Cytohistological correlation in diagnosis of lung tumors by using fiberoptic bronchoscopy: Study of 200 cases

Bodh, Anita; Kaushal, Vijay; Kashyap, Surender; Gulati, Anchna

doi:10.4103/0377-4929.118661

Cited by 25 publications

(27 citation statements)

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“…10 From the above we conclude that squamous cell carcinoma is the most common histological type of lung cancer as is seen in our study also. Small cell carcinoma is the second commonest type of lung cancer in our study which is comparable with the studies done by and Sheema et al and Bodh et al 10,25 Our study is at variance to western literature where incidence of adenocarcinoma has surpassed squamous cell carcinoma. 26,27 In the present study BAL was positive in 301 cases.…”

Section: 22supporting

confidence: 81%

“…7 Bronchial washing (BW), bronchoalveolar lavage (BAL) and brushing specimens can also be obtained for cytopathological examination. [8][9][10][11] Historically, 4 specimens have been shown to be adequate for optimal diagnostic yield in central lesions. 12 The diagnostic sensitivity of bronchial biopsy in diagnosing lung malignancies ranges from 65-83%.…”

Section: Introductionmentioning

confidence: 99%

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Correlation of bronchial biopsy with bronchoalveolar lavage in lung malignancies

Bhat¹,

Nazeir²,

Bashir³

et al. 2016

Int J Res Med Sci

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INTRODUCTIONLung cancer is currently the most frequently diagnosed major cancer in the world and the most common cause of cancer mortality worldwide.1 It comprises about 17% of the total new cancer cases in males and 23% of the total cancer deaths. 2 The incidence is increasing dramatically in women and lung cancer has surpassed breast cancer as a leading cause of cancer death in women. Cancer of the lung most often occurs between age 40 and 70 years with a peak incidence in the fifties and sixties. Only two percent of all cases appear before the age of 40.2 The global incidence of lung cancer is increasing at the rate of 0.5 % per year and is the leading cause of death in most countries. Smoking is considered to be the cause of 85 % of deaths due to lung cancer. 3,4 To combat the disease successfully, lung cancer should be diagnosed at earliest possible stage preferably before the lesion has reached the stage of a visible and palpable ABSTRACT Background: Lung cancer is currently the most frequently diagnosed major cancer in the world and the most common cause of cancer mortality worldwide. It comprises about 17% of the total new cancer cases in males and 23% of the total cancer deaths. The objectives of this study were to compare bronchial biopsy and bronchoalveolar lavage (BAL) cytology and in the diagnosis of carcinoma lung. Study design was comparative study. Methods: The study was done in the Department of Pathology, Sher-i-Kashmir Institute of Medical Science (SKIMS), Srinagar, Kashmir. All patients clinically/radiologically suspected of lung malignancies who presented between April 2004 and May 2012 and underwent both bronchial biopsy and BAL were included in the study. Results: Out of a total of 902 clinically suspected cases of lung cancer tumor was found in 760 cases (84.25%) by biopsy and in 301 cases (33.37%) by BAL. The total number of false positive cases was 31 and false negative cases were 490.Sensitivity of BAL was found to be 35.5% and specificity 78.16%. Conclusions: In the present study yield of diagnosis was highest with the bronchoscopic biopsies and in maximum number of cases, specific histologic diagnosis was made by biopsies only. Though BAL was inferior to bronchial biopsy in diagnosing lung malignancies but it was effective for peripheral lung malignancies and when the patient was at risk of hemorrhage.

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Section: 22supporting

confidence: 81%

Section: Introductionmentioning

confidence: 99%

Correlation of bronchial biopsy with bronchoalveolar lavage in lung malignancies

Bhat¹,

Nazeir²,

Bashir³

et al. 2016

Int J Res Med Sci

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“…The male: female ratio of present study was 2.7:1. Bodh et al 14 found in their study that male: female ratio is 3.35:1 whereas Sareen et al 3 showed male: female ratio of 8.4:1. Cough and shortness of breath was the most common complaints.…”

Section: Discussionmentioning

confidence: 85%

A cytological comparison of efficacy of bronchioalveolar lavage, transbronchial needle aspiration and image guided fine needle aspiration for diagnosis of pulmonary lesions in a rural tertiary care centre

2020

IJPO

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Introduction:Pulmonary lesions include a wide variety of benign and malignant conditions of lung, pleura, mediastinum and vertebrae. Lung cancer is a frequently diagnosed cancer worldwide. 1 Although clinical data, location and radiological findings can narrow down the diagnostic possibilities, a cytological diagnosis is warranted before initiating the specific treatment for the malignant disease. Aims and Objectives: The present study was undertaken with the aim to compare the sensitivity and specificity of bronchioalveolar lavage (BAL), transbronchial needle aspiration cytology (TBNA) and image-guided fine needle aspiration cytology (FNAC) in the evaluation of patients with pulmonary lesions Materials and Methods: The present study was conducted on 100 patients with pulmonary lesions coming to the department of pulmonary medicine at MMIMSR, Mullana. For diagnostic purposes various procedures like BAL, TBNA and image guided FNAC were performed. Cytological examination was carried out in the department of Pathology. Results: Among 100 cases, TBNA was done in 63 cases, BAL in 52 cases and image guided FNAC was performed in 37 cases. Using these cytological techniques, a diagnosis was obtained in 81% cases. The sensitivity and specificity of each technique was assesed. On cytological evaluation, 12% cases had a non-neoplastic diagnosis, whereas 69% cases, malignancy was diagnosed. However, in 19% cases no diagnosis was offered. The most common diagnosis amongst malignant lesions was non-small cell carcinomas. (Squamous cell carcinoma-28%, Adenocarcinoma-23%) followed by small cell carcinoma (8%). Conclusion: Image-guided FNAC of pulmonary lesions is a simple, safe, economically viable technique with low morbidity and offers quick and early diagnosis. Our study revealed that TBNA and FNAC were comparatively better in the diagnosis when compared to BAL.

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“…Brushing yielded highest diagnostic yield (16.4%) compared to aspiration (14.0%) and BAL (11.6%), although the differences between the various techniques were not statistically significant (p=0.08). Bodh et al [14] and Stringfield et al [15] recommended the use of bronchial washings and brushings in addition to biopsy to increase the diagnostic yield. In our study, we found the diagnostic yield in the endobronchially non-visible group to be highest for bronchial brushings (40.65%) followed by bronchial washings (28.57%) and lastly by endobronchial biopsy (18.6%).…”

Section: Discussionmentioning

confidence: 99%

Diagnostic Yield of Various Bronchoscopic Techniques for Evaluation of Lung Cancer: A Retrospective Analysis Comparing Endobronchially Visible and Non–visible Lesions

C¹,

Arora²,

Vadala³

2016

jemds

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Cytohistological correlation in diagnosis of lung tumors by using fiberoptic bronchoscopy: Study of 200 cases

Abstract: Bronchial brushing and washing cytology in combination with imprint cytology aids in the diagnosis of lung tumors. Therefore, all these techniques may be used concurrently along with bronchial biopsy to diagnose lung tumors.

Cited by 25 publications

References 0 publications

Correlation of bronchial biopsy with bronchoalveolar lavage in lung malignancies

Correlation of bronchial biopsy with bronchoalveolar lavage in lung malignancies

A cytological comparison of efficacy of bronchioalveolar lavage, transbronchial needle aspiration and image guided fine needle aspiration for diagnosis of pulmonary lesions in a rural tertiary care centre

Diagnostic Yield of Various Bronchoscopic Techniques for Evaluation of Lung Cancer: A Retrospective Analysis Comparing Endobronchially Visible and Non–visible Lesions

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