Cytologie der Cerebrospinalflüssigkeit

Sayk, J

doi:10.1007/978-3-7091-5096-2_8

Cited by 27 publications

(13 citation statements)

References 15 publications

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“…However, some inves tigators were o f the opinion, that CSF lympho cytes originate partially from the leptomeninges (Fischer, 1906;Szecsi, 1911;Sayk, 1960;Bisclioff, 1964Bisclioff, , 1971 In the last 15 years immunology has devel oped rapidly, in spite o f which only sporadic and partial attempts have been made to bring these new findings into CSF cytology (Guseo, 1972(Guseo, , 1974Oehmichen, 1973;Allen et al, 1975). One must consider that about 15 years ago the role o f lymphocytes was still question able -here was a relatively small cell that morphologically was dull and unattractive, while in contrast, the cells that apparently were involved in an active immunological process were large, full o f organelles, and actively syn thesizing proteins and/or antibodies.…”

mentioning

confidence: 99%

Classification of Cells in the Cerebrospinal Fluid

Guseo¹

1977

Eur Neurol

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Comparative ultrastructural findings of meninges, ventricular ependyma and choroid plexus of mammals including man were summarized with the aim of a better understanding as to which cells can play a role as macrophages in the cerebrospinal fluid (CSF) cytology. Differences between phagocytic capacity of pial cells and arachnoid cells were emphasized. Comparative investigations showed that most of the cells in the CSF originate from the blood. Scanning electron microscopy of the subarachnoid space and cytological investigation of the CSF gave the result that haematogenous cells belong to the normal cell population of the subarachnoid space of normal individuals. These cells in the CSF react as their equivalents in the blood, that is, after confrontation with antigens the monocytes transform into macrophages, sometimes into multinucleated giant cells, the T and B lymphocytes transform into blast cells. On the basis of immunological and ultrastructural results, the classification of CSF cells in normal and pathological conditions has been proposed.

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confidence: 99%

Classification of Cells in the Cerebrospinal Fluid

Guseo¹

1977

Eur Neurol

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“…In recent years, using the Shandon cytocentrif uge has been proved to be a rapid, accurate technique for diagnosing meningeal leukemia or lymphoma (Drewinko et al 1973;Ducos et al 1979). Although centrifugal force would cause morphologic changes in cells, this method would lose less cells than Sayk's spontaneous sedimentation (Sayk, 1962 CSF. In order to reduce the mortality rate and sequelae, the therapy should be started before the organisms are identified.…”

Section: Discussionmentioning

confidence: 99%

Cerebrospinal fluid cytology using a cytocentrifuge in the early diagnosis of cause of meningitis.

et al. 1985

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“…In the acute phase, blast forms -large or 'trans formed' lymphocytes and some plasma cells including 'immature' types -are observed in addition to the neutrophilic reaction. In the convalescent phase, these cells are replaced by small lymphocytes, 'mature' plasma cells and monohistiocytes (17,(21)(22)(23). Dommasch etal.…”

Section: Discussionmentioning

confidence: 99%

Zoster Meningitis and Radiculomeningitis after Tick Bite

Shoji¹,

Dommasch²

1979

Eur Neurol

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Cytological changes in 9 samples of cerebrospinal fluid (CSF) from 5 patients with zoster meningitis and 12 samples from 5 patients with radiculomeningitis after tick bite were examined. 5 days after the onset of the skin eruption, the CSF cells in zoster meningitis consisted of many mononuclear blast forms – large lymphocytes and ‘immature’ plasma cells. 11–15 days after the onset of the skin rash, they were replaced by small lymphocytes, some ‘mature’ plasma cells and monohistiocytes. In radiculomeningitis after tick bite, however, the CSF cells examined 10–21 days after the onset of radicular pain consisted of many large lymphocytes, immature plasma cells and a few neutrophils. From these findings, it might be suggested that the acute meningeal reaction of zoster meningitis subsides within about 1 week after the onset of the skin rash, but that of radiculomeningitis after tick bite continues at least for 2–3 weeks after the onset of radicular pain.

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Cytologie der Cerebrospinalflüssigkeit

Cited by 27 publications

References 15 publications

Classification of Cells in the Cerebrospinal Fluid

Classification of Cells in the Cerebrospinal Fluid

Cerebrospinal fluid cytology using a cytocentrifuge in the early diagnosis of cause of meningitis.

Zoster Meningitis and Radiculomeningitis after Tick Bite

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