Cystic fibrosis—Children and adults Tai Chi study (CF CATS2): Can Tai Chi improve symptoms and quality of life for people with cystic fibrosis? Second phase study protocol

Abstract

We believe this is the first trial of Tai Chi for CF. Tai Chi may help with the physiological symptoms of CF and increase levels of exercise by providing a self-management technique and low stress activity. This study will provide data on the feasibility of a randomized controlled trial of Tai Chi for CF, including data for a sample size calculation and will inform future study design.

Physical Activity Counseling for Children With Cystic Fibrosis

“…10 Researchers are also investigating the impact of unconventional forms of physical activity on the health in people with CF, such as the Chinese martial art form tai chi. 11 In all cases, engagement in physical activity was associated with either improvements in health status or no change. In no cases were physical activity and exercise associated with adverse outcomes.…”

Physical exercise training for cystic fibrosis

“…One study was conducted in hospital followed by a 8-to 12-week home-based exercise training programme (Mandrusiak 2011). One study investigated the e ects of active video games during a six-week domiciliary pulmonary rehabilitation programme (NCT02552043) and another study investigated the feasibility and e ectiveness of Tai Chi as exercise intervention (Lorenc 2015). Two studies did not report on the type of exercises included in their training study (Almajan 2011; Oliveira 2010).…”

Children and Adults Tai Chi Study (CF-CATS2): a randomised controlled feasibility study comparing internet-delivered with face-to-face Tai Chi lessons in cystic fibrosis

“…The power calculation had been based upon a finding of a significant improvement in the CFQ-R respiratory domain in our original pilot study of only 10 patients [12]. This study did not quite meet the sample size of 60 published in our original study protocol [21], a not uncommon experience in research [22, 23]; this was partly due to the limited availability of teachers who could travel to participants’ homes, slow recruitment from the clinics and time constraints over the duration of the study. There was also some fall-out of participants from the time of consent to the start of Tai Chi lessons; there was a very low drop-out rate once lessons had started, suggesting that participants engaged well with the Tai Chi intervention in both groups.…”

“…The study received ethical approval from the London – Harrow Research Ethics Committee (14/LO/0327), was registered on the clinicaltrials.gov website (registration number NCT02054377) and the study protocol was published [21]. The study was funded by research grants from two charitable bodies (the Tracie Lawlor Trust for Cystic Fibrosis (the major grant funder) and the Cystic Fibrosis Trust); neither contributed to trial design nor this manuscript.…”