Cytological picture of the oral mucosa in patients with gastric and colon cancer

Kędra, Bożena; Chomczyk, M; Złotkowski, Marcin; Stokowska, W; Borsuk, A. D.; Bicz, Mieczysław; Pietruska, Małgorzata; Tokajuk, Grażyna; Charkiewicz, Radosław; Czajka, P.; Chyczewski, L; Zimnoch, L; Kędra, Bogusław

doi:10.5603/fhc.2012.0051

Cited by 6 publications

(5 citation statements)

References 4 publications

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“…A discussion of our own results is difficult because there is still not much data on the evaluation of the state of the oral mucosa in patients with gastrointestinal cancer. Fukushima et al have presented patients with advanced gastric cancer who have diffuse changes in the angles of the lips, oral mucosa and esophagus of the type acanthosisnigricans [14].…”

Section: Discussionmentioning

confidence: 99%

Cytological picture of the oral mucosa in patients with gastric and colon cancer

Kędra

Chomczyk²,

Złotkowski³

et al. 2012

Folia Histochem Cytobiol.

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The incidence of malignant gastrointestinal cancers in Poland has been constantly growing, which has led to an intensification of the search for new markers of the early clinical stage of this disease. The oral cavity,as the first part of the gastrointestinal tract, has a very important role. The oral cavity presents symptoms of both typically stomatological and systemic diseases. Oral cancers, benign or malignant, may originate and grow in any of the tissues of the mouth, and within this small area they may be of varied clinical, histological and biological features. These can be lesions typically observed in the oral cavity, but also characteristic of cases where the symptoms occur both in the mouth and in other body parts. The aim of this study was to present a cytological picture of the oral mucosa in patients with gastric and colon cancer and to compare the cytological picture with that obtained from a group of patients with no cancer, using the Papanicolaou classification and the Bethesda system. The study was conducted in 126 patients treated surgically in the II General and Gastroenterological Surgery Clinic between 2006 and 2008. All patients were divided into two groups based on the type of lesions. In both of the studied groups, more than half of the patients did not present any abnormalities in the mucosa of the mouth, lips and cheeks in the physical examination. None of the patients had erosion, ulceration or lesions typical of leukoplakia or lichen planus. No malignant cells were detected in either of the studied groups, and there were no well-defined lesions found in the oral cavity that would distinguish the patients with gastrointestinal cancer.

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Section: Discussionmentioning

confidence: 99%

Cytological picture of the oral mucosa in patients with gastric and colon cancer

Kędra

Chomczyk²,

Złotkowski³

et al. 2012

Folia Histochem Cytobiol.

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“…However, for reporting cervical cytology, TBS is the most commonly used and appropriate criterion. Referring to [38,39], the specific classification criteria and corresponding relations of these four systems are shown in Table 1.…”

Section: History Of Reporting Terminologymentioning

confidence: 99%

A Survey on Deep Learning-based Cervical Cytology Screening: from Cell Identification to Whole Slide Image Analysis

Jiang

Shen

et al. 2023

Preprint

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Cervical cancer is one of the most common cancers in daily life. Early detection and diagnosis can effectively help facilitate subsequent clinical treatment and management. With the growing advancement of artificial intelligence (AI) and deep learning (DL) techniques, an increasing number of computer-aided diagnosis (CAD) methods based on deep learning have been applied in cervical cytology screening. In this paper, we survey more than 70 publications since 2016 to provide a systematic and comprehensive review of DL-based cervical cytology screening. First, we provide a concise summary of the medical and biological knowledge pertaining to cervical cytology, since we hold a firm belief that a comprehensive biomedical understanding can significantly contribute to the development of CAD systems. Then, we collect a wide range of public cervical cytology datasets. Besides, image analysis approaches and applications including cervical cell identification, abnormal cell or area detection, cell region segmentation and cervical whole slide image diagnosis are summarized. Finally, we discuss the present obstacles and promising directions for future researches in automated cervical cytology screening.

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“…The identification of basic inflammatory, dysplasia, or malignant alterations in all smears cells was done according to Papanicolaou classification; Class I: absence of abnormal or atypical cells; Class II: normal cells with inflammatory changes, no evidence of malignancy; Class III: suggestive, but not conclusive for malignancy; Class IV: cytology strongly suggestive of malignancy; Class V: cytology conclusive for malignancy. 16,17 The type of predominant cell (cellularity) in each smear was analysed also. The quantitative analysis of the AgNOR was carried out through light microscopy by binocular Olympus BX41™ (Olympus, Tokyo, Japan), adapted with a WH 10×-H/22 ocular and PLAN 100×/0.25.…”

Section: Methodsmentioning

confidence: 99%

Exfoliative Cytology in the Oral Mucosa of Patients with Fanconi Anaemia: A Morphometric Approach

Machado¹,

D'Agulham²,

Chaiben³

et al. 2017

J Dent Indones

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Patients with Fanconi anaemia (FA) are prone to develop squamous cell carcinomas at an early age. Exfoliative cytology can be used to detect changes to the health of the oral mucosa. Objective: The aim of this study was to evaluate morphometrical and morphological changes using exfoliative cytology and to analyse and quantify the proliferative activity using silver nucleolar organiser regions (AgNOR) in epithelial cells of the tongue in FA patients, after haematopoietic stem cell transplantation (HSCT). Methods: Oral smears were collected from the tongues of 20 FA children and adolescents after haematopoietic stem cell transplantation (FA) and 20 healthy children (C) using exfoliative cytology. The smears were stained using the Papanicolaou technique and silver impregnation. The cells were morphologically analysed and the nuclear area (NA), the cytoplasmic area (CA), and the nucleusto-cytoplasm area ratio (NA/CA) were calculated. Results: Mean values for the FA and C groups were: NA (71.85 and 55.21µm²; p< 0.01); CA (2127.48 and 1441.61µm²; p< 0.01); NA/CA (0.03 and 0.04; p< 0.01), respectively. A significant increase in the NA and CA for the FA group (p< 0.01) was seen, and an alteration in the NA/CA ratio. No morphological differences were found between the groups. Class I smears were predominant in both groups. No differences were found between the groups for the mean values of AgNORs per nucleus. Conclusion: This study suggests that morphological changes occurred in the oral epithelium cells of children and adolescents with Fanconi anaemia when subjected to HSCT.

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Cytological picture of the oral mucosa in patients with gastric and colon cancer

Cited by 6 publications

References 4 publications

Cytological picture of the oral mucosa in patients with gastric and colon cancer

Cytological picture of the oral mucosa in patients with gastric and colon cancer

A Survey on Deep Learning-based Cervical Cytology Screening: from Cell Identification to Whole Slide Image Analysis

Exfoliative Cytology in the Oral Mucosa of Patients with Fanconi Anaemia: A Morphometric Approach

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