Cytotoxicity and estrogenicity of a novel 3-dimensional printed orthodontic aligner

Pratsinis, Harris; Papageorgiou, Spyridon N.; Panayi, Nearchos; Iliadi, Anna; Eliades, Theodore; Kletsas, Dimitris

doi:10.1016/j.ajodo.2022.06.014

Cited by 34 publications

(28 citation statements)

References 33 publications

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“…Pratsinis et al [ 54 ] evaluated the cytotoxicity and estrogenicity of aligners printed in the Tera Harz TC-85A resin (Graphy Inc.) with the SprintRay Pro 55 3D printer (SprintRay Inc.) and stored for 14 days in water at 37 °C. The eluates released by the resin did not adversely influence the viability of human gingival fibroblasts that had been exposed to them for 14 days.…”

Section: Resultsmentioning

confidence: 99%

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Clinically Relevant Properties of 3D Printable Materials for Intraoral Use in Orthodontics: A Critical Review of the Literature

et al. 2023

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The review aimed at analyzing the evidence available on 3D printable materials and techniques used for the fabrication of orthodontic appliances, focusing on materials properties that are clinically relevant. MEDLINE/PubMed, Scopus, and Cochrane Library databases were searched. Starting from an initial retrieval of 669 citations, 47 articles were finally included in the qualitative review. Several articles presented proof-of-concept clinical cases describing the digital workflow to manufacture a variety of appliances. Clinical studies other than these case reports are not available. The fabrication of aligners is the most investigated application of 3D printing in orthodontics, and, among materials, Dental LT Clear Resin (Formlabs) has been tested in several studies, although Tera Harz TC-85 (Graphy) is currently the only material specifically marketed for direct printing of aligners. Tests of the mechanical properties of aligners materials lacked homogeneity in the protocols, while biocompatibility tests failed to assess the influence of intraoral conditions on eluents release. The aesthetic properties of 3D-printed appliances are largely unexplored. The evidence on 3D-printed metallic appliances is also limited. The scientific evidence on 3D printable orthodontic materials and techniques should be strengthened by defining international standards for laboratory testing and by starting the necessary clinical trials.

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Section: Resultsmentioning

confidence: 99%

“…In addition, no xenoestrogenic activity was observed. Based on these findings, the authors concluded that the tested resin is biocompatible [ 54 ].…”

Section: Resultsmentioning

confidence: 99%

Clinically Relevant Properties of 3D Printable Materials for Intraoral Use in Orthodontics: A Critical Review of the Literature

et al. 2023

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“…Duran exhibited the lowest levels of toxicity. Table 2 shows that all the materials tested in the study exhibited low in vitro toxicity on the tested cells [ 104 , [106] , [107] , [108] ].…”

Section: Properties Of Clear Aligner Materialsmentioning

confidence: 99%

Advances in orthodontic clear aligner materials

Bichu

Alwafi

Liu

et al. 2023

Bioactive Materials

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“…The literature has documented the use of DLP printers such as SprintRay Pro (Sprintray, Los Angeles, Calif., USA) (6,23,27), MiiCraft 125 (Young Optics Inc., Hsinchu City, Taiwan) (6,22), Uniz 4K (Uniz, San Diego, Calif., USA) (28), and Moonray S100 (Sprintray, Los Angeles, Calif., USA) (29); LCD printers (6)…”

Section: D Printersmentioning

confidence: 99%

“…The post-preparation of the printed aligner material encompasses procedures like cleaning the uncured residual resin, support removal, and post-production curing. For the Tera Harz TC-85 aligners, recommendations mention the process of cleaning by centrifugation for around 3-4 min (6,27) or removal with a soft scraper (28). This is followed by support removal and post-production curing with Cure M (Graphy, Seoul, Korea).…”

Section: Post-processingmentioning

confidence: 99%

Integrated manufacturing of direct 3D-printed clear aligners

Rajasekaran

Chaudhari

2023

Front. Dent. Med

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The inception of the laboratory work for a removable tooth moving appliance construction by sectioning the teeth from the malocclusion model to align them with wax and achieve minor dental correction has evolved into a state of digital planning and appliance manufacturing for a wide spectrum of malocclusion. The disruptive technology of directly printing clear aligners has drawn the clinician and researcher's interest in the orthodontic fraternity contemporarily. This workflow enables to the development of an in-house aligner system with complete control over desired aligner thickness, extent, and attachments; also technically resource-efficient with greater accuracy by excluding all the intermediate steps involved in the thermoforming method of manufacturing. This promising exploratory subject demands to be well-received with further research-based improvements. This article intends to summarize the digital orthodontic workflow and the literature evidence.

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Cytotoxicity and estrogenicity of a novel 3-dimensional printed orthodontic aligner

Cited by 34 publications

References 33 publications

Clinically Relevant Properties of 3D Printable Materials for Intraoral Use in Orthodontics: A Critical Review of the Literature

Clinically Relevant Properties of 3D Printable Materials for Intraoral Use in Orthodontics: A Critical Review of the Literature

Advances in orthodontic clear aligner materials

Integrated manufacturing of direct 3D-printed clear aligners

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