We continue to explore cyclotomic factors in the descent set polynomial Q n (t), which was introduced by Chebikin, Ehrenborg, Pylyavskyy and Readdy. We obtain large classes of factors of the form Φ 2s or Φ 4s where s is an odd integer, with many of these being of the form Φ 2p where p is a prime. We also show that if Φ 2 is a factor of Q 2n (t) then it is a double factor. Finally, we give conditions for an odd prime power q = p r for which Φ 2p is a double factor of Q 2q (t) and of Q q+1 (t).