Cystic medullary thyroid cancer

Liberatore, E; Emmolo, I

doi:10.1016/s0039-6060(96)80104-8

Cited by 6 publications

(3 citation statements)

References 2 publications

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“…In the past, complex nodules were often regarded as a benign finding that could be managed conservatively, but it is now widely recognized that these lesions have approximately the same potential for being malignant as does a solid tumour (11-14, 18, 19); moreover, it is also well documented that complex thyroid cancers are commonly papillary tumours, even if follicular, Hurthle cells and medullary histotypes are reported (20)(21)(22).…”

Section: Discussionmentioning

confidence: 99%

Fine needle cytology of complex thyroid nodules

Cappelli¹,

Pirola²,

Castellano³

et al. 2007

eur j endocrinol

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Objective: To evaluate whether a preliminary aspiration (ASP) of the cystic component and/or using spinal needles in complex thyroid nodules (CTN) could improve the adequacy of cytological sampling. Methods: Between January 2004 and December 2006, 386 consecutive patients with CTN were enrolled in this prospective investigation. Ultrasound (US) fine needle aspiration cytology (FNAC) of the solid component of the nodule (one nodule per patient) was performed using two different 25 gauge needles, with (Yale Spinal, YS) or without (Neolus, NS) a stylet, in alternate sequence on consecutive patients. In addition, a subgroup of patients presenting larger cystic component (w50%) was submitted to total aspiration of the cystic component (ASPC) or not submitted (ASPK) before US-FNAC, in alternate sequence within each needle type group. All the samplings were performed by a single endocrinologist. Results: Adequate specimens were observed in 163 (84.5%) and 183 (94.8%) nodules investigated by NS and YS respectively. Sampling with the stylet needle was associated with an overall significant reduction of non-diagnostic specimens (15.5% vs 5.2% by NS and YS respectively, P!0.001). The favourable result obtained with YS was independent from preliminary aspiration of the cystic component (ASPC: 14.8% vs 5.7% by NS and YS; ASPK: 16.2% vs 4.8%, not significant). A logistic regression analysis, taking into account nodule size and presence of intranodal vascularity at ecocolour evaluation of the solid component, confirmed that needle type was the only significant predictor of successful sampling (odds ratio 3.6 (95% confidence interval 1.7-7.6), P!0.001). Conclusions: Our data show that adopting stylet needles to perform FNAC in CTN may significantly improve the percentage of adequate sampling. On the other hand, preliminary aspiration of CTN with large cystic component does not add any advantage.

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Section: Discussionmentioning

confidence: 99%

Fine needle cytology of complex thyroid nodules

Cappelli¹,

Pirola²,

Castellano³

et al. 2007

eur j endocrinol

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“…We have described a case of MTC with a very rare cystic presentation within a multinodular goiter. A few cases of cystic MTC have been reported (5)(6)(7)(8)(9)(10)(11). The main details of these articles are illustrated in Table II.…”

Section: Discussionmentioning

confidence: 99%

Serum Markers Measured in FNA Fluids of Medullary Thyroid Carcinoma Occurring as a Cyst

et al. 2016

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“…(8) Predominantly cystic MTC is rarely encountered, and thus, only a small number have been described. (9)(10)(11)(12)(13) Herein, we report a case of MTC, which presented as a large cystic lesion.…”

Section: Introductionmentioning

confidence: 99%

Cystic Medullary Thyroid Carcinoma: A Case of Undergoing Endoscopic Thyroid Lobectomy

Chung

Seok

Chung

et al. 2015

Korean J Endocr Surg

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On ultrasonography, medullary thyroid carcinoma (MTC) shows hypoechogenicity, an irregular margin, a predominantly solid composition, and microcalcifications, similar to those observed in papillary thyroid carcinoma (PTC). MTC presenting as a cystic lesion is rare, and endoscopic thyroidectomy can be performed for benign thyroid masses and early stage PTC, however it is inappropriate for MTC regardless of cystic change. The authors report a case of cystic MTC found after endoscopic thyroid lobectomy and provide a review of the literature on this topic.

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Cystic medullary thyroid cancer

Cited by 6 publications

References 2 publications

Fine needle cytology of complex thyroid nodules

Fine needle cytology of complex thyroid nodules

Serum Markers Measured in FNA Fluids of Medullary Thyroid Carcinoma Occurring as a Cyst

Cystic Medullary Thyroid Carcinoma: A Case of Undergoing Endoscopic Thyroid Lobectomy

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