MP-TLT and 150 CW-TSCPC. At 12 months, success was achieved in 88.6% in the CW-TSCPC group and 87.5% in the MP-TLT group ( p = 0.883). In the CW-TSCPC group, eyes achieved a 42.4% IOP reduction (from 28.3 ± 12.3 mmHg to 15.3 ± 6.0 mmHg) and a 31.1% reduction (from 22.0 ± 7.2 mmHg to 15.7 ± 4.8 mmHg) in the MP-TLT group. Visual acuity remained primarily unaltered in both groups. Conclusion. MP-TLT was as effective in lowering IOP as CW-TSCPC and achieved comparable success. Additionally, MP-TLT demonstrated consistent and effective outcomes at every time point. The improved safety profile of MP-TLT allows the therapeutic spectrum to be broadened, granting ophthalmologists’ treatment of glaucoma in earlier stages of glaucoma than those typically treated with CW-TSCPC, i.e., early to moderate and to patients with good central-vision.

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Scanning Micro-stylus System for Measurement of Micro-aspherics

2010

Springer Series in Advanced Manufacturing

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Cyclodestructive Procedures

Cited by 7 publications

References 22 publications

Efficacy and safety of transscleral cyclophotocoagulation versus cyclocryotherapy in the treatment of intractable glaucoma: A systematic review and meta‐analysis

Efficacy and safety of transscleral cyclophotocoagulation versus cyclocryotherapy in the treatment of intractable glaucoma: A systematic review and meta‐analysis

MicroPulse Transscleral Laser Therapy Demonstrates Similar Efficacy with a Superior and More Favorable Safety Profile Compared to Continuous-Wave Transscleral Cyclophotocoagulation

Scanning Micro-stylus System for Measurement of Micro-aspherics

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