Cycloid Psychoses and Their Differentiation from Affective and Schizophrenic Psychoses

Beckmann, H.; Franzek, Ernst

doi:10.1007/978-3-642-59519-6_112

Cited by 25 publications

(7 citation statements)

References 36 publications

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“…Apart from changes in auditory P300 amplitude, brain scan and cerebral blood flow associated with cycloid psychosis (Beckmann 2001), neither structural nor functional brain alterations have been observed in ATPDs. Yet there seems to be greater evidence of psychosocial factors, especially in low- and middle-income countries and migrant populations.…”

Section: Discussionmentioning

confidence: 99%

“…Cutting (1990) claimed that cycloid psychosis conforms more to an atypical variant of affective disorder. Twin and family studies have found that cycloid psychosis has only a modest hereditary basis; there seems to be greater evidence that it arises when complications during pregnancy and at birth affect the early stages of brain development (Beckmann 2001).…”

Section: Cycloid Psychosismentioning

confidence: 99%

“…Cycloid psychosis is prevalent in women and accounts for many cases of post-partum psychosis; antipsychotic medication must be used cautiously owing to elevated risk of neuroleptic syndrome and catatonia (Beckmann 2001). Follow-up studies have shown that cycloid psychosis fares better than schizophrenia in both course and outcome (Leonhard 1957; Jabs 2004).…”

Section: Early Viewsmentioning

confidence: 99%

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Acute and transient psychoses: clinical and nosological issues

Castagnini¹,

Galeazzi²

2016

BJPsych advances

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SummaryThis article examines the clinical, epidemiological and nosological aspects of short-lived psychotic disorders as currently classified under ‘acute and transient psychotic disorders' in ICD-10 and ‘brief psychotic disorder’ in DSM-5. After describing earlier diagnostic concepts such as bouffée délirante, cycloid psychosis, reactive psychosis and schizophreniform psychosis, we present an overview of the literature and discuss implications for classification, diagnosis and treatment of these conditions, pointing out differences from longer-lasting psychotic disorders.

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Section: Discussionmentioning

confidence: 99%

Section: Cycloid Psychosismentioning

confidence: 99%

Section: Early Viewsmentioning

confidence: 99%

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Acute and transient psychoses: clinical and nosological issues

Castagnini¹,

Galeazzi²

2016

BJPsych advances

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“…Recognition of this psychopathological dimension is of great interest, as the association with schizophrenia is very low (16) and treatment with antipsychotics may either mimic symptoms of catatonia or lead to a neuroleptic malignant syndrome (46,47). Furthermore, the association of catatonic symptoms with the motility subtype of cycloid psychosis requires a specific treatment with mood stabilizers (48–50) and/or low dosis of atypical antipsychotics (51–53), whereas the periodic catatonia of Gjessing can be treated with levothyroxine (5,54). Rapid and sustained improvement of catatonic symptoms has been reported repeatedly with the benzodiazepine lorazepam in a dose of 2–8 mg daily (55,56) and risperidone (52,57).…”

Section: Discussionmentioning

confidence: 99%

Catatonia: the rise and fall of an intriguing psychopathological dimension

Heijden

Tuinier

Pepplinkhuizen

et al. 2002

Acta Neuropsychiatr.

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“…In general, full recovery is reached without residual negative symptoms or cognitive decline. 21 – 23 CP, as such, are not included in the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition (DSM-IV), although pananxiety, perplexity, and motility disorders have been demonstrated in a substantial percentage of patients. 24 – 30 An overview of the characteristics of schizophrenia and CP is presented in Table 1 .…”

Section: Introductionmentioning

confidence: 99%

Cycloid psychoses in the psychosis spectrum: evidence for biochemical differences with schizophrenia

Kerkhof

Fekkes

Heijden

et al. 2016

NDT

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Cycloid psychoses (CP) differ from schizophrenia regarding symptom profile, course, and prognosis and over many decades they were thought to be a separate entity within the psychosis spectrum. As to schizophrenia, research into the pathophysiology has focused on dopamine, brain-derived neurotrophic factor, and glutamate signaling in which, concerning the latter, the N-methyl-d-aspartate receptor plays a crucial role. The present study aims to determine whether CP can biochemically be delineated from schizophrenia. Eighty patients referred for psychotic disorders were assessed with the Comprehensive Assessment of Symptoms and History, and (both at inclusion and after 6 weeks of antipsychotic treatment) with the Positive and Negative Syndrome Scale and Clinical Global Impression. From 58 completers, 33 patients were diagnosed with schizophrenia and ten with CP according to the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition, and Leonhard criteria, respectively. Fifteen patients were diagnosed with other disorders within the psychosis spectrum. At both time points, blood levels of the dopamine metabolite homovanillic acid, brain-derived neurotrophic factor, and amino acids related to glutamate neurotransmission were measured and compared with a matched control sample. Patients with CP showed a significantly better response to antipsychotic treatment as compared to patients with schizophrenia. In CP, glycine levels were elevated and tryptophan levels were lowered as compared to schizophrenia. Glutamate levels were increased in both patient groups as compared to controls. These results, showing marked differences in both treatment outcome and glutamate-related variable parameters, may point at better neuroplasticity in CP, necessitating demarcation of this subgroup within the psychosis spectrum.

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Cycloid Psychoses and Their Differentiation from Affective and Schizophrenic Psychoses

Cited by 25 publications

References 36 publications

Acute and transient psychoses: clinical and nosological issues

Acute and transient psychoses: clinical and nosological issues

Catatonia: the rise and fall of an intriguing psychopathological dimension

Cycloid psychoses in the psychosis spectrum: evidence for biochemical differences with schizophrenia

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