Cytohistopathological Study of Salivary Gland Lesions in Bundelkhand Region, Uttar Pradesh, India

Abstract

Background. FNAC is a useful method for evaluating suspicious salivary glands lesions due to its low cost, minimum morbidity, rapid turnaround time, high specificity, and sensitivity. Aim. To know the frequency of the salivary gland lesions and cytohistological correlation in the Jhansi region, Uttar Pradesh, India. Material and Methods. In present study 124 cases were included and cytohistological correlation was made in 86 cases only. FNA was performed by using a 23/24-gauge needle without local anaesthesia. Air dried and 95% ethyl alcohol fixed wet smears were stained with Giemsa stain and Papanicolaou stain, respectively. Paraffin embedded tissue sections were stained with Haematoxylin and Eosin. Results. Parotid gland was the most commonly involved salivary gland. The commonest age group was 20 to 29 years, 30 to 39 years, and 60 to 69 years for nonneoplastic lesions, benign tumours, and malignant tumours, respectively. The overall male to female ratio was 1.17 : 1. The diagnostic accuracy of FNAC was 100%, 93.3%, and 88.2% for nonneoplastic lesions, benign tumours, and malignant tumours, respectively. Conclusion. The high accuracy, sensitivity, and specificity of FNAC confirm that preoperative cytology is a useful, quick, reliable diagnostic technique for rapid diagnosis and suitable for developing countries.

Spectrum of Salivary Gland Lesions in Western Odisha with the Diagnostic Value of F.N.A.C. Correlating with Histomorphology

“…[9] Parotid gland was observed as the most commonly involved site of salivary gland neoplasms-72% of all salivary gland neoplasms. Almost similar distribution of salivary gland neoplasms in the parotid gland has also been described by Omhare et al [7] The present study showed a false positive rate of 4.65%; similar to those of other studies, ranging from 0 to 4.7%. [13,14] The false negative rate in the present study was also 6.97%, which was in concordance with other studies, reporting a range of 2.2% to 24.5%.…”

“…Most common non-neoplastic lesion was chronic sialadenitis followed by suppurative sialadenitis and benign cysts. Most of the nonneoplastic lesions involved the submandibular gland as was observed by Atula et al, [6] and Omhare A et al [7] In the present study, benign neoplasms accounted for 29 cases (29%) similar to Omhare A et al, [7] which was lower than other reports which ranged from 49 to 83%. [8][9] We observed the pleomorphic adenoma as the most common benign neoplasm followed by Warthin's tumour and basal cell adenoma and the predominance of these two benign neoplasms was similar to number of studies.…”

“…It also aids the clinicians in management planning. [3] A total of 100 cases underwent cytology of salivary gland masses which were categorised into non neoplastic and neoplastic (benign and malignant) groups. The most common gland affected in the study was parotid (72%) which is similar to study done by Eveson JW and Cawson RA.…”

“…Specific diagnosis is given on the basis of the classification of the tumours which helps the clinicians in planning the management of the lesion. [3] Meta-analysis and comparative systematic review confirm that FNAC is effective in head and neck masses. [4] This method is applicable to palpable lesions.…”

“…[ Table 7] In our study, sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) of preoperative FNA cytology of salivary gland tumours were 80%, 88.23%, 83.33%, and 85.71%, respectively; however, overall diagnostic accuracy for all salivary gland lesions was 91.78%, indicating good results compared to various other studies. [7,8,15] …”