Cytomegalovirus in Non-B Post-Transfusion Hepatitis

Fiala, Milan; Rp, Nelson; Myhre, Byron A.; Guze, Lucien B.; Overby, L. R.; Ling, Chung‐Mei

doi:10.1016/s0140-6736(74)90843-5

Cited by 5 publications

(1 citation statement)

References 8 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In addition, hepatitis can be the major presenting symptom of CMV infection in previously healthy adults (Lamb & Stern, 1966;Carter, 1968;Shusterman, Frauenhoffer & Kinsey, 1978) and this may be accompanied by jaundice (Lamb & Stern, 1966;Shusterman, Frauenhoffer & Kinsey, 1978). Cytomegalovirus hepatitis has also been described following blood transfusion (Toghill et al 1967;Fiala et al 1974). Cytomegalovirus has not been found to be associated with chronic liver disease (Toghill, Williams & Stern, 1969 Hepatitis is frequently found in cases of congenital CMV infection.…”

Section: Hepatitismentioning

confidence: 99%

The status of CMV as a human pathogen

Griffiths

Grundy

1988

Epidemiol. Infect.

View full text Add to dashboard Cite

Cytomegalovirus (CMV) is a common infectious agent which is well adapted to its host. Following primary infection, which is almost always asymptomatic in people with normal immunity, the virus establishes latency at sites which are unknown. The virus is probably maintained in this latent state by immune surveillance mechanisms since immunosuppression frequently leads to reactivation of virus.Cytomegalovirus has been identified in most anatomical areas of the human body. The aim of this article is to define criteria for pathogenicity so that clinical and experimental data can be reviewed to determine if CMV is likely to cause disease at these various clinical sites. Thus, patients have been shown to die frequentlywithCMV but do they diefromit?

show abstract